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Circadian rest-activity patterns may signal frailty risk in older adults

Brigham researchers found an association between alterations in circadian rest-activity rhythms and risk of frailty incidence in older adults.

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model."

15 Nov 2023

Study reveals mechanisms restricting oncogene-driven skin cancer formation

To form a cancer, cells need to accumulate oncogenic mutations that confer tumor-initiating properties.

15 Nov 2023

Investigating the link between gut inflammation, aging, and Alzheimer's disease

A recent study in discusses how gut inflammation is associated with age and Alzheimer's disease.

15 Nov 2023

Sir Peter Barnes on World COPD Day: Awareness, Advances, and the Road Ahead

In this interview, we delve into the remarkable journey of Professor Sir Peter Barnes, a leading figure in respiratory medicine.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

Anti-inflammatory medication does not reduce frailty risk in adults with atherosclerosis

Frailty is a common condition in older populations that increases the risk of adverse health outcomes and mortality.

14 Nov 2023

Alcohol consumption linked to accelerated biological aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Alcohol consumption and epigenetic age acceleration across human adulthood."

14 Nov 2023

New triage system for pregnant women and new mothers improves patient outcomes

Increased vigilance for high blood pressure and diffuse stomach pain. These are some of the characteristics of emergency care adapted for pregnant women and new mothers.

14 Nov 2023

Bioengineered human heart muscle cells and micro-tissues take flight to space

Mount Sinai's Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA's 29th SpaceX commercial resupply services mission, which launched Thursday, November 9.

14 Nov 2023

New app aims to ease burden on caregivers of dementia patients

With the number of Americans living with dementia expected to more than double to 13.8 million by 2060, two Regenstrief Institute research scientists and Indiana University professors have created an app to ease the burden on caregivers.

14 Nov 2023

Self-perception of health influences physical activity levels in older adults with arthritis

People with arthritis who report more negative feelings about how they are aging tend to get less physical activity and perceive themselves as less healthy, according to a new study by researchers at Hospital for Special Surgery (HSS) and Weill Cornell Medicine.

14 Nov 2023

Cancer stem cells induce macrophage aging, creating conditions for tumor formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

14 Nov 2023

Adult children discuss the trials of caring for their aging parents

I am 39 years old. I had to care for my father, who passed from cancer in 2019; my mother, who passed in November 2021 from cancer; and since my mother's passing, I have inherited the care of my grandmother.

14 Nov 2023

What long-term care looks like around the world

Around the world, wealthy countries are struggling to afford long-term care for rapidly aging populations.

14 Nov 2023

Facing financial ruin as costs soar for elder care

Margaret Newcomb, 69, a retired French teacher, is desperately trying to protect her retirement savings by caring for her 82-year-old husband, who has severe dementia, at home in Seattle.

14 Nov 2023

Study shows environment's pivotal role in healthy aging and disease prevention

Study explores new geroscience tools for studying the impact of environmental factors on aging, aiming to delay age-related diseases and disabilities. It highlights how non-genetic factors, like environmental toxins and socio-economic conditions, significantly influence aging and health outcomes.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Intensive blood pressure control reduces dementia risk in adults with hypertension

An intensive, four-year blood-pressure intervention significantly reduced the risk of developing dementia among adults with high blood pressure compared to people who received usual care, in a study reported as late-breaking science today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023