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How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

Researchers examined how imprinted SARS-CoV-2 humoral immunity drives convergent evolution in continuously emerging Omicron subvariants.

2 Nov 2022

Gut microbiota influences social behavior by stimulating microglial remodeling of brain circuits

To learn to socialize, zebrafish need to trust their gut. Gut microbes encourage specialized cells to prune back extra connections in brain circuits that control social behavior, new UO research in zebrafish shows.

1 Nov 2022

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Approximately one-fourth of the general population worldwide has nonalcoholic fatty liver disease, known as NAFLD, an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. NAFLD can lead to cirrhosis, liver cancer and liver failure.

1 Nov 2022

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.

1 Nov 2022

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases. Fortunately, HPV-positive oropharynx cancers have an improved survival rate compared to other head and neck cancers, allowing for less intensive treatment options, especially if diagnosed at early stages.

1 Nov 2022

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

The Breast Cancer Research Foundation (BCRF) has renewed its funding to Elisa Port, MD, and Hanna Irie, MD, PhD, to study new therapeutic approaches that target aggressive triple-negative breast cancer.

31 Oct 2022

IHV researchers receive $7.5 million to control cancer among people living with HIV in sub-Saharan Africa

Institute of Human Virology researchers at the University of Maryland School of Medicine (UMSOM) have received two five-year awards from the National Institutes of Health's National Cancer Institute (NCI) for a total of $7.5 million.

31 Oct 2022

Researchers use AI to predict compounds that could neutralize baldness

Hair loss is undesirable for many men - and women - because one's hairstyle is often closely tied to their self-confidence.

31 Oct 2022

Increasing Awareness Surrounding Ataxia

In this interview, we speak to Dr. Lauren Moore from the National Ataxia Foundation about the condition and the importance of raising awareness for ataxia.

31 Oct 2022

Ubiquigent obtains exclusive license for UbiSite technology to strengthen its specialist drug discovery services

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitylase (DUB) modulators as new therapeutics for areas of high unmet medical need, has signed an exclusive license with the University of Southern Denmark for its UbiSite® technology.

31 Oct 2022

New insights on antibody response against SARS-CoV-2 Omiron sublineages

Knowing how well vaccination against one SARS-CoV-2 strain (with or without previous infection) counteracts infection with a different strain is a critical research question.

28 Oct 2022

Study provides new insights into genetic form of frontotemporal dementia

Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide.

28 Oct 2022

Newly developed chemical compounds show promise as potential anticancer therapy

A University of Kentucky Markey Cancer Center researcher's team developed new chemical compounds that show promise as a potential anticancer therapy to treat aggressive tumors.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Using stem cell cloning to identify the origin of lethal stomach and esophageal cancers

The University of Houston is leading a team of cancer researchers and experts in stem cell cloning to identify the origin of two very lethal cancers of the stomach and esophagus - esophageal adenocarcinoma (EAC) and intestinal gastric cancer (iGC).

27 Oct 2022

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy.

27 Oct 2022

AKT inhibitor shows promise in a trial matching new treatments to cancer patients based on genetic make-up of tumors

In a trial matching new treatments to cancer patients based on the genetic make-up of their tumors, 22% of the patients treated with the AKT inhibitor drug ipatasertib had their tumors shrink.

27 Oct 2022

Advanced type of nanoparticle could help fight hard-to-treat cancers

Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers.

27 Oct 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

Study provides a guide to neutralizing Lassa virus using a trio of rare antibodies

A new study from scientists at La Jolla Institute for Immunology (LJI) gives researchers a guide to neutralizing Lassa virus using a trio of rare antibodies isolated from survivors of Lassa virus infection.

26 Oct 2022

Therapeutics News and Research

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

Gut microbiota influences social behavior by stimulating microglial remodeling of brain circuits

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

IHV researchers receive $7.5 million to control cancer among people living with HIV in sub-Saharan Africa

Researchers use AI to predict compounds that could neutralize baldness

Increasing Awareness Surrounding Ataxia

Ubiquigent obtains exclusive license for UbiSite technology to strengthen its specialist drug discovery services

New insights on antibody response against SARS-CoV-2 Omiron sublineages

Study provides new insights into genetic form of frontotemporal dementia

Newly developed chemical compounds show promise as potential anticancer therapy

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Using stem cell cloning to identify the origin of lethal stomach and esophageal cancers

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

AKT inhibitor shows promise in a trial matching new treatments to cancer patients based on genetic make-up of tumors

Advanced type of nanoparticle could help fight hard-to-treat cancers

New studies point to a broadly applicable treatment for neurodegenerative diseases

Study provides a guide to neutralizing Lassa virus using a trio of rare antibodies

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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