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Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

In a recent study posted to the bioRxiv* preprint server, researchers test three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals authorized for emergency use by the United States Food and Drug Administration (FDA) for their in vitro potency against several SARS-CoV-2 variants, including the currently dominant Omicron train.

23 Jan 2022

Echinacea as a potential force against coronavirus infections

A new review identified clinical studies evaluating coronavirus infections in the context of Echinacea administration and assessed preventive and therapy advantages against COVID-19.

21 Jan 2022

Is COVID-19 mRNA vaccination in children associated with subsequent multisystemic hyper-inflammatory syndrome?

Researchers assessed the possibility of COVID-19 mRNA vaccines causing multisystem inflammatory syndrome in children aged 12 to 17 years in France.

20 Jan 2022

Females more prone to long-term post-COVID-19 symptoms

In a recent study published in the Journal of Clinical Medicine, researchers described the results of a multi-center study (LONG-COVID-EXP-CM) that investigated sex differences in coronavirus disease 2019 (COVID-19)-related symptoms and long-term post-COVID-19 symptoms in a group of previously hospitalized COVID-19 survivors in a large Spanish population.

19 Jan 2022

SARS-CoV-2 RNA can be detected in exhaled aerosol

In a study published in the open-access journal Influenza and other Respiratory Viruses, researchers investigated if severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be detected in exhaled aerosol samples obtained from coronavirus disease 2019 (COVID-19) patients during many different types of breathing and coughing. They also analyzed how SARS-CoV-2 infection may affect the size and number of exhaled aerosol particles.

19 Jan 2022

Exploring the interactions between multiple respiratory viruses

A recent report explores the dynamics of viral interference between various respiratory viruses in light of the ongoing COVID-19 pandemic.

19 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

SARS-CoV-2 Omicron has similar infectious viral load to Delta

Researchers compare SARS-CoV-2 pre-variants of concern strains to the Delta and Omicron VOCs.

16 Jan 2022

Study shows possible reverse zoonoses of SARS-CoV-2 from humans to animals

A new study describes an instance of natural infection of SARS-CoV-2 in a puma during the first wave and three lions during the third wave in a private zoo in South Africa in at least three transmission events from their handlers.

14 Jan 2022

Plasma SARS-CoV-2 viral RNA as a valuable biomarker for SARS-CoV-2 infection in the lungs

Researchers recently evaluated respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA (vRNA) levels in longitudinal samples collected simultaneously from mechanically ventilated coronavirus disease 2019 (COVID-19) patients and analyzed their connections and relationships with clinical outcomes.

13 Jan 2022

Microbial characteristics of COVID-19

To better understand how the disease progresses, a recent paper in the journal Frontiers in Medicine discusses the role of the human microbiota in this condition.

13 Jan 2022

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

In the present study, researchers isolated an infectious AY.4.2 strain of COVID-19 from the nasopharyngeal swab of a symptomatic individual from the Paris region. Then, they introduced the AY.4.2 signature mutations - T95I, Y145H, and A222V - in an expression plasmid coding the Delta protein to study the function of the AY.4.2 S protein.

13 Jan 2022

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

A new preprint describes a single-step molecular diagnostic test for the presence of SARS-CoV-2 infection caused by the Omicron variant that is behind the unprecedented rise in cases over the last few weeks.

11 Jan 2022

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available for free on the medRxiv* preprint server while it undergoes peer review.

9 Jan 2022

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

Researchers investigate the spread and transmission ability of SARS-CoV-2 lineages B.1.619 and B.1.620 in South Korea.

9 Jan 2022

SARS‑CoV‑2 Omicron variant escapes monoclonal antibodies

Researchers determine the neutralizing activity of four mAbs against ten strains of SARS-CoV-2.

9 Jan 2022

Levels of infectious SARS-CoV-2 in vaccinated and unvaccinated individuals

A new study assessed the levels of infectious virus (obtained from the nasopharynx) in vaccinated and unvaccinated individuals.

7 Jan 2022

Researchers isolate Omicron variant, leveling the path to vaccine development and vaccine efficacy studies

Researchers from India have now successfully grown and isolated the Omicron variant from hamsters in vivo with further culturing in the Vero CCL-81 cells in vitro, in a step forward towards testing the effectiveness of existing SARS-CoV-2 vaccines and generation of new Omicron appropriate vaccines.

7 Jan 2022

Researchers create new monoclonal antibody treatment effective against both Delta and Omicron

In a new study, researchers conducted surface plasmon resonance experiments using commercially sourced SARS-CoV-2 protein reagents.

6 Jan 2022

Emergence of a new SARS-CoV-2 variant from Southern France

A new study has described the emergence of another new SARS-CoV-2 variant from south-eastern France with Cameroonian origin.

6 Jan 2022

Nasopharyngeal News and Research

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

Echinacea as a potential force against coronavirus infections

Is COVID-19 mRNA vaccination in children associated with subsequent multisystemic hyper-inflammatory syndrome?

Females more prone to long-term post-COVID-19 symptoms

SARS-CoV-2 RNA can be detected in exhaled aerosol

Exploring the interactions between multiple respiratory viruses

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

SARS-CoV-2 Omicron has similar infectious viral load to Delta

Study shows possible reverse zoonoses of SARS-CoV-2 from humans to animals

Plasma SARS-CoV-2 viral RNA as a valuable biomarker for SARS-CoV-2 infection in the lungs

Microbial characteristics of COVID-19

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

Emerging SARS-CoV-2 B.1.619 and B.1.620 variants in South Korea

SARS‑CoV‑2 Omicron variant escapes monoclonal antibodies

Levels of infectious SARS-CoV-2 in vaccinated and unvaccinated individuals

Researchers isolate Omicron variant, leveling the path to vaccine development and vaccine efficacy studies

Researchers create new monoclonal antibody treatment effective against both Delta and Omicron

Emergence of a new SARS-CoV-2 variant from Southern France

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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