Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

The molecular underpinnings by which traumatic brain injury increases Alzheimer's disease risk

Findings indicate BAG3 modulation after traumatic brain injury may mitigate tau buildup and cognitive deficits, presenting a target for Alzheimer's prevention.

18 Oct 2024

Innovative brain simulation enhances understanding of neuron formation

A new computer simulation of how our brains develop and grow neurons has been built by scientists from the University of Surrey.

18 Oct 2024

Understanding how the hippocampus discriminates social threat from safety

How do we distinguish threat from safety? It's a question important not just in our daily lives, but for human disorders linked with fear of others, such as social anxiety or post-traumatic stress disorder (PTSD).

15 Oct 2024

Understanding how aging impacts memory and learning

Our brains change as we age, and connections between the different parts of the brain become less efficient.

15 Oct 2024

Semaglutide enhances cognitive abilities and reduces Alzheimer’s pathology in mice and human brain models

Researchers find that Semaglutide improves cognitive function and reduces amyloid and tau pathology in Alzheimer's disease models, while restoring oxytocin levels in both mice and human brain organoids.

14 Oct 2024

Epigenomic dynamics shape human brain development and neuropsychiatric disorder risks

Researchers investigate chromatin conformational and epigenomic reorganization during the development of the prefrontal cortex and hippocampus.

14 Oct 2024

Researchers decode how the brain identifies and responds to odors

Investigating neuronal activity in the brain, this study highlights how olfactory cues are processed, emphasizing the roles of the piriform cortex and amygdala.

10 Oct 2024

New computer simulation offers insights into brain function

A new computer simulation of how our brains develop and grow neurons has been built by scientists from the University of Surrey.

10 Oct 2024

First map of DNA modification in the hippocampus and prefrontal cortex created

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin - DNA and proteins - plays a critical role.

9 Oct 2024

Researchers uncover neuronal mechanisms of human odor perception

We often only realize how important our sense of smell is when it is no longer there: food hardly tastes good, or we no longer react to dangers such as the smell of smoke.

9 Oct 2024

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Study unravels the unique patterns of brain shrinkage in Alzheimer's disease

The way in which brains shrink in those who develop Alzheimer's disease follows no specific or uniform pattern, finds a new study by researchers at UCL and Radboud University in the Netherlands.

4 Oct 2024

Mild COVID-19 disrupts brain connectivity and reduces memory function in adolescents and young adults

Study reveals localized brain changes in adolescents and young adults post-COVID, including reduced hippocampal volume and disrupted connectivity, correlating with impaired working memory. These findings highlight the importance of understanding long-term cognitive effects of mild COVID-19.

3 Oct 2024

Study identifies brain circuit linking psychedelics to reduced anxiety

Psychedelics have been used in indigenous cultures for centuries, with empirical evidence of their mood and perception altering effects.

3 Oct 2024

New pathway linking neuron selectivity to cognitive disorders uncovered

Neuroscientists from Johns Hopkins Medicine say they have determined how a brain cell surface molecule shapes the way certain neurons behave.

3 Oct 2024

New insights into astrocytes offer hope for Alzheimer's treatment

A research team led by Dr. Hoon Ryu from the Korea Institute of Science and Technology (KIST, President Sang-Rok Oh) Brain Disease Research Group, in collaboration with Director Justin C. Lee of the Institute for Basic Science (IBS, President Do-Young Noh) and Professor Junghee Lee from Boston University Chobanian & Avedisian School of Medicine, has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target.

30 Sep 2024