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Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

Nosopharm, a company dedicated to the research and development of new anti-infective drugs, and the University of Illinois at Chicago today announce the publication of a study in Molecular Cell on the mechanism of action of odilorhabdins, a new class of antibiotics to combat antibiotic resistance.

9 Apr 2018

Research team identifies new class of antibiotics to fight drug resistance

Researchers from the University of Illinois at Chicago and Nosopharm, a biotechnology company based in Lyon, France, are part of an international team reporting on the discovery of a new class of antibiotics.

6 Apr 2018

New discovery may offer insight into treating sickle cell anemia and other blood disorders

Discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia.

4 Apr 2018

DNA-mimicking synthetic molecule could lead to new HIV treatment

Researchers have developed a synthetic compound that mimics the surface of DNA and is able to inhibit several DNA-processing enzymes.

4 Apr 2018

UD researcher investigates role of new compound in fighting age-related diseases

A University of Delaware researcher is investigating a novel compound's role in combating age-related chronic diseases like mild cognitive disorder and dementia.

3 Apr 2018

BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Arthritis flares - the unpredictable and often sudden worsening of arthritis symptoms -- can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians.

3 Apr 2018

Stable proteins in the brain offer clues to long-term memory and learning in mice

In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory.

3 Apr 2018

Researchers create new compound that appears to activate cancer-fighting T cells

Invariant natural killer T (iNKT) cells are powerful weapons our body's immune systems count on to fight infection and combat diseases like cancer, multiple sclerosis, and lupus. Finding ways to spark these potent cells into action could lead to more effective cancer treatments and vaccines.

2 Apr 2018

Natural dietary supplement tends to improve blood pressure and arterial health

Scientists have long known that restricting calories can fend off physiological signs of aging, with studies in fruit flies, roundworms, rodents and even people showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan.

29 Mar 2018

Macrophages stimulated to produce potent anti-inflammatory molecule

Researchers have discovered that macrophages, which play a key role in inflammation, also produce an anti-inflammatory molecule called itaconate.

29 Mar 2018

Research pinpoints potential weak link in bacterial wall-building protein

The wall that surrounds bacteria to shield them from external assaults has long been a tantalizing target for drug therapies. Indeed, some of modern medicine's most reliable antibiotics disarm harmful bacteria by disrupting the proteins that build their protective armor.

28 Mar 2018

UTA researchers take advantage of biochemistry technique to identify rare radioactive decays

UTA researchers are leading an international team developing a new device that could enable physicists to take the next step toward a greater understanding of the neutrino, a subatomic particle that may offer an answer to the lingering mystery of the universe's matter-antimatter imbalance.

28 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Researchers identify chemical responsible for carcinogen formation in recycled wastewater

Engineers at wastewater recycling plants can rest easy knowing that their methods for minimizing the formation of a potent carcinogen are targeting the right chemical compound.

23 Mar 2018

New study identifies key cellular mechanisms behind vascular aging in mice

We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School.

22 Mar 2018

Researchers find investigational compound to treat triple negative breast cancer after brain metastasis

Researchers at Houston Methodist used computer modeling to find an existing investigational drug compound for leukemia patients to treat triple negative breast cancer once it spreads to the brain.

22 Mar 2018

TPP-related compounds selectively shut down cancer cells with little or no effect on healthy cells

SCIENTISTS seeking to make chemotherapies which are less harmful to cancer patients have reported "highly promising" results from a synthetic molecule called TPP.

21 Mar 2018

Compound found in beet extract could help slow progression of Alzheimer’s disease

A compound in beets that gives the vegetable its distinctive red color could eventually help slow the accumulation of misfolded proteins in the brain, a process that is associated with Alzheimer's disease. Scientists say this discovery could lead to the development of drugs that could alleviate some of the long-term effects of the disease, the world's leading cause of dementia.

20 Mar 2018

New diabetes drug may help obese people shed body weight

A compound that mimics a naturally occurring hormone that regulates appetite may help people who have obesity but not diabetes to lose weight, a new study suggests.

19 Mar 2018

Majority of Hispanic patients prefer HIV testing in Spanish, UB research finds

Clinicians are advised to never group Hispanic Americans under one collective identity. But when it comes to HIV testing, the desire to communicate with health care providers in Spanish nearly transcends ethnicity.

14 Mar 2018

Compound News and Research

Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

Research team identifies new class of antibiotics to fight drug resistance

New discovery may offer insight into treating sickle cell anemia and other blood disorders

DNA-mimicking synthetic molecule could lead to new HIV treatment

UD researcher investigates role of new compound in fighting age-related diseases

BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Stable proteins in the brain offer clues to long-term memory and learning in mice

Researchers create new compound that appears to activate cancer-fighting T cells

Natural dietary supplement tends to improve blood pressure and arterial health

Macrophages stimulated to produce potent anti-inflammatory molecule

Research pinpoints potential weak link in bacterial wall-building protein

UTA researchers take advantage of biochemistry technique to identify rare radioactive decays

Antibody sweeps away Alzheimer's plaques in mice

Researchers identify chemical responsible for carcinogen formation in recycled wastewater

New study identifies key cellular mechanisms behind vascular aging in mice

Researchers find investigational compound to treat triple negative breast cancer after brain metastasis

TPP-related compounds selectively shut down cancer cells with little or no effect on healthy cells

Compound found in beet extract could help slow progression of Alzheimer’s disease

New diabetes drug may help obese people shed body weight

Majority of Hispanic patients prefer HIV testing in Spanish, UB research finds

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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