Membrane News and Research

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New imaging method reveals nanodomains inside ALS-linked protein droplets

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

26 Nov 2025

Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

New skin-permeable polymer delivers insulin without needles

Innovative zwitterionic polymer facilitates insulin absorption through the skin, offering a painless alternative to injections for diabetes management.

25 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Calcium-activated switch improves delivery and potency of cancer-fighting drugs

Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don't make it that far.

24 Nov 2025

New signaling molecule drives development of tissue resident memory T cells

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

22 Nov 2025

Study clarifies how spermine can guard against Alzheimer’s and Parkinson’s

Researchers at the Paul Scherrer Institute PSI have clarified how spermine - a small molecule that regulates many processes in the body's cells - can guard against diseases such as Alzheimer's and Parkinson's: it renders certain proteins harmless by acting a bit like cheese on noodles, making them clump together.

21 Nov 2025

Cryo-EM reveals how proteins are protected during synthesis

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

19 Nov 2025

Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

Pertussis, or whooping cough, remains a highly contagious respiratory infection caused by Bordetella pertussis. Despite inclusion of pertussis vaccines in immunization programs since the 1970s, outbreaks have re-emerged globally due to waning immunity and bacterial evolution.

19 Nov 2025

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases.

18 Nov 2025

Trial investigates how quickly human milk responds to common plant based meat swaps

Replacing beef with a plant based beef substitute for six days changed the fatty acid composition of human milk, increasing medium chain saturated fats and lowering key long chain polyunsaturated fats such as arachidonic acid. These biochemical shifts occurred without changes in maternal weight, appetite, glucose patterns or infant milk intake.

18 Nov 2025

New light-based technology arranges cellular messengers with unprecedented precision

In stunning new time-lapse videos, biological nanoparticles scoot and flit across a starry field of glowing dots. Guided by the invisible chemistry of attraction, these microscopic travelers eventually group together to form perfectly round, glowing circles on a black surface.

18 Nov 2025

Advances in diagnosis and management of chronic subdural hematoma

Chronic subdural hematoma (CSDH) is one of the most common neurosurgical conditions, particularly among the elderly, with an annual incidence ranging from 1.7 to 20.6 per 100,000 people.

18 Nov 2025

Groundbreaking mouse cortex model opens new frontiers in neuroscience

Harnessing the muscle of one of the world's fastest supercomputers, researchers have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever.

17 Nov 2025

New technique revolutionizes the design of drugs that target ion channels

An international team involving the Institute of Chemical Research, a joint centre of the University of Seville and the Spanish National Research Council, has developed a new technique that will accelerate the design of drugs that target ion channels, a type of cell membrane protein involved in numerous diseases, ranging from psychiatric disorders to various types of cancer.

14 Nov 2025

Tiny antibiotic traces found to greatly accelerate resistance spread

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

13 Nov 2025

Cesarean births do not raise infant allergy risk in major Japanese cohort study

In a large Japanese birth cohort, cesarean delivery was not linked to higher risks of eczema, wheezing, atopic dermatitis, or asthma in infants at one year of age. Emergency cesarean delivery was even associated with a modest reduction in eczema, suggesting that mode of birth alone may not drive early-life allergic disease.

13 Nov 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025

Breakthrough ultrasound sensor opens new possibilities for wearable medical devices

Conventional wearable ultrasound sensors have been limited by low power output and poor structural stability, making them unsuitable for high-resolution imaging or therapeutic applications.

12 Nov 2025

Membrane News and Research

New imaging method reveals nanodomains inside ALS-linked protein droplets

Obesity-related metabolic stress may affect brain health far earlier than expected

New skin-permeable polymer delivers insulin without needles

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Calcium-activated switch improves delivery and potency of cancer-fighting drugs

New signaling molecule drives development of tissue resident memory T cells

Study clarifies how spermine can guard against Alzheimer’s and Parkinson’s

Cryo-EM reveals how proteins are protected during synthesis

Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Trial investigates how quickly human milk responds to common plant based meat swaps

New light-based technology arranges cellular messengers with unprecedented precision

Advances in diagnosis and management of chronic subdural hematoma

Groundbreaking mouse cortex model opens new frontiers in neuroscience

New technique revolutionizes the design of drugs that target ion channels

Tiny antibiotic traces found to greatly accelerate resistance spread

Cesarean births do not raise infant allergy risk in major Japanese cohort study

Innovative research reveals FGD3 as a key player in breast cancer cell death

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Breakthrough ultrasound sensor opens new possibilities for wearable medical devices

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