Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Understanding ‘prodromal’ phase in Parkinson’s may prevent disease from developing

In the past 25 years it has become clear that some symptoms of Parkinson's disease occur decades before the development of motor symptoms and clinical diagnosis, and that monitoring these emerging symptoms may provide important insights into the origin and development of the disease.

6 Feb 2019

NanoView Biosciences launches first product for accurate characterization of exosomes

NanoView Biosciences, Inc. today launched its first product, the ExoView™ platform, to enable the accurate identification and characterization of exosomes. The platform is on display this week at the SLAS2019 International Conference & Exhibition in Washington, DC.

From Society for Laboratory Automation and Screening (SLAS) 5 Feb 2019

Researchers identify blood-based biomarkers of Parkinson's disease

Researchers at University of California San Diego School of Medicine and Arizona State University have received funding from The Michael J. Fox Foundation for Parkinson's Research to launch a multi-year, $1.7-million effort to identify blood-based biomarkers of Parkinson's disease, which could improve care and accelerate new treatments for the neurodegenerative disorder, which affects nearly 1 million Americans, with 60,000 new cases diagnosed annually.

5 Feb 2019

Researchers find 'origin' of cancer spread

The discovery of the cell, which they are calling 'the cell of origin' sheds new light on what fuels cancer growth and how to potentially stop it.

4 Feb 2019

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

During a study spanning nearly a decade, researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center have linked the protein clusterin - for the first time -- to many different facets of cardiometabolic syndrome risk through its actions in the liver.

4 Feb 2019

Insilico to present its latest results in AI for Drug Discovery on CXOTalk Show

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery on a live episode of the influential CXOTalk Show on February 8, 2019 at 1:00 PM Eastern time.

1 Feb 2019

Microbes on the tongue could be used to diagnose pancreatic cancer

Researchers have found that disruption in the microbial composition of the tongue coating could serve as a biomarker for early-stage pancreatic cancer.

31 Jan 2019

Japanese researchers develop highly sensitive method to detect potential cancer biomarker

Exosomes regulate intercellular communication in cancers, and are drawing attention as a potential cancer biomarker. A Japanese research group has developed a highly sensitive method for detecting these exosomes that could potentially contribute to early detection of cancer.

31 Jan 2019

New project will develop biomarker-based system to send personalized advice on dietary, lifestyle habits

The PREVENTOMICS European project will develop, from this November and for 3 years, personalized plans for nutrition and lifestyle habits to improve the health of people, based on individual traits such as physical and behavioral traits, lifestyle, genotype, preferences and physical condition.

29 Jan 2019

RNA-induced gene fusion can occur in mammalian cells, reveals study

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome.

29 Jan 2019

Insilico Medicine to present latest advances in aging biomarker development at Longevity Leaders Conference

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest advances in human aging biomarker development at the Longevity Leaders Conference in London, 4 of February.

25 Jan 2019

PET imaging post-HBOT shows improvement in brain metabolism in Alzheimer’s disease

Dr. Paul Harch, Clinical Professor and Director of Hyperbaric Medicine at LSU Health New Orleans School of Medicine, and Dr. Edward Fogarty, Chairman of Radiology at the University of North Dakota School of Medicine, report the first PET scan-documented case of improvement in brain metabolism in Alzheimer's disease in a patient treated with hyperbaric oxygen therapy.

24 Jan 2019

Researchers identify marker protein that offers both diagnostic and therapeutic function

Of all gastrointestinal cancers, pancreatic cancer is one of the most aggressive. Because of this, it has a very low 5-year survival rate of just 5% and a median survival time below 6 months. Additionally, treatment is difficult, with only surgery shown to provide a cure. However, the vast majority of patients have tumors that cannot be removed surgically or their cancer is too advanced or spread too far to be treatable.

24 Jan 2019

Skin samples hold early signs of prion disease, research suggests

Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected as they destroy brain tissue, causing memory loss, mobility issues, and ultimately death.

23 Jan 2019

Insilico to present latest findings in AI for Drug Discovery at 3rd Annual SABPA FTD Forum

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery at the 3rd Annual SABPA FTD Forum in San Diego, California, 2 of February.

23 Jan 2019

Experimental drug can positively modify key characteristic behavior in FXS patients

Researchers at MIND Institute at UC Davis and Rush University Medical Center have found that mavoglurant, an experimental drug known as a mGluR5 negative modulator, can positively modify a key characteristic behavior in individuals with fragile X syndrome.

22 Jan 2019

Bowel cancer on the rise among younger Australians

Bowel cancer screening often begins after the age of fifty. New statistics reveal that it should start earlier because bowel cancer is on the rise among younger population in Australia. The numbers appear in the latest issue of the journal of Cancer Epidemiology, Biomarkers and Prevention.

22 Jan 2019

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease - even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases in Germany.

21 Jan 2019

Blood test detects brain damage linked to Alzheimer’s years before symptoms develop

Researchers have developed a blood test that can detect signs of brain damage among people who will develop Alzheimer’s years before the onset of memory loss.

21 Jan 2019

ACCC survey finds multiple threats to growth of cancer programs

At a time of unprecedented advances in the science of cancer, growing complexity in cancer treatments, and ongoing health policy fluctuation, the Association of Community Cancer Centers ninth annual Trending Now in Cancer Care survey reveals how cancer programs across the country are being impacted by pressure from turbulence in multiple sectors: payers, government, and industry.

18 Jan 2019

Biomarker News and Research

Further Reading

Understanding ‘prodromal’ phase in Parkinson’s may prevent disease from developing

NanoView Biosciences launches first product for accurate characterization of exosomes

Researchers identify blood-based biomarkers of Parkinson's disease

Researchers find 'origin' of cancer spread

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

Insilico to present its latest results in AI for Drug Discovery on CXOTalk Show

Microbes on the tongue could be used to diagnose pancreatic cancer

Japanese researchers develop highly sensitive method to detect potential cancer biomarker

New project will develop biomarker-based system to send personalized advice on dietary, lifestyle habits

RNA-induced gene fusion can occur in mammalian cells, reveals study

Insilico Medicine to present latest advances in aging biomarker development at Longevity Leaders Conference

PET imaging post-HBOT shows improvement in brain metabolism in Alzheimer’s disease

Researchers identify marker protein that offers both diagnostic and therapeutic function

Skin samples hold early signs of prion disease, research suggests

Insilico to present latest findings in AI for Drug Discovery at 3rd Annual SABPA FTD Forum

Experimental drug can positively modify key characteristic behavior in FXS patients

Bowel cancer on the rise among younger Australians

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

Blood test detects brain damage linked to Alzheimer’s years before symptoms develop

ACCC survey finds multiple threats to growth of cancer programs

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

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