Protein C News and Research

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Study to understand how protein motor works for development of targeted cancer therapies

Researchers at Warwick Medical School have shown for the first time how a protein motor, Kif15, uses acrobatic flexibility to navigate within the mitotic spindle. Understanding how it works could prove vital for the development of targeted cancer therapies.

27 Mar 2014

Research points strong reason to develop new class of antidepressant drug

Scientists have shown for the first time that a chemical in the brain called galanin is involved in the risk of developing depression.

From The University of Manchester 27 Mar 2014

Study: Genetics could explain why environmental exposures can trigger onset of rheumatoid arthritis

A new international study has revealed how genetics could explain why different environmental exposures can trigger the onset of different forms of rheumatoid arthritis.

From The University of Manchester 27 Mar 2014

Study points to potential culprit that kills motor neurons in ALS

Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is marked by a cascade of cellular and inflammatory events that weakens and kills vital motor neurons in the brain and spinal cord. The process is complex, involving cells that ordinarily protect the neurons from harm. Now, a new study by scientists in The Research Institute at Nationwide Children's Hospital points to a potential culprit in this good-cell-gone-bad scenario, a key step toward the ultimate goal of developing a treatment.

27 Mar 2014

Study: Dab2 can exhibit neuroprotective effects in Alzheimer's by regulating TGF-β1/SMAD signaling

Transforming growth factor-beta (TGF-β) type II receptor (TβRII) levels are extremely low in the brain tissue of patients with Alzheimer's disease.

27 Mar 2014

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Infectious disease specialists at the Johns Hopkins Children's Center have identified a protein that regulates the body's immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune systems.

27 Mar 2014

New international partnership aims to increase wheat yields by 50% by 2034

A new international partnership aims to increase wheat yields by 50 percent by 2034. This will address demand for wheat - one of the world's most important crops - that is growing much faster than production.

26 Mar 2014

Low dose injections of artificial properdin provides protection against septic diseases in mice

Breakthrough MRC-funded study from University of Leicester shows low dose injections of artificial properdin provides substantial protection against septic diseases in mice

26 Mar 2014

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Adaptimmune today announced that it has been awarded a grant of £2.1 million from the Biomedical Catalyst Fund, managed by the UK’s innovation agency the Technology Strategy Board and the Medical Research Council. The prestigious award will expedite the development of Adaptimmune’s second engineered T cell therapy programme into the clinic in triple negative breast cancer.

26 Mar 2014

HIV and Hepatitis C vaccines now closer to reality

Plans for a new type of DNA vaccine to protect against the deadly HIV and Hepatitis C viruses have taken an important step forward, with University of Adelaide researchers applying for a patent based on groundbreaking new research.

26 Mar 2014

SLU researchers awarded NIH grants to search for a drug to cure hepatitis B

Two grants from the National Institutes of Health will allow Saint Louis University researchers to build on breakthroughs in understanding the hepatitis B virus and begin the search for a drug to cure - not just halt - the illness.

26 Mar 2014

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died.

26 Mar 2014

TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

Scientists at Forsyth, along with a colleague from Northwestern University, have discovered that the protein, Transgultaminase 2 (TG2), is a key component in the process of gum disease. TG2 is widely distributed inside and outside of human cells. The scientists found that blocking some associations of TG2 prevents the bacteria Porphyromonas gingivalis (PG) from adhering to cells. This insight may one day help lead to novel therapies to prevent gum disease caused by PG.

26 Mar 2014

MIT biological engineers trying to adapt MRI to visualize gene activity inside the brains of living animals

Doctors commonly use magnetic resonance imaging (MRI) to diagnose tumors, damage from stroke, and many other medical conditions. Neuroscientists also rely on it as a research tool for identifying parts of the brain that carry out different cognitive functions.

26 Mar 2014

Renal Ventures Management publishes first cookbook of kidney friendly recipes for renal patients

In recognition of Kidney Health Awareness Month, Renal Ventures Management, LLC (RVM), a leading provider of dialysis services for patients suffering from chronic kidney failure, has published its first cookbook of kidney friendly recipes for it renal patients and their families.

25 Mar 2014

The Center for Applied Nanotechnology presents a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays

The nano-experts from the Center for Applied Nanotechnology (CAN) GmbH expand their product portfolio by CANdots® Series G - His Detect, which is a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays. It is easy to handle, highly sensitive as well as time saving compared to standard methods available on the market, e.g. ECL.

25 Mar 2014

Researchers receive grants to advance work in prevention of premature birth

Researchers at UT Southwestern Medical Center received grants totaling $600,000 from the March of Dimes Foundation to advance their work in the prevention of premature birth, which affects about one out of nine babies born annually in the U.S. and is the leading cause of newborn death.

25 Mar 2014

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

Mathematicians at the University of York have joined forces with experimentalists at the University of Leeds to take an important step in discovering how viruses make new copies of themselves during an infection.

25 Mar 2014

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Case Western Reserve University researchers have discovered a novel population of neutrophils, which are the body's infection control workhorses. These cells have an enhanced microbial killing ability and are thereby better able to control infection.

25 Mar 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

Protein C News and Research

Study to understand how protein motor works for development of targeted cancer therapies

Research points strong reason to develop new class of antidepressant drug

Study: Genetics could explain why environmental exposures can trigger onset of rheumatoid arthritis

Study points to potential culprit that kills motor neurons in ALS

Study: Dab2 can exhibit neuroprotective effects in Alzheimer's by regulating TGF-β1/SMAD signaling

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

New international partnership aims to increase wheat yields by 50% by 2034

Low dose injections of artificial properdin provides protection against septic diseases in mice

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

HIV and Hepatitis C vaccines now closer to reality

SLU researchers awarded NIH grants to search for a drug to cure hepatitis B

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

MIT biological engineers trying to adapt MRI to visualize gene activity inside the brains of living animals

Renal Ventures Management publishes first cookbook of kidney friendly recipes for renal patients

The Center for Applied Nanotechnology presents a ready-to-use reagent for the detection of poly-histidine tagged proteins in Blot assays

Researchers receive grants to advance work in prevention of premature birth

Researchers develop mathematical model that provides insights about molecular mechanisms behind virus assembly

Researchers discover novel population of neutrophils that exhibit enhanced microbial killing activity

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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