Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

STING activation may be a new approach to reduce graft-versus-host disease

MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

11 Feb 2021

Hamamatsu's Market Report: At The Tipping Point - What Is The Future of Digital Pathology?

Hamamatsu's "At the tipping point" market report provides an insight into the current state of digital pathology and the impact of COVID-19 in this industry. Hamamatsu commissioned Sage Growth Partners to conduct an in-depth quantitative and qualitative survey to discover elements that influence and hinder adoption and to compile this report.

From Hamamatsu Photonics Europe 11 Feb 2021

Study: Neuron structures are dissimilar between the brain areas in every individual

It was reported that the volume of the brain areas such as the superior temporal gyrus and anterior cingulate cortex reduces in schizophrenia but a precise change of three-dimensional structure of neuron has remained unclear.

11 Feb 2021

Exposure to seasonal coronaviruses does not produce antibodies that protect against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2021

Metal-containing radiopharmaceuticals could improve access to diagnostic imaging of AD

A team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State University and D. Mendeleev University of Chemical Technology of Russia has summarized metal-containing diagnostic agents for positron emission tomography (PET), magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT) imaging of Alzheimer's disease (AD).

9 Feb 2021

New combination treatment approach improves overall survival in mice with glioblastoma

In a study of mice, researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new approach that combines an anti-psychotic drug, a statin used to lower high cholesterol levels, and radiation to improve the overall survival in mice with glioblastoma.

9 Feb 2021

Study finds way to detect ovarian cancer in patients using Pap test samples

A study led by researchers at the University of Minnesota Medical School found a way to detect the presence of ovarian cancer in patients using Pap test samples, normally used to detect cervical cancer.

9 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Researchers gain insight into the biological processes of chytrid fungus

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

8 Feb 2021

After nearly 60 years of marriage, this Missouri couple stayed together to the end

Arthur Kelley could barely raise his voice above a whisper last fall when he told a nursing assistant he never wanted his wife, Maggie, to be alone. After almost 60 years of marriage, five children and a lifetime filled with more victories than defeat, Kelley wanted to be there for his ailing wife, even if she didn't know he was there.

8 Feb 2021

In vitro human blood-brain barrier model found to have a critical flaw

Cells used to study the human blood brain barrier in the lab aren't what they seem, throwing nearly a decade's worth of research into question, a new study from scientists at Columbia University Vagelos College of Physicians and Surgeons and Weill Cornell Medicine suggests.

8 Feb 2021

Gene panel test enables highly accurate diagnosis of liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

5 Feb 2021

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

Researchers at Yerkes National Primate Research Center, Emory University, have developed a COVID-19 vaccine that has proven safe and effective in mice and monkeys.

4 Feb 2021

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Aging-US published "Sulforaphane promotes C. elegans longevity and healthspan via DAF- 16/DAF-2 insulin/IGF-1 signaling" which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its effect on healthspan and longevity are unclear.

4 Feb 2021

Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal RNAs

Hypoxia -- where a tissue is deprived of an adequate supply of oxygen -- is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Study of how cells adapt to this critical stressor, by altering their metabolism to survive in a low-oxygen environment, is important to better understand tumor growth and spread.

4 Feb 2021

Viral-caused cancer in California sea lions has major health implications for humans

20-plus years of data in a newly released study by The Marine Mammal Center shows ocean pollutants is one of the leading causes of cancer in sea lions and highlights how exposure to environmental contaminants can fast-track the likelihood of humans developing virally caused cancers.

3 Feb 2021

New technology uses near-infrared imaging and machine learning to find hidden tumors

Tumors can be damaging to surrounding blood vessels and tissues even if they're benign. If they're malignant, they're aggressive and sneaky, and often irrevocably damaging. In the latter case, early detection is key to treatment and recovery.

3 Feb 2021

Remyelinating drug shows potential to improve vision in patients with MS

A team led by a biomedical scientist at the University of California, Riverside, reports a drug -- an estrogen receptor ligand called indazole chloride (IndCl) -- has the potential to improve vision in patients with multiple sclerosis, or MS.

2 Feb 2021

Immune profiling shows differences in COVID-19 and influenza pathologic pathways

A study conducted at Johns Hopkins University School of Medicine in Baltimore has revealed distinct differences in the immune pathways that are activated by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and those that are activated by influenza.

2 Feb 2021

Automated method identifies and tracks harmful tau deposits involved in Alzheimer's disease

Amyloid-beta and tau are the two key abnormal protein deposits that accumulate in the brain during the development of Alzheimer's disease, and detecting their buildup at an early stage may allow clinicians to intervene before the condition has a chance to take hold.

2 Feb 2021

Pathology News and Research

Further Reading

STING activation may be a new approach to reduce graft-versus-host disease

Hamamatsu's Market Report: At The Tipping Point - What Is The Future of Digital Pathology?

Study: Neuron structures are dissimilar between the brain areas in every individual

Exposure to seasonal coronaviruses does not produce antibodies that protect against SARS-CoV-2

Metal-containing radiopharmaceuticals could improve access to diagnostic imaging of AD

New combination treatment approach improves overall survival in mice with glioblastoma

Study finds way to detect ovarian cancer in patients using Pap test samples

Study implicates disruption in prenatal neurogenesis in the development of ASDs

Researchers gain insight into the biological processes of chytrid fungus

After nearly 60 years of marriage, this Missouri couple stayed together to the end

In vitro human blood-brain barrier model found to have a critical flaw

Gene panel test enables highly accurate diagnosis of liposarcomas

Emory MVA COVID-19 vaccine proven safe and effective in mice and monkeys

Sulforaphane prolongs lifespan and healthspan of C. elegans through insulin/IGF-1 signaling

Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal RNAs

Viral-caused cancer in California sea lions has major health implications for humans

New technology uses near-infrared imaging and machine learning to find hidden tumors

Remyelinating drug shows potential to improve vision in patients with MS

Immune profiling shows differences in COVID-19 and influenza pathologic pathways

Automated method identifies and tracks harmful tau deposits involved in Alzheimer's disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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