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ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress.

11 Jun 2025

Methylation clocks may mislead anti-aging therapy evaluation

A new research perspective was published in Aging (Aging-US) Volume 17, Issue 5, on May 5, 2025, titled "Methylation clocks for evaluation of anti-aging interventions."

10 Jun 2025

Patient-derived xenograft models may become an indispensable tool in precision oncology

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many patients still face drug resistance and disease recurrence.

10 Jun 2025

Overexpression of two long non-coding RNAs identified in gastric cancer

A new research paper was published in Volume 16 of Genes & Cancer on May 9, 2025, titled "Evaluation of LncRNAs CBR3-AS1 and PCA3 expression in Gastric cancer and their correlation to clinicopathological variables."

6 Jun 2025

Reverse transcriptase activity found in aging and Alzheimer’s brains

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

Rethinking healthcare through the science of aging

A new editorial was published in Aging (Aging-US) Volume 17, Issue 5, on May 29, 2025, titled "Rethinking healthcare through aging biology."

4 Jun 2025

Aging increases brain vulnerability to mild hypoxia and blood-brain barrier disruption

A new research paper was published in Aging (Aging-US) on May 1, 2025, as the cover of Volume 17, Issue 5, titled "Defining the hypoxic thresholds that trigger blood-brain barrier disruption: the effect of age."

3 Jun 2025

Yeast cells offer promising alternative for manufacturing DNase1

The protein DNase1 is one of the oldest biological agents in history: It has been on the market since 1958 and is now used, among other things, to treat cystic fibrosis.

28 May 2025

Targeting individual frailty traits may prevent falls among the elderly

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 1, 2025, titled "Examining frailty phenotypes of community-dwelling older adults in Taiwan using the falls risk for older people in the community – Taiwan version (Tw-FROP-Com)."

23 May 2025

Rare cancer gene found in sperm donor sparks European regulatory concerns

A case in which a sperm donor was later found to be carrying a cancer-causing pathogenic variant in his gametes has highlighted the problems of regulating gamete donation at European and international level, the annual conference of the European Society of Human Genetics will hear today (Saturday).

23 May 2025

Detecting balance impairments early could prevent life-threatening falls

As we get older, our bodies stop performing as they once did. We aren't as strong as we once were, we don't see as well as we used to and we start becoming less mobile.

23 May 2025

Cutting back on sugary drinks may protect men’s fertility, review finds

Regular consumption of sugar-sweetened beverages is associated with lower sperm count, motility, and increased DNA damage, potentially impairing male reproductive health. This narrative review highlights dose-response effects, mechanisms, and research gaps, calling for further studies on diverse populations.

22 May 2025

Natural compounds from Brazilian plants show promise against stomach cancer

A new review was published in Volume 12 of Oncoscience on May 8, 2025, titled "The chemopreventive effects of native Brazilian plants on stomach cancer: A review of the last 25 years."

22 May 2025

Discovery unravels two populations of gonadotrophs in the pituitary gland

Researchers at the Francis Crick Institute have shown that gonadotrophs, cells in the pituitary gland with a key role in puberty and reproduction, come from two different populations, with the majority produced after birth rather than in the embryo, as previously thought.

21 May 2025