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Scientists unravel mystery of how immune cells remember infections decades later

A perplexing question in immunology has been, how do immune cells remember an infection or a vaccination so that they can spring into action decades later? Research led by scientists at the University of California, Berkeley, in collaboration with investigators at Emory University, has found an answer: A small pool of the same immune cells that responded to the original invasion remain alive for years, developing unique features that keep them primed and waiting for the same microbe to re-invade the body.

14 Dec 2017

Muscle paralysis may promote breakdown of bones

Muscle paralysis rapidly causes inflammation in nearby bone marrow, which may promote the formation of large cells that break down bone, a new study finds.

14 Dec 2017

IU scientists discover way to make drug treatment more successful against malaria

Indiana University School of Medicine researchers have identified a way to block the ability of parasites that cause malaria to shield themselves against drug treatments in infected mice--a finding that could lead to the development of new approaches to combat this deadly disease in humans.

14 Dec 2017

Studies reveal possibility for memory T cells to serve a dual purpose

Scientists of two new complementary studies researching mice and humans claim that they have the strongest evidence yet that memory T cells responsible for long-term immune protection also serve an additional role.

14 Dec 2017

Study finds social stigma as barrier to successful treatment of children with HIV in Ethiopia

The social stigma surrounding HIV is still strong in many parts of the world. Children living with HIV in Ethiopia are at high risk of receiving inadequate treatment - or no treatment at all - on account of deeply rooted prejudice.

14 Dec 2017

New blood test accurately forecasts advanced heart failure patients’ survival after surgery

An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for people with advanced heart failure who had surgery to implant mechanical circulatory support devices.

14 Dec 2017

Human ‘common cold’ virus kills healthy chimpanzees in Uganda

In the wild, chimpanzees face any number of dire threats, ranging from poachers to predators to deforestation.

13 Dec 2017

Steroid study provides new insights into medicines' side effects

Fresh insights into key hormones found in commonly prescribed medicines have been discovered, providing further understanding of the medicines' side effects.

13 Dec 2017

Belgian researchers create transplantable artificial ovary prototype

Belgian researchers have taken important steps towards creating transplantable artificial ovaries. Once successful, these could be of value to women struggling with infertility or cancer patients who cannot conceive after undergoing radiation or chemotherapy.

13 Dec 2017

Protein structure could pave way for effective drugs to treat cystic fibrosis

Biochemists at the University of Zurich have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a promising target for the development of effective drugs to treat cystic fibrosis.

13 Dec 2017

Researchers develop biosensor that enables development of new health tests

Researchers at Aalto University, Finland, have developed a biosensor that enables creating a range of new easy-to-use health tests similar to home pregnancy tests.

13 Dec 2017

Study finds barriers to stem cell transplant use among multiple myeloma patients from minority groups

A study by researchers at Mayo Clinic's campus in Jacksonville, Florida has found that barriers to patients receiving stem cell therapy as part of their treatment for multiple myeloma include income, education, insurance status and access to care at an academic center or facility that treats a high volume of patients.

13 Dec 2017

Study reveals impact of diabetes during pregnancy on baby's heart

A new study conducted at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA discovered how increased glucose levels caused either by diabetes or other factors keep heart cells from maturing normally.

13 Dec 2017

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Inflammatory bowel disease (IBD), including the two conditions ulcerative colitis and Crohn's disease, results in long-term inflammation of the gut and is associated with dysregulation of the immune system.

13 Dec 2017

Study provides new insights into development of Sonic Hedgehog medulloblastoma

Medulloblastoma is the most common type of solid brain tumor in children. Current treatments offer limited success and may leave patients with severe neurological side effects, including psychiatric disorders, growth retardation and cognitive impairment.

13 Dec 2017

Researchers adopt new approach to treating advanced prostate cancer

Scientists have proposed a new approach to preventing the proliferation of prostate tumor cells that are no longer responding to treatment. Prostate cancer can usually be cured via surgical removal of the tumor and/or the use of radiotherapy, but in one-fifth of cases, patients also require treatment with drugs to continue removing tumor cells. However, these drugs are only effective for up to three years, after which the cancer continues to develop.

13 Dec 2017

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

Scientists develop new, high resolution method for identifying microbial species and strains

Scientists from the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions New York University and the University of Florida today published a report detailing their new, more accurate method for identifying individual microbial species and strains in a community.

13 Dec 2017

Mitochondrial error-correction mechanism essential for energy production of cells

Mitochondria generate most of the energy cells need through a respiratory chain for which they must produce their own proteins.

13 Dec 2017

Researchers take step toward using man-made nanoscale compounds to fight cancer

Researchers in Sweden have succeeded in taking the next step toward using man-made nanoscale compounds in the fight against cancer.

13 Dec 2017

B Cell News and Research

Scientists unravel mystery of how immune cells remember infections decades later

Muscle paralysis may promote breakdown of bones

IU scientists discover way to make drug treatment more successful against malaria

Studies reveal possibility for memory T cells to serve a dual purpose

Study finds social stigma as barrier to successful treatment of children with HIV in Ethiopia

New blood test accurately forecasts advanced heart failure patients’ survival after surgery

Human ‘common cold’ virus kills healthy chimpanzees in Uganda

Steroid study provides new insights into medicines' side effects

Belgian researchers create transplantable artificial ovary prototype

Protein structure could pave way for effective drugs to treat cystic fibrosis

Researchers develop biosensor that enables development of new health tests

Study finds barriers to stem cell transplant use among multiple myeloma patients from minority groups

Study reveals impact of diabetes during pregnancy on baby's heart

Researchers suggest role for MKL1 protein in development of inflammatory bowel disease

Study provides new insights into development of Sonic Hedgehog medulloblastoma

Researchers adopt new approach to treating advanced prostate cancer

Researchers discover new way to attack drug-resistant prostate cancer cells

Scientists develop new, high resolution method for identifying microbial species and strains

Mitochondrial error-correction mechanism essential for energy production of cells

Researchers take step toward using man-made nanoscale compounds to fight cancer

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