Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

New insights into the mechanisms of efavirenz-induced neurotoxicity

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and neurocognitive impairment in roughly 50 percent of patients. The drug is associated with abnormal lipid levels in blood plasma, but the molecular mechanisms responsible for negative clinical observations are unknown.

18 Sep 2024

Research reveals only a few brain regions remain untouched by transition to motherhood

Research shows pregnancy triggers neuroanatomical changes in the brain, with decreased cortical volume and increased white matter integrity over gestation.

17 Sep 2024

Older brains adapt to recognize music by reconfiguring neural activity

Older adults exhibit changes in brain activity when recognizing musical sequences, indicating compensatory mechanisms that help maintain memory despite aging-related declines.

11 Sep 2024

Brain changes related to Alzheimer's risk may increase financial vulnerability in seniors

Older adults who are more vulnerable to financial scams may have brain changes linked to a higher risk of Alzheimer's disease, according to a first-of-its-kind study led by researchers at the USC Dornsife College of Letters, Arts and Sciences.

6 Sep 2024

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

Researchers reveal how aging and psychiatric disorders converge at the cellular level in the orbitofrontal cortex, identifying key gene expression changes that could lead to new therapies.

4 Sep 2024

New protocol explores the combination of aerobic exercise and cognitive rehabilitation for MS patients

Researchers at Kessler Foundation have published a new clinical protocol examining the combination of aerobic exercise and cognitive rehabilitation to improve learning and memory in individuals with multiple sclerosis (MS) who have mobility disability.

3 Sep 2024

Novel approach reverses age-related cognitive decline

The authors investigate the physiological functions of Terc-53 by creating transgenic mice that overexpress this noncoding RNA. They observe that Terc-53 overexpression affects normal aging in mammals, contributing to cognitive decline and shortened lifespan.

27 Aug 2024

Long COVID symptoms may stem from low cortisol and altered brain immune response

Proteins left behind by COVID-19 long after initial infection can cause cortisol levels in the brain to plummet, inflame the nervous system and prime its immune cells to hyper-react when another stressor arises, according to new animal research by University of Colorado Boulder scientists.

19 Aug 2024

Study: Early brain wiring driven by spontaneous cellular activity

In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog - four legs, fur, a tail, etc. - a young child will eventually be able to identify dogs going forward.

16 Aug 2024

Scientists discover brain's 'future map'

Researchers from the RIKEN Center for Brain Science (CBS) in Japan have discovered a region of the brain that encodes where an animal is planning to be in the near future. Linked to internal maps of spatial locations and past movements, activity in the newly discovered grid cells accurately predicts future locations as an animal travels around its environment. Published in Science on August 15th, 2024, the study helps explain how planned spatial navigation is possible.

16 Aug 2024

Study sheds light on neuronal synchronization and conscious experience

For decades, scientists have focused on how the brain processes information in a hierarchical manner, with different brain areas specialized for different tasks.

12 Aug 2024

Prenatal BPA exposure tied to autism risk in boys

Study reveals that prenatal exposure to BPA disrupts aromatase activity in male brains, potentially leading to autism-like symptoms. Treatment with 10-HDA shows promise in reversing these effects.

11 Aug 2024

New NIH grant supports study on fear of falling in multiple sclerosis

Taylor Takla, a Ph.D. candidate in the translational neuroscience program in Wayne State University's School of Medicine, recently received a two-year, $96,812 F31 grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health to study fear of falling in those with multiple sclerosis (MS).

9 Aug 2024

Hippocampus News and Research

Further Reading

New insights into the mechanisms of efavirenz-induced neurotoxicity

Research reveals only a few brain regions remain untouched by transition to motherhood

Older brains adapt to recognize music by reconfiguring neural activity

Brain changes related to Alzheimer's risk may increase financial vulnerability in seniors

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

New protocol explores the combination of aerobic exercise and cognitive rehabilitation for MS patients

Novel approach reverses age-related cognitive decline

Long COVID symptoms may stem from low cortisol and altered brain immune response

Study: Early brain wiring driven by spontaneous cellular activity

Scientists discover brain's 'future map'

Study sheds light on neuronal synchronization and conscious experience

Prenatal BPA exposure tied to autism risk in boys

New NIH grant supports study on fear of falling in multiple sclerosis

Exosome-encapsulated fluorescent sensors enable advanced brain imaging in Alzheimer's research

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Psilocybin reconfigures brain networks, showing potential for lasting therapeutic effects

Brain activity patterns can foreshadow 24-hour seizure risk

Predicting Alzheimer's decline: New model offers personalized insights for patients

High-intensity interval exercise improves brain function in older adults

Experts identify sex and gender differences in cognitive resistance and resilience to Alzheimer's disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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