Peptides News and Research

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BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

A new study in the journal Viruses examines the phenomenon of breakthrough infections due to the evasion of T-cell immunity by the Omicron BA.4/BA.5 subvariants, showing this to be due to spike gene mutations.

2 Jan 2023

How could probiotics be used in the management of gingivitis and periodontitis?

New research explores how probiotic-based therapy in conjunction with established treatment regimens can be an effective approach for combating gingivitis and periodontitis.

28 Dec 2022

Researchers unravel how one of the crucial early steps on the path of life could have happened

One-hundred fifty years ago, Charles Darwin speculated that life likely originated in a warm little pond. There, Darwin supposed, chemical reactions and the odd lightning strike might have led to chains of amino acids that, over time, became more and more complex until the beginnings of life emerged.

21 Dec 2022

Review on nanoparticles usage for treating thrombosis induced by SARS-CoV-2 infections

Researchers provided an overview of nanomedicine strategies to treat coronavirus disease 2019 (COVID-19)-induced thrombosis.

21 Dec 2022

Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein

Researchers developed a measles virus (MeV)-vectored vaccine capable of inducing high neutralizing antibody (nAb) responses against SARS-CoV-2.

20 Dec 2022

Mild bee venom appears to be more usable for pharmacology

Honeybee venom has been used in traditional medicine for centuries as an anti-inflammatory. Only its main component, melittin, has been scientifically well researched.

20 Dec 2022

What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

Researchers assessed the impact of ceramide (CER) and cholesterol (CHOL) on membrane fusion mediated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

20 Dec 2022

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

Researchers described four novel monoclonal antibodies with potent and broad neutralization activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the current globally dominant Omicron BA.4/BA.5.

20 Dec 2022

mRNA vaccine methodologies: Production, value and spectrometer use

To be decided by the editor

From Thermo Fisher Scientific – Materials & Structural Analysis 16 Dec 2022

Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

Scientists identify an immunogenic epitope at the furin cleavage site of the SARS-CoV-2 spike protein.

15 Dec 2022

Radical project aims to develop a new method for commercial production of anti-microbial peptides

THE COVID pandemic has revealed just how delicate our public health is in terms of overcoming infectious diseases and antimicrobial resistance.

15 Dec 2022

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

In a recent study posted to bioRxiv*, researchers in the United States assessed the impact of metabolic diseases on coronavirus disease 2019 (COVID-19) vaccine immunogenicity in a mouse model.

13 Dec 2022

Study provides new insights for the future development of oral insulin pill

WEHI researchers in Melbourne have answered a 100-year-old question in diabetes research: can a molecule different to insulin have the same effect? The findings provide important insights for the future development of an oral insulin pill.

12 Dec 2022

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

Researchers construct a recombinant host-range restricted vaccinia virus Ankara (rMVAs) expressing the spike proteins of several SARS-CoV-2 variants.

11 Dec 2022

Immunopeptidome characters of human CoV-OC43-infected cells

Researchers explored T-cell epitopes derived from human seasonal coronavirus OC43.

5 Dec 2022

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers developed an mRNA technology-based vaccine candidate against the monkeypox virus and evaluated its immunogenicity in animal models.

5 Dec 2022

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Researchers elucidated pan-sarbecovirus immune protection mechanisms by utilizing a Venezuelan equine encephalitis virus-vectored vaccine panel that covered bat strains to human strains.

30 Nov 2022

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Recently, scientists reviewed the role of sulforaphane from cruciferous vegetables (e.g., broccoli) in preventing IBD by regulating inflammation and altering the gut microbiome.

29 Nov 2022

Does breast milk influence infants' intestinal microbiota?

A large number of health-related benefits of probiotics have led to the development of a new discipline called probiogenomics, which focuses on the molecular mechanisms of probiotic activities. According to the US Food and Drug Administration (FDA), the next-generation probiotics satisfy the scope of "live biotherapeutic products" (LBPs), which could be used to develop effective therapeutics for various diseases.

28 Nov 2022

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

In a recent study, researchers confirmed that feline coronavirus infection induced the production of cross-reactive antibodies against the SARS-CoV-2 receptor-binding domain in domestic cats.

28 Nov 2022

Peptides News and Research

BA.4/BA.5 mutations reduced responsiveness of epitope-specific T cells with original mRNA vaccine

How could probiotics be used in the management of gingivitis and periodontitis?

Researchers unravel how one of the crucial early steps on the path of life could have happened

Review on nanoparticles usage for treating thrombosis induced by SARS-CoV-2 infections

Researchers generate a remodeled live-attenuated measles vaccine capable of driving nAb responses against SARS-CoV-2 spike protein

Mild bee venom appears to be more usable for pharmacology

What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

mRNA vaccine methodologies: Production, value and spectrometer use

Scientists identify a novel epitope at the SARS-CoV-2 spike furin cleavage site

Radical project aims to develop a new method for commercial production of anti-microbial peptides

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

Study provides new insights for the future development of oral insulin pill

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

Immunopeptidome characters of human CoV-OC43-infected cells

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Does breast milk influence infants' intestinal microbiota?

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

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