Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study: Highly efficient and balanced immune response key to avoiding COVID-19 symptoms

By analyzing blood samples from individuals infected with SARS-CoV-2, researchers in Singapore have begun to unpack the different responses by the body's T cells that determine whether or not an individual develops COVID-19.

1 Mar 2021

Cellular maps capture COVID-19 pathogenesis in detail

Researchers in the United States and Finland have used tissues from people who died from coronavirus disease 2019 (COVID-19) to generate detailed cellular maps of the pathogenetic processes that occur within affected organs during severe disease.

1 Mar 2021

Combination of deep brain stimulation and exercise has potential benefits for treating ataxia

New research from Baylor College of Medicine scientists shows that a combination of deep brain stimulation (DBS) and exercise has potential benefits for treating ataxia, a rare genetic neurodegenerative disease characterized by progressive irreversible problems with movement.

27 Feb 2021

Biomarkers in the blood can predict severe outcomes in COVID-19 patients

When patients with COVID-19 arrive in emergency rooms, there are relatively few ways for doctors to predict which ones are more likely to become critically ill and require intensive care and which ones are more likely to enjoy a quick recovery.

26 Feb 2021

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Researchers have developed a stable and ultrapotent homotrimeric Pittsburgh inhalable Nanobody 21 (PiN-21) against SARS-CoV-2 infection in Syrian hamsters. They demonstrated the high therapeutic efficacy of this homotrimeric Nb, leveraging both intranasal and aerosol delivery.

26 Feb 2021

Study explains the evolution of SARS-CoV-2 virus

As COVID-19 sweeps the world, related viruses quietly circulate among wild animals. A new study shows how SARS-CoV-2, the virus that causes COVID-19, and SARS-CoV-1, which caused the 2003 SARS outbreak, are related to each other.

26 Feb 2021

New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates

Frontline staff at Norfolk and Norwich University Hospitals are among the first in the country to benefit from the rollout of more accurate saliva tests in a bid to curb Covid transmission rates.

25 Feb 2021

Researchers probe deeper into the neuronal mechanisms underlying olfactory dysfunction in Alzheimer’s

Loss of smell or olfactory dysfunction is an early indication of the neurodegenerative Alzheimer's disease (AD) and appears in approximately 90% of all patients.

25 Feb 2021

UC San Diego receives $33 million from NIH for five COVID-19 diagnostic projects

University of California San Diego was awarded five Rapid Acceleration of Diagnostics (RADx) projects by the National Institutes of Health, totaling nearly $33 million over four years.

25 Feb 2021

Study identifies how military blast exposures affect the brain, increase risk of Alzheimer's

Research shows that Soldiers exposed to shockwaves from military explosives are at a higher risk for developing Alzheimer's disease -- even those that don't have traumatic brain injuries from those blasts.

25 Feb 2021

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children

A study aiming to develop a new therapeutic technique could bring a revolution in our approach to treating rare, fatal Sanfilippo syndrome, a disorder that affects children as young as 2 years old and leads to childhood dementia and premature death.

24 Feb 2021

Study offers new insights into "Niemann-Pick type C disease"

In the journal Nature Communications, scientists of the German Center for Neurodegenerative Diseases (DZNE) report new findings on the mechanisms of "Niemann-Pick type C disease" (NPC).

24 Feb 2021

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

A team of researchers examined PT150, which is an allosteric modulator of androgen and glucocorticoid receptors, to assess whether it had any antiviral activity or immunomodulatory activity to decrease the hyperinflammatory response of SARS-CoV-2 infection.

24 Feb 2021

Study: Abundance of iron can drive cancer cell death in neuroblastoma

Neuroblastoma is a cancer that develops in nerve tissue, most commonly in the glands around the kidneys. The gene MYCN is overexpressed in 20-25% of neuroblastoma, and MYCN-amplified neuroblastoma contributes to a considerable percentage of pediatric cancer-related deaths.

24 Feb 2021

AMP survey results indicate significant decline in molecular diagnostic testing

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today released the preliminary results of its "Molecular Testing for Cancer during COVID-19" survey of clinical laboratories.

23 Feb 2021

Innate immune system overreacts in patients with severe COVID-19

In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients.

23 Feb 2021

Study identifies potential therapeutic target for treatment of Huntington's disease

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations.

23 Feb 2021

Scientists identify new compound that reverses ALS neuron damage

Northwestern University scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims.

23 Feb 2021

Propranolol can be used to treat cerebral cavernous malformations

Propranolol, a drug that is efficacious against infantile haemangiomas ("strawberry naevi", resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterized by misshapen blood vessels in the brain and elsewhere.

23 Feb 2021

Protective COVID-19 antibodies can transfer from mothers to babies in the womb

Antibodies that guard against COVID-19 can transfer from mothers to babies while in the womb, according to a new study from Weill Cornell Medicine and NewYork-Presbyterian researchers published in the American Journal of Obstetrics and Gynecology.

23 Feb 2021

Pathology News and Research

Further Reading

Study: Highly efficient and balanced immune response key to avoiding COVID-19 symptoms

Cellular maps capture COVID-19 pathogenesis in detail

Combination of deep brain stimulation and exercise has potential benefits for treating ataxia

Biomarkers in the blood can predict severe outcomes in COVID-19 patients

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Study explains the evolution of SARS-CoV-2 virus

New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates

Researchers probe deeper into the neuronal mechanisms underlying olfactory dysfunction in Alzheimer’s

UC San Diego receives $33 million from NIH for five COVID-19 diagnostic projects

Study identifies how military blast exposures affect the brain, increase risk of Alzheimer's

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children

Study offers new insights into "Niemann-Pick type C disease"

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

Study: Abundance of iron can drive cancer cell death in neuroblastoma

AMP survey results indicate significant decline in molecular diagnostic testing

Innate immune system overreacts in patients with severe COVID-19

Study identifies potential therapeutic target for treatment of Huntington's disease

Scientists identify new compound that reverses ALS neuron damage

Propranolol can be used to treat cerebral cavernous malformations

Protective COVID-19 antibodies can transfer from mothers to babies in the womb

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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