Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Researchers identify transferrin as potential contributor to COVID-19 severity

SARS-CoV-2 is the coronavirus that causes COVID-19. It is currently not known why some individuals develop only mild or no symptoms when infected, whilst others experience severe, life-threatening forms of the disease.

3 Aug 2020

Researchers develop new therapeutic approach to treat CLN3 Batten disease

Researchers led by a team at Rosalind Franklin University of Medicine and Science have devised a new therapeutic approach to treating a rare but deadly neurodegenerative genetic disease in children.

31 Jul 2020

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

Grants totaling nearly $3.5 million give early career investigators independence to pursue brave and bold cancer research.

31 Jul 2020

German researchers present new brain atlas in the Science journal

The atlas features close to 250 structurally distinct areas, each one based on the analysis of 10 brains. More than 24000 extremely thin brain sections were digitized, assembled in 3D and mapped by experts.

31 Jul 2020

Smoking worsens COVID-19 severity, warn researchers

A study conducted by researchers at the University of California, Los Angeles, suggests that smoking increases the risk of more severe lung disease in cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

30 Jul 2020

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

The reactivation of telomerase is a key mechanism in the unrestricted growth of cancer cells. Malignant pleural mesothelioma (MPM) is a form of cancer originating from the mesothelium, a cell layer covering the lungs and the inside of the chest wall.

30 Jul 2020

Researchers are developing comprehensive catalog of functional elements of human and mouse genomes

Scientists around the world have access to a rich trove of information through the Encyclopedia of DNA Elements (ENCODE)--annotated versions of the human and mouse genomes that are vital for interpreting their genetic codes.

30 Jul 2020

Experts caution against routine use of current GEP tests for melanoma patients

A consensus statement published today in JAMA Dermatology by an international group of melanoma researchers evaluates the use of prognostic genetic expression profile (GEP) testing to guide clinical management of patients with melanoma.

29 Jul 2020

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA--called methylation--in developing mice.

29 Jul 2020

Deep learning algorithm can identify genetic alterations from routine histological images of tumors

Researchers at the University of Chicago Medicine Comprehensive Cancer Center, working with colleagues in Europe, created a deep learning algorithm that can infer molecular alterations directly from routine histology images across multiple common tumor types.

28 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

28 Jul 2020

Researchers identify a miRNA that could promote hair regeneration

Researchers from North Carolina State University have identified a microRNA (miRNA) that could promote hair regeneration.

27 Jul 2020

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

27 Jul 2020

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

In a recent bioRxiv* study, UK researchers used interleukin modules to investigate the pathology of coronavirus disease (COVID-19).

27 Jul 2020

Olfactory cell types are most vulnerable to COVID-19 infection, shows study

Temporary loss of smell, or anosmia, is the main neurological symptom and one of the earliest and most commonly reported indicators of COVID-19.

25 Jul 2020

New model may explain why certain cancer cells are resistant to therapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures.

24 Jul 2020

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person.

22 Jul 2020

Researchers identify specific target sites for DNA methylases

DNA methylation performs an essential function in mammalian ontogeny. It is also known that abnormalities in this process cause the development of cancers such as leukemia.

22 Jul 2020

Gene Expression News and Research

Further Reading

Researchers identify transferrin as potential contributor to COVID-19 severity

Researchers develop new therapeutic approach to treat CLN3 Batten disease

15 young scientists receive Damon Runyon Fellowship Award to pursue cancer research

German researchers present new brain atlas in the Science journal

Smoking worsens COVID-19 severity, warn researchers

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

Researchers are developing comprehensive catalog of functional elements of human and mouse genomes

Experts caution against routine use of current GEP tests for melanoma patients

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

Deep learning algorithm can identify genetic alterations from routine histological images of tumors

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

Researchers identify a miRNA that could promote hair regeneration

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

Olfactory cell types are most vulnerable to COVID-19 infection, shows study

New model may explain why certain cancer cells are resistant to therapy

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Researchers identify specific target sites for DNA methylases

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