Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

New biofilm discovery may pave way to undermining antibiotic-resistant Pseudomonas

The bacterium known as Pseudomonas aeruginosa is an unwelcome visitor in the human body. Serious infections can result when a bunch of these bugs settle together on a surface to form a biofilm - a community of microbes like the slime on spoiled food, but in this case residing inside a person.

29 Oct 2025

TRF1 protein depletion linked to leaner mice and altered metabolism

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

27 Oct 2025

Pigments extracted from the henna dye could be used to treat liver disease

Lawsonia inermis is best known for making henna, a versatile dye that is used to change the color of skin and clothes. Now, researchers from Osaka Metropolitan University have found another use for the pigments extracted from the dye: treating liver disease.

27 Oct 2025

Study finds bright nights raise risk for stroke and heart failure in adults over 40

A large UK Biobank study found that higher night-time light exposure is linked to significantly greater risks of coronary artery disease, stroke, heart failure, and other cardiovascular conditions. The findings suggest maintaining darker nights and adequate daytime light could support heart health.

26 Oct 2025

PAI-1 may be a promising therapeutic target for preventing age-related muscle and bone loss

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 11, 2025, titled "Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice."

23 Oct 2025

Common chemical tetrachloroethylene may be harmful to the liver

Liver disease is usually caused by one of three factors: alcohol consumption, fat buildup in the liver linked to obesity, diabetes and high cholesterol, or hepatitis B and C.

23 Oct 2025

New gene-editing method can correct many disease-causing mutations in mammalian cells

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a different combination of mutations.

23 Oct 2025

New study solves lung transplant rejection mystery

More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical mystery.

22 Oct 2025

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University of Technology, University of Queensland, and Nanjing Stomatological Hospital has introduced groundbreaking three-dimensional (3D) dynamic cell co-culture models to simulate metabolic dysfunction-associated steatotic liver disease (MASLD) progression stages.

22 Oct 2025

Nanoparticles offer new hope for treating alcohol-related liver disease

Across the world, more than 1.5 billion people suffer from chronic liver disease. The U.S. Centers for Disease Control and Prevention reports that it kills more than 52,000 people a year in the United States alone - the ninth most common cause of death in the nation.

17 Oct 2025

CRATERs identified as key sites for T cell-mediated tumor destruction

Like the surface of the moon, new research published today in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing. These craters could serve as good markers for immunotherapy success.

17 Oct 2025

Blocking key protein restores healthy lung function and reduces fibrosis in mice

Pulmonary fibrosis is a deadly disease in which the lungs become thickened and scarred, gradually losing their ability to deliver oxygen to the body.

16 Oct 2025

Longevity gene offers hope for children with progeria

A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.

15 Oct 2025

Study links gut dysbiosis with severe steatosis in MASLD

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD).

15 Oct 2025

Immune checkpoint inhibitor TIGIT found to promote tissue healing

Immune checkpoint inhibitors are well known as a form of cancer treatment. Researchers at UZH have now identified a new, important function of these inhibitors: promotion of tissue healing.

15 Oct 2025

Targeting SIRT7 offers new strategy against liver fibrosis

Liver fibrosis, a progressive scarring of the liver tissue, represents a major global health burden with limited treatment options.

10 Oct 2025

Blood biomarkers offer hope for early detection of interstitial lung disease

UVA Health lung researchers are developing a promising approach to detecting patients at risk of interstitial lung disease (ILD), an increasingly common condition that is a leading reason for lung transplants.

10 Oct 2025

Air pollution plays a significant role in the development of metabolic disorders

Long-term exposure to fine air pollution can impair metabolic health by disrupting the normal function of brown fat in mice. A study co-led by the University of Zurich shows that this occurs through complex changes in gene regulation driven by epigenetic mechanisms.

9 Oct 2025

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic concern; they often cause distressing symptoms such as chronic pain, itching, and restricted movement.

9 Oct 2025

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one third of the adult population. This disorder is characterized by the accumulation of fat in liver cells, which has severe liver consequences and is also associated with a high mortality rate from cardiovascular disease.

6 Oct 2025

Fibrosis News and Research

Further Reading

New biofilm discovery may pave way to undermining antibiotic-resistant Pseudomonas

TRF1 protein depletion linked to leaner mice and altered metabolism

Pigments extracted from the henna dye could be used to treat liver disease

Study finds bright nights raise risk for stroke and heart failure in adults over 40

PAI-1 may be a promising therapeutic target for preventing age-related muscle and bone loss

Common chemical tetrachloroethylene may be harmful to the liver

New gene-editing method can correct many disease-causing mutations in mammalian cells

New study solves lung transplant rejection mystery

Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression

Nanoparticles offer new hope for treating alcohol-related liver disease

CRATERs identified as key sites for T cell-mediated tumor destruction

Blocking key protein restores healthy lung function and reduces fibrosis in mice

Longevity gene offers hope for children with progeria

Study links gut dysbiosis with severe steatosis in MASLD

Immune checkpoint inhibitor TIGIT found to promote tissue healing

Targeting SIRT7 offers new strategy against liver fibrosis

Blood biomarkers offer hope for early detection of interstitial lung disease

Air pollution plays a significant role in the development of metabolic disorders

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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