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Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

A new study from Karolinska Institutet in Sweden shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. The study is published today in the journal Nature Communications.

23 Feb 2022

Cell stress-related biochemical events may be partly driving Parkinson's disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

Scientists from Israel have recently estimated the levels of circulating microRNAs (miRNAs) in hospitalized coronavirus disease 2019 (COVID-19) patients with the aim of identifying prognostic biomarkers for disease severity. They have identified miR-155, an important regulatory molecule in the immune system, as a potential biomarker to predict COVID-19 severity and mortality.

22 Feb 2022

CD91 receptor promotes SARS-CoV-2 infection

researchers find that LRP1/CD91 is a leading molecule in virus-host cell interactions that causes infection by many RNA viruses.

22 Feb 2022

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

Every kind of T cell has a job to do. A healthy immune system makes sure no T cell oversteps.

22 Feb 2022

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease.

22 Feb 2022

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

In a recent study published in the journal PLoS ONE, researchers investigated the effect of genetic variability based on accessory gene deletions on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and the clinical severity of coronavirus disease 2019 (COVID-19).

22 Feb 2022

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

21 Feb 2022

Researchers unravel essential final steps in the production of mRNA

Proteins need to interact in a complex manner for a so-called "messenger RNA" (mRNA) to be created in human cells from a precursor molecule. mRNA provides a blueprint for proteins; the first vaccines against the coronavirus are also based on mRNAs.

21 Feb 2022

Study suggests non-classical inhibition of TBK1/IKKε is protective against severe COVID-19 immunopathology in vivo

A study posted suggested the inhibition of TBK1 and its homolog KKε could decrease the severity of COVID-19.

21 Feb 2022

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

A new study describes a potential new approach to treating COVID-19 in the form of single-chain fragment variable (scFv) antibodies.

20 Feb 2022

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

A new study explains how SARS-CoV-2 adapts its immunogenicity to the immune response of the host.

20 Feb 2022

Structure of protein that can pump toxic molecules out of bacterial cells revealed

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple antibiotics.

18 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Researchers investigated the role of platelets in the adverse immune response against a COVID-19 vaccine.

16 Feb 2022

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Acne on the face is often treated with topical antibiotics, which tend to be used for an extended period of time and contribute to the serious problem of antibiotic resistance.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

Surprising discovery about genetic form of microcephaly has potential to inform treatment strategies

Virginia Tech researchers publishing in the Journal of Medical Genetics made a discovery about a genetic form of microcephaly -- a condition where babies' heads and brains are smaller and grow more slowly than those of unaffected children.

14 Feb 2022

Molecule News and Research

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Study shows how certain RNA molecules control the repair of damaged DNA in cancer cells

Cell stress-related biochemical events may be partly driving Parkinson's disease

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Circulating miR-155 may predict chances of survival in hospitalized COVID-19 patients

CD91 receptor promotes SARS-CoV-2 infection

Specialized subset of CD4+ T cells jump into action early during an infection, study shows

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers unravel essential final steps in the production of mRNA

Study suggests non-classical inhibition of TBK1/IKKε is protective against severe COVID-19 immunopathology in vivo

Inhalable antibody fragments offer broad protection from SARS-CoV-2 variants

Mechanism of fatty-acid coupled adaptive immunity in SARS-CoV-2 revealed

Structure of protein that can pump toxic molecules out of bacterial cells revealed

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

Surprising discovery about genetic form of microcephaly has potential to inform treatment strategies

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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