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Scientists identify a distinct role of retinoic acid during immune response of the gut

A team of scientists from the Renaissance School of Medicine at Stony Brook University have identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

28 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

20 Mar 2023

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Researchers examine whether the involvement of the ipsilateral or contralateral lymph nodes affected the immune response during sequential vaccination.

16 Mar 2023

Host immune system forms small lesions in the intestines in response to bacterial infection

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

Small change to keyhole surgery for prostate cancer can reduce post-operative complications

Surgeons in Germany have shown a small technical change to keyhole surgery for prostate cancer can more than halve one of the most common post-operative complications – where lymphatic fluid collects in the pelvis.

13 Mar 2023

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

9 Mar 2023

Estimation of incubation period and serial interval of mpox virus infections in the United States

In a recent study, researchers determined the mean incubation period and the serial interval estimates of the mpox virus.

7 Mar 2023

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Researchers examined the vaccination effects and local antigen expression efficiency of a needle-free vaccination technique involving pyro-drive liquid jet injection (PYRO) to deliver the naked messenger ribonucleic acid (mRNA) to the skin.

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

HIV creates reservoirs much earlier than expected, study shows

For the first time in humans, a research team has shown that, as early as the first days of infection, HIV is able to create reservoirs where it will hide and persist during antiretroviral therapy.

28 Feb 2023

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Researchers assessed T-cell tolerance checkpoints observed in atherosclerosis.

27 Feb 2023

Exploring biodistribution of cannabidiol nanoparticles and nanoemulsion after intrathecal administration

Researchers evaluated the biodistribution of cannabidiol (CBD) emulsion and nanoparticles in the central nervous system (CNS).

24 Feb 2023

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

Researchers assessed the impact of a single-dose dendritic cell vaccine candidate on immune responses against SARS-CoV-2.

23 Feb 2023

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Patients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to have more-aggressive tumors and significantly lower overall survival (OS) than those in higher-income neighborhoods, according to research led by Roswell Park Comprehensive Cancer Center.

21 Feb 2023

Lymph Nodes News and Research

Scientists identify a distinct role of retinoic acid during immune response of the gut

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Host immune system forms small lesions in the intestines in response to bacterial infection

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Small change to keyhole surgery for prostate cancer can reduce post-operative complications

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Estimation of incubation period and serial interval of mpox virus infections in the United States

Naked mRNA delivered using needle-free PYRO injection presents a safe and effective potential vaccination method

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

What is the role of B cells in breast cancer pathology?

HIV creates reservoirs much earlier than expected, study shows

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Exploring biodistribution of cannabidiol nanoparticles and nanoemulsion after intrathecal administration

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

Income level impacts tumor recurrence and survival in women with ER-positive breast cancer

Study indicates that macrophages that reside in the lymph nodes contribute to the initial Zika virus spread

Could trained scent-detection dogs be used for chronic wasting disease surveillance?

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

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