Membrane News and Research

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New model explains controversies over saturated fats and heart disease risk

In science, sometimes a new perspective can turn our interpretation of the data upside-down, and necessitate a paradigm shift.

22 Jan 2021

How have new SARS-CoV-2 strains become more transmissible?

A new study discusses the effect of specific mutations on the sensitivity of SARS-CoV-2's spike protein to elastase, and on the intramolecular conformational changes.

22 Jan 2021

SARS-CoV-2’s nonstructural proteins dysregulate immune responses, study finds

Researchers provide an overview of SARS-CoV-2 and its life cycle pathways, addressing the functional changes in the viral proteins, providing important strategic clues to help that may help in the ongoing development of therapies against COVID-19.

22 Jan 2021

ACE2 and furin levels linked to inflammation in smokers with COVID-19

A new study reports the level of ACE2 and furin, two enzymes that are intimately linked to infection with SARS-CoV-2, the causative agent of COVID-19.

21 Jan 2021

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Researchers develop a novel, simple and affordable method for N-glycan fingerprinting based on enzymatic fluorescent glycan labeling and electrophoresis. This new method may help us understand important changes in glycosylation in the SARS-CoV-2 spike protein – something which could inform future therapeutic research.

20 Jan 2021

Cannabidiol kills bacteria responsible for gonorrhea, meningitis, and legionnaires disease

Synthetic cannabidiol, better known as CBD, has been shown for the first time to kill the bacteria responsible for gonorrhea, meningitis and legionnaires disease.

20 Jan 2021

Study: Oligodendrocytes play key role in the distribution of energy-rich molecules

The human brain has about as many neurons as glial cells. These are divided into four major groups: the microglia, the astrocytes, the NG2 glial cells, and the oligodendrocytes.

19 Jan 2021

Carbon-based nanomaterials as potential COVID-19 treatments

An international team of researchers says that carbon-based nanomaterials (CBNs) could represent promising new approaches to treating coronavirus disease 2019 (COVID-19) pneumonia that is complicated by a secondary bacterial, viral or fungal infection.

19 Jan 2021

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Magnetic nanoparticles raise hopes of treatments for Parkinson’s.

19 Jan 2021

Are antibiotic regimens for critical COVID-19 patients with bacterial superinfection unnecessarily high?

A new study by researchers at Northwestern University Feinberg School of Medicine, USA, shows that antibiotic regimens for critically ill COVID-19 patients with bacterial superinfections may be promoting an unnecessarily high.

19 Jan 2021

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

Recently researchers from the United States reported the results of a SARS‐CoV‐2 genomic surveillance conducted between April 2020 and January 2021 in Columbus, Ohio. Their work is released as a preprint on the bioRxiv server.

18 Jan 2021

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Researchers investigated how cancer genes lead to the breakdown of the capsule that prevents cancerous cells from invading the surrounding healthy tissues and - find a hijacked "molecular crowbar".

18 Jan 2021

Researchers figure out the precise mechanics involved in cell motility

Theoretical physicists from Berlin teamed up with experimental physicists from Munich to determine the precise mechanics involved in cell motility. The findings were published in the journal Proceedings of the National Academy of Sciences.

18 Jan 2021

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

The potentially deadly COVID-19 has not affected animals with corresponding severity. To understand the mechanism of severe disease, animal models have been used. This includes a mouse model that expresses human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter (K18-hACE2). A new study indicates that this may not be a faithful model of human lethal infection with SARS-CoV-2.

18 Jan 2021

New SARS-CoV-2 variant emerges in the U.S.

Even as the rollout of vaccines all over the world brings a glimmer of hope that the current coronavirus disease 2019 (COVID-19) pandemic may end in the near future, new variants continue to emerge, some with the potential to escape vaccine-induced or therapeutic antibodies. Now, a new preprint research paper published on the bioRxiv server describes a new American variant that may have become the dominant strain in the USA.

18 Jan 2021

Combination therapy reduces recovery time in COVID-19 patients, clinical trial finds

A clinical trial involving COVID-19 patients hospitalized at UT Health San Antonio and University Health, among roughly 100 sites globally, found that a combination of the drugs baricitinib and remdesivir reduced time to recovery, according to results published Dec. 11 in the New England Journal of Medicine.

16 Jan 2021

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

Mitochondria are vital for the human body as cellular powerhouses: They possess more than 1,000 different proteins, required for many central metabolic pathways.

16 Jan 2021

New antiviral repurposing study finds peptides that could prevent SARS-CoV-2-ACE2 binding

A new study reports the antiviral potential of peptides against SARS-CoV-2's spike protein.

15 Jan 2021

Study reports promising new monoclonal antibody against SARS-CoV-2’s spike protein

An encouraging new study describes a promising new therapeutic antibody that shows potent neutralizing activity against SARS-CoV-2, the causative agent of COVID-19.

15 Jan 2021

Study may lead to novel synthetic drugs to combat bacterial infections

Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of novel synthetic drugs to combat bacterial infections.

15 Jan 2021

Membrane News and Research

New model explains controversies over saturated fats and heart disease risk

How have new SARS-CoV-2 strains become more transmissible?

SARS-CoV-2’s nonstructural proteins dysregulate immune responses, study finds

ACE2 and furin levels linked to inflammation in smokers with COVID-19

Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation

Cannabidiol kills bacteria responsible for gonorrhea, meningitis, and legionnaires disease

Study: Oligodendrocytes play key role in the distribution of energy-rich molecules

Carbon-based nanomaterials as potential COVID-19 treatments

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Are antibiotic regimens for critical COVID-19 patients with bacterial superinfection unnecessarily high?

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Researchers figure out the precise mechanics involved in cell motility

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

New SARS-CoV-2 variant emerges in the U.S.

Combination therapy reduces recovery time in COVID-19 patients, clinical trial finds

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

New antiviral repurposing study finds peptides that could prevent SARS-CoV-2-ACE2 binding

Study reports promising new monoclonal antibody against SARS-CoV-2’s spike protein

Study may lead to novel synthetic drugs to combat bacterial infections

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