Fluorescence News and Research

RSS

Advanced imaging techniques shed light on single cells

Every plant, animal, and person is a rich microcosm of tiny, specialized cells. These cells are worlds unto themselves, each with their own unique parts and processes that elude the naked eye.

2 Aug 2024

Novel electrical impedance technique enhances drug testing for cardiac safety

When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical.

1 Aug 2024

Researchers develop highly reactive RNA building blocks for enhanced chip production

An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient. The results of the research were recently published in the prestigious journal Science Advances.

1 Aug 2024

Medline to offer first ever FDA-cleared, point-of-care fentanyl urine screening kit on RYAN™ analyzer

Carolina Liquid Chemistries Corp. (CLC) has entered into a distribution agreement with Medline Industries, LP (Medline) to make the first ever FDA-cleared, point-of-care fentanyl screening test kit readily available to many point-of-care sites and clinical laboratories across the United States of America.

1 Aug 2024

Breakthrough X-ray-sensitizers could revolutionize radiotherapy for cancer patients

Researchers at Xiamen University have made a significant advancement in cancer treatment by developing a novel class of X-ray-sensitizers (XSs) that could revolutionize radiotherapy.

31 Jul 2024

New discovery unveils key process in DNA repair pathway

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of Molecular Biology (LMB) in Cambridge, has solved a decades-old mystery which could pave the way to better cancer treatments in the future.

31 Jul 2024

Exosome-encapsulated fluorescent sensors enable advanced brain imaging in Alzheimer's research

Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's.

31 Jul 2024

High-resolution brain maps reveal vascular blueprint for healthy aging

Healthy blood vessels matter for more than just heart health. Vascular well-being is critical for brain health and potentially in addressing age-related cognitive decline and neurodegenerative disorders, like Alzheimer's disease, according to new study led by Penn State researchers. The findings point to an understudied but possible key role the brain's vascular network - or energy infrastructure - plays in the onset of neurodegenerative disease.

31 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Revolutionizing hepatocyte count for researchers

In this interview, NewsMedical speaks to DeNovix's Dan Schieffer about the new app developed for CellDrop, and how it aims to revolutionize hepatocyte count for the drug discovery industry, and more.

From DeNovix Inc. 29 Jul 2024

Waters new Rapid Screening-DSC enables up to 24x faster thermal stability testing at ultra-low sample volumes for antibody drugs

Waters Corporation announced today the global release of the TA Instruments™ Rapid Screening-Differential Scanning Calorimeter (TA Instruments RS-DSC), designed for biopharmaceutical developers. The TA Instruments RS-DSC is a high-throughput DSC for precise thermal stability testing of high-concentration biologic formulations specifically for antibody drugs and engineered proteins

From TA Instruments 24 Jul 2024

Multiplexed STED nanoscopy technique reduces photobleaching and phototoxicity in live-cell imaging

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2024.240035 discusses multiplexed stimulated emission depletion nanoscopy for multi-color live-cell long-term imaging.

23 Jul 2024

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

In this interview conducted at Pittcon 2024 in San Diego, we spoke to Richard Crocombe about his journey in the field of spectroscopy, focusing on the development of portable spectrometers and their transformative potential in wearable health and fitness technologies.

From Pittcon 18 Jul 2024

Breakthrough biosensors illuminate opioid dynamics in the brain

New research from a Max Planck Florida Institute for Neuroscience researcher could transform how we understand the way opioids affect the brain.

15 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

TurCaMPb: A novel tool for monitoring mitochondrial calcium dynamics

Mitochondria are crucial for maintaining calcium balance in cells, but their calcium dynamics are challenging to study due to pH changes in the mitochondrial matrix, and the lack of cyan-colored GECIs hinders the monitoring of calcium signals across different organelles and cell types.

14 Jul 2024

Scientists map molecules within human brain for first time

Scientists investigating Alzheimer's disease have determined the structure of molecules within a human brain for the very first time.

12 Jul 2024

Revolutionary 3D imaging model enhances IVF blastocyst selection

Innovative research, presented today at the ESHRE 40th Annual Meeting in Amsterdam, has introduced a novel 3D imaging model designed to identify features of blastocysts – the early stage of development for an implanted embryo – associated with successful pregnancies.

8 Jul 2024

Machine learning identifies cancer-driving mutations at CTCF binding sites

Researchers developed a machine learning tool, CTCF-INSITE, to identify mutational hotspots at persistent CTCF binding sites across various cancers, highlighting their role in genomic structure disruption and cancer progression.

7 Jul 2024