Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Using electric current to directly control gene expression

A team of researchers led by ETH professor Martin Fussenegger has succeeded in using an electric current to directly control gene expression for the first time.

28 May 2020

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

A recent paper by researchers from China demonstrated comparable expression levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry mediators in adults and children, suggesting that previously implied difference in viral-entry associated genes is likely not responsible for milder symptoms in children. The study is currently available on the medRxiv preprint server.

27 May 2020

Collagen maturation regulates PEDF availability, study shows

Cells are like tiny self-contained machines that are constantly fine-tuned in response to both internal and external signals. Some of these signals are induced by extracellular ligands, specialized proteins that bind to specific receptors on the cell surface, stimulating signaling pathways and altering gene expression.

26 May 2020

Minuscule tracking devices give unprecedented peek into how cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

26 May 2020

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

A new federal grant will allow young scientists to delve into the mechanisms of emotional eating and preeclampsia and other disorders not considered "classic" metabolic diseases.

26 May 2020

New study reveals complex role of immune-system molecule in Huntington's disease

More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of promoting the eventual neurological devastation associated with the genetic condition.

26 May 2020

3D model displays arrangement of intrinsic neurons in the rat heart

An interdisciplinary team of researchers has developed a virtual 3D heart, digitally showcasing the heart's unique network of neurons for the first time.

26 May 2020

Rejuvenated fibroblasts could be used in regenerative medicine, stem cell engineering

Fibroblasts are the most common connective tissue cells. They produce the structural framework for animal tissues, synthesize the extracellular matrix and collagen, and play a critical role in wound healing.

26 May 2020

Researchers identify genetic mechanisms that produce radioresistance in cancer cells

Cancer stem cells are a cell type that was previously little known. They are resistant to irradiation and prevent the effective treatment of many types of cancer. A research group from Innsbruck has now identified two genetic mechanisms that produce this radioresistance.

26 May 2020

The infection of lung stem cells may determine SARS-CoV-2 pathogenicity

A group of researchers from Russia and France has demonstrated how stem cells in the lungs can be readily infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to significant defects in their regeneration capacity and more severe coronavirus disease (COVID-19). Their manuscript is currently available on the preprint server bioRxiv.

25 May 2020

Genetic discoveries show promise for developing new treatment targets for schizophrenia

In recent years, genome-wide association studies (GWAS) have identified many different genetic variants associated with schizophrenia.

22 May 2020

Bariatric surgery may alter gene expression in fat tissue

Altered gene expression in fat tissue may help explain why individuals who have regained weight after weight loss surgery still experience benefits such as metabolic improvements and a reduced risk of type 2 diabetes.

21 May 2020

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unlikely to infect human placenta through the canonical cell entry mediators, Wayne State University researchers showed that other interacting proteins may still play an important role during the viral infection. The study is currently available on the preprint server bioRxiv.

20 May 2020

Henry Ford Health System first to enroll a pediatric patient in HEROS study

Henry Ford Health System is first in the country to enroll a patient in the Human Epidemiology and Response to SARS-CoV-2 study, which aims to help determine the rate of SARS-CoV-2, the virus that causes COVID-19, among U.S. children and their family members, and what percentage of children infected with SARS-CoV-2 develop symptoms of the disease.

20 May 2020

Certain corticosteroid could improve severe COVID-19, say researchers

Researchers at Wayne State University and Henry Ford Health System in Michigan have conducted a study indicating that the corticosteroid methylprednisolone could improve outcomes among patients with severe coronavirus disease 2019 (COVID-19).

20 May 2020

Study shows how normal RAS interacts with mutated RAS in living cells

Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS.

19 May 2020

A new treatment option for activating cellular defenses against neurodegenerative disease

Talk about motherly instincts: Biologists at the University of Iowa have learned that female roundworms can alert their future offspring of dangers they will encounter when born, and the mothers pass on these warnings even before the offspring have been conceived.

19 May 2020

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious over the course of multiple studies of several different types of cancers.

18 May 2020

Smoking increases ACE2 protein in the lungs which may promote COVID-19 infection

Previous data from COVID-19 patients suggests that cigarette smokers are more likely to have health complications.

18 May 2020

Potential new treatment approach to fatal COVID-19

Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19).

18 May 2020

Gene Expression News and Research

Further Reading

Using electric current to directly control gene expression

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

Collagen maturation regulates PEDF availability, study shows

Minuscule tracking devices give unprecedented peek into how cells change with time

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

New study reveals complex role of immune-system molecule in Huntington's disease

3D model displays arrangement of intrinsic neurons in the rat heart

Rejuvenated fibroblasts could be used in regenerative medicine, stem cell engineering

Researchers identify genetic mechanisms that produce radioresistance in cancer cells

The infection of lung stem cells may determine SARS-CoV-2 pathogenicity

Genetic discoveries show promise for developing new treatment targets for schizophrenia

Bariatric surgery may alter gene expression in fat tissue

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Henry Ford Health System first to enroll a pediatric patient in HEROS study

Certain corticosteroid could improve severe COVID-19, say researchers

Study shows how normal RAS interacts with mutated RAS in living cells

A new treatment option for activating cellular defenses against neurodegenerative disease

Study shows how cancer protein changes may accelerate tumorigenesis and metastasis

Smoking increases ACE2 protein in the lungs which may promote COVID-19 infection

Potential new treatment approach to fatal COVID-19

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