Gene Expression News and Research

RSS

Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Study shows how CD4+ T cells respond to SARS-CoV-2 virus

As scientists around the world develop life-saving COVID-19 vaccines and therapies, many are still wondering exactly why the disease proves deadly in some people and mild in others.

7 Oct 2020

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

A new study published on the preprint server bioRxiv* aimed to investigate the impacts of COVID-19 on people with various illnesses. Specifically, the researchers at the Rockefeller Cancer Institute, and the University of Arkansas for Medical Sciences wanted to see the effects of COVID-19 on patients with cancer and other infectious diseases.

6 Oct 2020

CAR T cell therapy can predict treatment response in patients with large B-cell lymphoma

Researchers at The University of Texas MD Anderson Cancer Center have identified molecular and cellular characteristics of anti-CD19 CAR T cell infusion products associated with how patients with large B-cell lymphoma (LBCL) respond to treatment and develop side effects.

6 Oct 2020

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

6 Oct 2020

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

A recent paper published in the preprint server medRxiv in September 2020 discusses the “clinically relevant variation in the expression of COVID-19-related genes”, which is associated with the host and environmental factors, as well as host genetic factors.

6 Oct 2020

Stud shows possibility for regenerating neurons in the eye and brain

The death of neurons, whether in the brain or the eye, can result in a number of human neurodegenerative disorders, from blindness to Parkinson's disease. Current treatments for these disorders can only slow the progression of the illness, because once a neuron dies, it cannot be replaced.

5 Oct 2020

Ludwig study uncovers a nutritional approach to improve cancer immunotherapy

A Ludwig Cancer Research study has uncovered a mechanism by which the tumor's harsh internal environment sabotages T lymphocytes, leading cellular agents of the anticancer immune response.

5 Oct 2020

Direction and type of the force acting on a cell can alter gene expression

Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few.

1 Oct 2020

$9.1 million NCI grant renewal will support researchers studying retrovirus cancer models

The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and The Ohio State University College of Veterinary Medicine have been awarded a five-year, $9.1 million grant Program Project Grant renewal from the National Cancer Institute.

1 Oct 2020

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

30 Sep 2020

Small for gestational age babies more likely to experience asymmetric growth

Carrying a fetus that is small for gestational age is associated with increased rates of stillbirth and neonatal death as well as metabolic disease in later life.

30 Sep 2020

Simple interactions between nerve cells can shape complex brain circuits

Complex brain circuits in rodents can organize themselves with genetics playing only a secondary role, according to a new computer modelling study published today in eLife.

30 Sep 2020

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology.

30 Sep 2020

A study contradicting the phenotypical relationship between plasmablasts and developing neutrophils

A team of scientists from Australia challenges the findings of a recent study by Wilk et al. demonstrating that plasmablasts transdifferentiate into developing neutrophils in severe coronavirus disease 2019 (COVID-19). The Australian study is currently available on the bioRxiv preprint server.

29 Sep 2020

Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020

Life-threatening COVID-19 associated with specific genetic variants

Results of a genome-wide association study on 2,244 critically-ill patients due to coronavirus disease (COVID-19) from 208 intensive care units across the United Kingdom revealed significant host-specific genetic determinants that can predispose people to the severe form of the disease. The report is currently available on the medRxiv preprint server.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Scientists identify a new way to regulate cell plasticity

Cell plasticity is a property by which a cell can take on different and reversible identities. Cell plasticity is also essential for embryo development and for the correct function of the immune system.

28 Sep 2020

New suite of human blood biomarkers can improve stroke diagnosis

An interdisciplinary group of researchers at the Frances Payne Bolton School of Nursing at Case Western Reserve University have uncovered a new suite of human blood biomarkers which could someday help emergency clinicians quickly recognize whether someone is experiencing a stroke with a simple blood test.

25 Sep 2020

New tool enables big data analysis without specialized expertise in bioinformatics

A new data analysis tool developed by researchers at The University of Texas MD Anderson Cancer Center incorporates a user-friendly, natural-language interface to allow biomedical researchers without specialized expertise in bioinformatics or programming languages to conduct intuitive analysis of large datasets.

25 Sep 2020

Gene Expression News and Research

Further Reading

Study shows how CD4+ T cells respond to SARS-CoV-2 virus

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

CAR T cell therapy can predict treatment response in patients with large B-cell lymphoma

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

Stud shows possibility for regenerating neurons in the eye and brain

Ludwig study uncovers a nutritional approach to improve cancer immunotherapy

Direction and type of the force acting on a cell can alter gene expression

$9.1 million NCI grant renewal will support researchers studying retrovirus cancer models

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Small for gestational age babies more likely to experience asymmetric growth

Simple interactions between nerve cells can shape complex brain circuits

Blocking the self-destruction process of enzymes can mitigate age-related diseases

A study contradicting the phenotypical relationship between plasmablasts and developing neutrophils

Valproic acid can interact with DNA conformation and regulate gene expression

Life-threatening COVID-19 associated with specific genetic variants

Epigenetic changes in the brain drive late-onset Alzheimer's disease

Scientists identify a new way to regulate cell plasticity

New suite of human blood biomarkers can improve stroke diagnosis

New tool enables big data analysis without specialized expertise in bioinformatics

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®