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Rare transition metal can simplify design and preparation of antibody therapies

Rice University scientists have developed a method to efficiently modify natural antibodies that can deliver drugs to target cells. Adding a little extra metal is the key.

24 Aug 2017

Study may lead to new therapy options for treatment resistant, relapsed endometrial cancer

A team of Cleveland Clinic researchers have discovered a key pathway that leads to recurrence and treatment resistance in endometrial cancer, providing the potential for much needed new therapies for women with limited options.

24 Aug 2017

Bacterial infections may trigger dysregulation of blood formation

It has been thought that only immune cells would act as the line of defense during bacterial infection. However, recent research has revealed that hematopoietic stem cells, cells that create all other blood cells throughout an individual's lifetime, are also able to respond to the infection.

24 Aug 2017

Study finds ethylene release in exhaled breath as early biomarker of bacterial infection

Although ethylene (or ethene) is best known as a plant hormone, humans also produce it as consequence of oxidative stress, caused for example by the UV radiation from the sun.

24 Aug 2017

Researchers identify important adenovirus receptor in macrophages of mice

Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people.

24 Aug 2017

DNA sensor systems provide highly sensitive monitoring of cancer-related enzyme activity

The development of DNA sensor systems is of great importance for advances in medical science. Now another piece of the puzzle for the development of personalized medicine has been found with the results of a highly sensitive monitoring of cancer-related topoisomerase II enzymes.

24 Aug 2017

New strategy allows researchers to identify potential treatments for altered levels of MeCP2

Having twice the normal amount of the protein MeCP2, a condition called MECP2 duplication syndrome, causes severe progressive neuropsychiatric disorders that include intellectual disability, autism spectrum disorders, motor dysfunction and other medical complications.

24 Aug 2017

Study of ticks and tick-borne diseases receive global boost

A unique scientific resource for the study of ticks and tick-borne diseases has moved to the University of Liverpool with exciting plans for international expansion.

24 Aug 2017

Researchers uncover how mutations in single gene lead to rare kidney and liver disease

In a joint international study, researchers from Osaka University have partnered with research groups from the United States and Spain to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease, ARPKD (autosomal recessive polycystic kidney disease).

24 Aug 2017

Scientists uncover stem cell response to prolonged irradiation

Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells.

24 Aug 2017

Study shows role of exhausted regulatory T cells in allergic reactions

Researchers have evidence that the specialized T cells responsible for maintaining a balanced immune response are vulnerable to exhaustion that disrupts normal functioning and may even contribute to allergic reactions.

23 Aug 2017

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

Mitochondria, the tiny structures inside our cells that generate energy, may play a key role in autism spectrum disorders (ASD).

23 Aug 2017

Researchers compare effectiveness of natural and synthetic materials for dental pulp tissue engineering

To regenerate dental pulp tissue after emptying of a tooth's root canals researchers compared the effectiveness of 3D scaffolds made of natural or customized synthetic materials containing pulpal stem cells and dentin-derived growth factors.

23 Aug 2017

New international research project identifies subtypes of ocular melanoma

A new international research project, involving the University of Liverpool's leading eye cancer research group, has identified specific subtypes of ocular melanoma that will help develop improved management strategies and therapies in the future.

23 Aug 2017

USC scientist finds new approach to prevent HIV infection

Medical treatment that targets human proteins rather than ever-mutating viruses may one day help HIV-positive people whose bodies have built a resistance to "cocktails" currently used to keep them healthy, according to a Keck School of Medicine of USC researcher.

23 Aug 2017

New research aims to generate in vitro vascularized pancreatic islets from hPSCs

Tiny packets of cells called islets throughout the pancreas allow the organ to produce insulin. Type 1 diabetes -- also known as juvenile diabetes - tricks the immune system into destroying these islets.

23 Aug 2017

Study findings could one day help doctors better predict survival of liver cancer patients

A new study of a molecule that regulates liver-cell metabolism and suppresses liver-cancer development shows that the molecule interacts with thousands of genes in liver cells, and that when levels of the molecule go down, which often happens during liver-cancer development, the activity of certain cancer-promoting genes goes up.

23 Aug 2017

B Cell News and Research

Rare transition metal can simplify design and preparation of antibody therapies

Study may lead to new therapy options for treatment resistant, relapsed endometrial cancer

Bacterial infections may trigger dysregulation of blood formation

Study finds ethylene release in exhaled breath as early biomarker of bacterial infection

Researchers identify important adenovirus receptor in macrophages of mice

DNA sensor systems provide highly sensitive monitoring of cancer-related enzyme activity

New strategy allows researchers to identify potential treatments for altered levels of MeCP2

Study of ticks and tick-borne diseases receive global boost

Researchers uncover how mutations in single gene lead to rare kidney and liver disease

Scientists uncover stem cell response to prolonged irradiation

Study shows role of exhausted regulatory T cells in allergic reactions

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

Researchers compare effectiveness of natural and synthetic materials for dental pulp tissue engineering

New international research project identifies subtypes of ocular melanoma

USC scientist finds new approach to prevent HIV infection

New research aims to generate in vitro vascularized pancreatic islets from hPSCs

Study findings could one day help doctors better predict survival of liver cancer patients

Blood cleaning device can also effectively provide a bridge to liver transplantation

Our body contains more diverse microbes than previously known, new survey suggests

Researchers pursuing new approach to treating arthritis

Using single B cell screening to boost antibody discovery eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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