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Redhill Biopharma announces completion of Phase 2/3 COVID-19 study of oral opaganib

RedHill Biopharma Ltd., a specialty pharma company that is a leader in the development of novel oral therapies for COVID-19, today announced that all treatment and follow-up has now been completed in the 475-patient global Phase 2/3 study with opaganib (ABC294640) in patients hospitalized with severe COVID-19 pneumonia (NCT04467840). Top-line results are expected in the coming weeks.

20 Jul 2021

Same-day screening and health education program seeks to reduce disparities of preventable cancers

Evidence shows that early detection and treatment of cancer can significantly improve health outcomes, however women in Mississippi, particularly in underserved populations, experience the worst health outcomes for cervical, breast, and oropharyngeal cancer.

20 Jul 2021

Iodine derivative kills SARS-CoV-2 within 90 sec

A recent study estimated the virucidal efficacy of EID for oral/nasal decontamination of known or suspected cases of COVID-19.

19 Jul 2021

T cells can be engineered to fight tumors without succumbing to exhaustion

Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.

19 Jul 2021

Oral prodrug delivers carbon monoxide to protect against acute kidney injury

An oral prodrug developed by a team of scientists led by Binghe Wang, Regents' Professor of Chemistry at Georgia State University, delivers carbon monoxide to protect against acute kidney injury, according to a new paper published in Chemical Science.

19 Jul 2021

Broad-spectrum antibiotic no more effective than placebo in preventing COVID-19 symptoms

A UC San Francisco study has found that the antibiotic azithromycin was no more effective than a placebo in preventing symptoms of COVID-19 among non-hospitalized patients, and may increase their chance of hospitalization, despite widespread prescription of the antibiotic for the disease.

16 Jul 2021

Pandemic disrupted the utilization of women’s preventive health services

The COVID-19 pandemic knocked many women off schedule for important health appointments, a new study finds, and many didn't get back on schedule even after clinics reopened. The effect may have been greatest in areas where such care is already likely falling behind experts' recommendations.

16 Jul 2021

India's Mission Indradhanush improves vaccination outcomes for children

Researchers at CDDEP recently published 'Improving vaccination coverage and timeliness through periodic intensification of routine immunization: evidence from Mission Indradhanush' where they evaluated the performance of India's Mission Indradhanush (MI) child vaccination campaign -- a periodic intensification of the routine immunization program.

16 Jul 2021

$50,000 grant to help explore the use of turmeric for reducing joint pain in breast cancer patients

UC Davis Comprehensive Cancer Center received a $50,000 grant from the Safeway Foundation to explore the use of the South Asian spice Turmeric as a way of reducing joint pain in breast cancer patients being treated with anti-estrogen drugs.

16 Jul 2021

Study: Adolescent girls and young women can and will use HIV prevention products with consistency

Adolescent girls and young women can and will use HIV prevention products with consistency, according to interim results of a study of two different methods: daily use of the antiretroviral (ARV) tablet Truvada as oral pre-exposure prophylaxis (PrEP) and the monthly dapivirine vaginal ring, a new HIV prevention product currently under regulatory review in several countries.

15 Jul 2021

Study sheds new light on why some people may be more prone to serious gum infection

A team led by University of Washington researchers has, for the first time, identified and classified how different people respond to the accumulation of dental plaque, the sticky biofilm that gathers on teeth.

14 Jul 2021

Dying patients with rare diseases struggle to get experimental therapies

At 15, Autumn Fuernisen is dying. She was diagnosed at age 11 with a rare degenerative brain disorder that has no known cure or way to slow it down: juvenile-onset Huntington's disease.

14 Jul 2021

New study finds an association between alcohol use and higher risk of several cancers

A new study from the World Health Organization's International Agency for Research on Cancer (IARC), published in the journal Lancet Oncology, has found an association between alcohol and a substantially higher risk of several forms of cancer, including breast, colon, and oral cancers.

14 Jul 2021

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel, highly infectious respiratory virus, and the causative agent of coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2, which first originated in Wuhan, in Hubei province of China, is a member of the Coronavirdae family and has a large, non-segmented RNA genome.

14 Jul 2021

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

Researchers in the United States have provided a high-resolution description of the viral dynamics involved in acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

14 Jul 2021

HIV research center set up in the UK to address health inequalities and develop new treatments

A trailblazing HIV research center is being set up in the UK to address health inequalities and improve quality of life for everyone affected by HIV.

12 Jul 2021

Can saliva metabolomics predict COVID-19 severity?

New research suggests that saliva metabolomics may be able to help prognosticate disease severity in COVID-19 positive individuals.

9 Jul 2021

SARS-CoV-2 antibody testing in oral fluids may be an efficient way forward for research in children

A recent study by researchers from the United Kingdom (UK) and Brazil shows how laboratory assays based on the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in oral fluids can be used as a suitable tool for population-based seroepidemiology studies in children. The paper is currently available on the medRxiv* preprint server while it undergoes peer review.

8 Jul 2021

Enzyme inhibitor boosts immune system to fight MRSA and other dangerous skin infections

In what turned out to be one of the most important accidents of all time, Scottish bacteriologist Alexander Fleming returned to his laboratory after a vacation in 1928 to find a clear zone surrounding a piece of mold that had infiltrated a petri dish full of Staphylococcus aureus (S. aureus), a common skin bacterium he was growing.

8 Jul 2021

Researchers discover how to artificially produce healthy mucus

Many people instinctively associate mucus with something disgusting, but in fact, it has incredibly many valuable functions for our health. It keeps track of our important intestinal flora and feeds the bacteria.

8 Jul 2021

Oral News and Research

Redhill Biopharma announces completion of Phase 2/3 COVID-19 study of oral opaganib

Same-day screening and health education program seeks to reduce disparities of preventable cancers

Iodine derivative kills SARS-CoV-2 within 90 sec

T cells can be engineered to fight tumors without succumbing to exhaustion

Oral prodrug delivers carbon monoxide to protect against acute kidney injury

Broad-spectrum antibiotic no more effective than placebo in preventing COVID-19 symptoms

Pandemic disrupted the utilization of women’s preventive health services

India's Mission Indradhanush improves vaccination outcomes for children

$50,000 grant to help explore the use of turmeric for reducing joint pain in breast cancer patients

Study: Adolescent girls and young women can and will use HIV prevention products with consistency

Study sheds new light on why some people may be more prone to serious gum infection

Dying patients with rare diseases struggle to get experimental therapies

New study finds an association between alcohol use and higher risk of several cancers

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

HIV research center set up in the UK to address health inequalities and develop new treatments

Can saliva metabolomics predict COVID-19 severity?

SARS-CoV-2 antibody testing in oral fluids may be an efficient way forward for research in children

Enzyme inhibitor boosts immune system to fight MRSA and other dangerous skin infections

Researchers discover how to artificially produce healthy mucus

Industry Focus eBook - Cell biology (5th edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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