Therapeutics News and Research

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Researchers demonstrate the role of Klotho protein in the formation of osteoarthritis

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity.

10 Jan 2023

Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

Vector BioPharma and iBET collaborate to develop high-throughput analytical methods and scalable processes for gene delivery

Collaboration set to develop and implement high-throughput analytical methods in support of Vector BioPharma’s CMC (chemistry, manufacturing and controls) development.

From Vector BioPharma 10 Jan 2023

Ubiquigent appoints Dr Xavier Jacq to Scientific Advisory Board

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced the appointment of Dr Xavier Jacq to its Scientific Advisory Board (SAB).

10 Jan 2023

Detailed molecular profile of endometriosis can lead to improved care for millions of women

Investigators at Cedars-Sinai have created a unique and detailed molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

9 Jan 2023

Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

UBC researchers have identified three compounds that prevent COVID-19 infection in human cells, derived from natural sources including a B.C. sea sponge.

9 Jan 2023

Novel T cell receptor therapy shows early promise for treating solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

9 Jan 2023

Newly identified gene drives development of the second most common type of lung carcinoma

A team led by researchers at NYU Langone Health's Perlmutter Cancer Center has identified a gene that drives development of the second most common type of lung carcinoma, offering greater insight into how the disease might someday be treated.

9 Jan 2023

New model for detecting and estimating pathogen variant dynamics and risk

A recent study posted to the medRxiv* preprint server developed a hierarchical modeling method to estimate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant fitness advantage and prevalence.

8 Jan 2023

Low-cost intervention can make a difference to America's deadly overdose epidemic

There are no simple solutions to America's deadly overdose epidemic, which costs 100,000 lives each year and is erasing gains in life expectancy.

6 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

High affinity antibodies isolated to safely target Claudin 6-positive tumors

Integral Molecular, the industry leader in antibody discovery for membrane proteins, has published the targeting mechanism enabling best-in-class specificity of its Claudin 6 (CLDN6) antibody CTIM-76 being developed for cancer therapy with Context Therapeutics.

6 Jan 2023

Cerba Research is officially a member of Hong Kong Bio-Med Innotech Association (HKBMIA)

Cerba Research announces membership of HKBMIA to act as an advisor on speciality testing and routine clinical trials testing to advance research and health while supporting Asia pacific healthcare companies develop new therapeutics.

From Cerba Research 6 Jan 2023

Study describes the variations in drug response across genetic subtypes of childhood leukemia

Scientists at St. Jude Children's Research Hospital are reporting the most comprehensive study to date describing the variations in drug response across different genetic subtypes of acute lymphoblastic leukemia (ALL).

5 Jan 2023

Research findings open the door to new strategies for promoting muscle function during aging

Proven to protect against a wide array of diseases, exercise may be the most powerful anti-aging intervention known to science.

5 Jan 2023

Researchers reveal previously unknown properties of T cells

Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz Institute for Natural Product Research and Infection Biology and an international research team discovered.

5 Jan 2023

Sugar appears to play a role in polycystic kidney disease, study finds

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

5 Jan 2023

Latest discovery provides new understanding of the fundamental mechanics of the human brain

From the complexity of neural networks to basic biological functions and structures, the human brain only reluctantly reveals its secrets.

5 Jan 2023

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Insilico Medicine, a clinical stage, end-to-end artificial intelligence (AI)-driven drug discovery company, held the launch ceremony for Life Star – a 6th generation Intelligent Robotics Drug Discovery Laboratory – in Suzhou BioBAY Industrial Park on Dec. 29.

5 Jan 2023

Orbit Discovery and SanegeneBio collaborate to identify targeting peptides for RNAi drugs

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From Orbit Discovery 5 Jan 2023

Therapeutics News and Research

Researchers demonstrate the role of Klotho protein in the formation of osteoarthritis

Researchers review bacteriophage treatment

Vector BioPharma and iBET collaborate to develop high-throughput analytical methods and scalable processes for gene delivery

Ubiquigent appoints Dr Xavier Jacq to Scientific Advisory Board

Detailed molecular profile of endometriosis can lead to improved care for millions of women

Compounds derived from B.C. sea sponge can prevent COVID-19 infection in human cells

Novel T cell receptor therapy shows early promise for treating solid tumors

Newly identified gene drives development of the second most common type of lung carcinoma

New model for detecting and estimating pathogen variant dynamics and risk

Low-cost intervention can make a difference to America's deadly overdose epidemic

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

High affinity antibodies isolated to safely target Claudin 6-positive tumors

Cerba Research is officially a member of Hong Kong Bio-Med Innotech Association (HKBMIA)

Study describes the variations in drug response across genetic subtypes of childhood leukemia

Research findings open the door to new strategies for promoting muscle function during aging

Researchers reveal previously unknown properties of T cells

Sugar appears to play a role in polycystic kidney disease, study finds

Latest discovery provides new understanding of the fundamental mechanics of the human brain

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Orbit Discovery and SanegeneBio collaborate to identify targeting peptides for RNAi drugs

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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