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Pancreatic cancer reprograms nerve cells to fuel growth

Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) in their current publication in Nature.

17 Feb 2025

Groundbreaking ALS platform trial accelerates research and drug testing

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with few treatment options. Since 2018, the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, has been working with national and international stakeholders to accelerate ALS research by launching the first platform trial in ALS to simultaneously test multiple drugs using shared trial infrastructure and placebo data.

17 Feb 2025

Icaritin softgel capsules offer new hope for hepatocellular carcinoma patients

Announcing a new publication for Acta Materia Medica journal. Icaritin (ICA) is a prenylflavonoid natural product extracted from plants of the Epimedium genus.

17 Feb 2025

Breakthrough computational tool enhances design of targeted antiviral therapies

Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication.

17 Feb 2025

New gene switch may lead to precise treatments for metabolic diseases

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

17 Feb 2025

Diabetes drugs may boost brain health but experts warn of risks

Researchers reviewed 374 studies to explore how GLP-1RAs, originally for diabetes, may impact brain health, finding potential benefits for dementia and addiction but inconsistent results for mood disorders.

16 Feb 2025

Prozac's surprising immune-boosting effects could lead to new treatments for sepsis

Antidepressants like Prozac are commonly prescribed to treat mental health disorders, but new research suggests they could also protect against serious infections and life-threatening sepsis.

14 Feb 2025

UVA receives $9.3 million NIH grant for ketamine seizure treatment trial

University of Virginia Brain Institute and School of Medicine researchers have received an initial $9.3 million award from the National Institutes of Health for a $30 million clinical trial to determine if the powerful anesthetic ketamine can save patients from prolonged, life-threatening grand mal seizures that won't respond to other treatments.

14 Feb 2025

Brain's opiate pathway triggers dessert cravings even after fullness

Who hasn't been there? The big meal is over, you're full, but the craving for sweets remains. Researchers from the Max Planck Institute for Metabolism Research in Cologne have now discovered that what we call the "dessert stomach" is rooted in the brain.

14 Feb 2025

Biohybrid hand with muscle tissue mimics real-life movements

A biohybrid hand which can move objects and do a scissor gesture has been built by a team at the University of Tokyo and Waseda University in Japan.

14 Feb 2025

Study reveals drastic variations in U.S. health care spending across counties

Researchers present the most comprehensive study on U.S. health care spending and variations across 3,110 counties by four payers, 148 health conditions, 38 age/sex groups, and seven types of care.

14 Feb 2025

Psychedelic treatments show promise for treating PTSD and depression

The Royal Devon University Healthcare NHS Foundation Trust is leading ground-breaking clinical research that has the potential to transform treatments for neuropsychiatric disorders.

14 Feb 2025

IgG-guided diet outperforms sham diet in clinical trial

Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the results of a blood test, compared to those who followed a sham elimination diet.

13 Feb 2025

Study reveals key mechanisms behind cancer cells adapting to extra chromosomes

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

13 Feb 2025

Gut bacteria could one day serve as microscopic in-house pharmacists

Hundreds of different species of microbes live, laugh, and love in your gut. In the future, one of these might serve a new function: microscopic in-house pharmacist.

13 Feb 2025

Immunocompromised individuals need regular boosters for Covid-19 protection

Vaccinations alone may not be enough to protect people with compromised immune systems from infection, even if the vaccine has generated the production of antibodies, new research from the University of Cambridge has shown.

13 Feb 2025

Postpartum depression research could lead to blood test for at-risk women

New postpartum depression research from the University of Virginia School of Medicine and Weill Cornell Medicine could lead to a blood test to identify women at risk and possibly even to a preventive treatment.

13 Feb 2025

Study breaks down Alzheimer's treatment effects in clear terms

In the past two years, the Food and Drug Administration has approved two novel Alzheimer's therapies, based on data from clinical trials showing that both drugs slowed the progression of the disease.

13 Feb 2025

Selkirk Pharma introduces ClinFAST™ to expedite fill/finish for clinical trials

Selkirk Pharma, Inc., a privately held U.S. pharmaceutical manufacturer specializing in the fill and finish of injectable drugs, including vaccines and biological therapeutics, today announced the launch of ClinFAST™, a paradigm-shifting service designed to assist clinical stage biotech and pharma companies with a rapid fill/finish process for clinical trial supplies.

13 Feb 2025