Therapeutics News and Research

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New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upwards of a billion dollars.

18 Oct 2022

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

17 Oct 2022

Researchers explore the development of mRNA vaccines against respiratory syncytial virus

Recently, researchers discussed the development of messenger ribonucleic acid (mRNA) vaccines against the respiratory syncytial virus (RSV).

17 Oct 2022

How the ‘love hormone’ oxytocin may have heart-healing properties

In this interview, News Medical speaks to Dr. Aitor Aguirre, Assistant Professor of Biomedical Engineering at Michigan State University, about how the ‘love hormone’ oxytocin may provide heart-healing properties.

17 Oct 2022

Selective immunoglobulin A deficiency a risk factor for severe COVID-19

In a recent study published in The Journal of Allergy and Clinical Immunology, researchers in New Zealand gathered evidence to show that selective immunoglobulin A deficiency (sIgAD) is an understated risk factor for severe coronavirus disease 2019 (COVID-19).

17 Oct 2022

Inhalation therapeutics against COVID-19

A recent study published in the Pulmonary Pharmacology & Therapeutics journal described different inhalation therapeutic agents for treating respiratory viral infections like coronavirus disease 2019 (COVID-19).

17 Oct 2022

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

In silico studies assess the binding efficacy of phytoconstituents against active sites of SARS-CoV-2.

16 Oct 2022

Study illuminates how pain neurons protect the gut from damage

Pain has been long recognized as one of evolution's most reliable tools to detect the presence of harm and signal that something is wrong - an alert system that tells us to pause and pay attention to our bodies.

14 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes - or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

Largest academic collaboration aims to transform the treatment for pediatric cancers

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children's Research Hospital today announced the largest academic collaboration of its kind to transform and accelerate the identification of vulnerabilities in pediatric cancers and translate them into better treatments.

13 Oct 2022

Potent antibiotic-loaded bone-cement could be used to treat bone infections

Each year, 700,000 people die due to antibiotic resistance. A growing global population unfortunately generates a growing resistance to established antibiotic treatments - a threat that has been met with insufficient funding and dwindling inspiration, as commercial incentives for developing new antibiotics have fallen.

13 Oct 2022

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways.

13 Oct 2022

Bionic pancreas effective at maintaining blood glucose levels in people with type 1 diabetes

A device known as a bionic pancreas, which uses next-generation technology to automatically deliver insulin, was more effective at maintaining blood glucose (sugar) levels within normal range than standard-of-care management among people with type 1 diabetes, a new multicenter clinical trial has found.

12 Oct 2022

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

A clinical trial to evaluate the antiviral drug tecovirimat, also known as TPOXX, in adults and children with monkeypox has begun in the Democratic Republic of the Congo (DRC).

12 Oct 2022

Molnupiravir and nirmatrelvir-ritonavir treatments are effective in reducing mortality among high-risk COVID-19 patients

A recent study determines the relationship between molnupiravir and nirmatrelvir-ritonavir and all-cause mortality.

12 Oct 2022

Clinical trial to test the safety, efficacy of bacteriophages for treating P. aeruginosa infections in CF patients

Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs and other organs in the body.

11 Oct 2022

Exploring the possibilities of plasma-based therapies for cancer

Exploring the possibilities of atmospheric-pressure plasmas to develop and consolidate new medical therapies is the main objective of the PlasTHER network, an initiative funded by the European Union under the COST Actions.

11 Oct 2022

"Smart surveillance" for viral spillover needed to lessen the consequences of next pandemic

"Smart surveillance" for viral spillover from animals to humans, targeted preparedness and drug and vaccine research, and worldwide cooperation on surveillance and stopping disease spread are required to reduce deaths and lessen the economic consequences of the next pandemic, according to an international team of scientists.

10 Oct 2022

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Researchers have identified a promising strategy for development of broad-spectrum antiviral therapies that centers around promoting a strong immune response capable of stopping a number of viruses in their infectious tracks.

10 Oct 2022

Independent Task Force report outlines a One Health approach to address risk factors for future pandemics

The Independent Task Force on COVID-19 and other Pandemics (www.independentcovidtaskforce.org) announced that their report "Pandemic Origins and a One Health Approach to Preparedness and Prevention: Solutions Based on SARS-CoV-2 and Other RNA Viruses" has been published in the Proceedings of the National Academy of Sciences.

10 Oct 2022

Therapeutics News and Research

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

Researchers explore the development of mRNA vaccines against respiratory syncytial virus

How the ‘love hormone’ oxytocin may have heart-healing properties

Selective immunoglobulin A deficiency a risk factor for severe COVID-19

Inhalation therapeutics against COVID-19

In silico studies identify potent plant metabolites capable of inhibiting SARS-CoV-2

Study illuminates how pain neurons protect the gut from damage

Metabolite discovery offers a potential way to address metabolic conditions

Largest academic collaboration aims to transform the treatment for pediatric cancers

Potent antibiotic-loaded bone-cement could be used to treat bone infections

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

Bionic pancreas effective at maintaining blood glucose levels in people with type 1 diabetes

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

Molnupiravir and nirmatrelvir-ritonavir treatments are effective in reducing mortality among high-risk COVID-19 patients

Clinical trial to test the safety, efficacy of bacteriophages for treating P. aeruginosa infections in CF patients

Exploring the possibilities of plasma-based therapies for cancer

"Smart surveillance" for viral spillover needed to lessen the consequences of next pandemic

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Independent Task Force report outlines a One Health approach to address risk factors for future pandemics

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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