Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

6 Jan 2026

Simple drug treatments could help older brains cope with memory decline and postoperative recovery

Simple pharmaceutical interventions could help older brains cope with memory impairment and recovery after surgery, new studies in mice suggest.

6 Jan 2026

Finger-prick blood test shows promise for detecting Alzheimer’s disease biology

Finger-prick dried blood sampling can accurately measure key Alzheimer’s disease biomarkers, including p-tau217, GFAP, and NfL, showing strong concordance with venous plasma and meaningful associations with CSF pathology. While analytical limitations remain, this minimally invasive approach shows promise as a scalable research and screening tool within biomarker-based diagnostic pathways.

6 Jan 2026

Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest University School of Medicine synthesizes emerging evidence that two isoforms of a critical cellular energy sensor play distinct, and sometimes opposing, roles in Alzheimer's disease.

6 Jan 2026

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

A groundbreaking international study has demonstrated that Alzheimer's disease biomarkers can be accurately detected using simple finger-prick blood samples that can be collected at home and mailed to laboratories without refrigeration or prior processing.

5 Jan 2026

New guidelines aim to standardize diagnosis of canine dementia

An international working group of canine cognition experts has released a set of guidelines for veterinarians to use in diagnosing and monitoring canine cognitive dysfunction syndrome (CCDS), or canine dementia.

5 Jan 2026

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

Researchers explore why Alzheimer's affects men and women differently

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

30 Dec 2025

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

23 Dec 2025

AI analysis maps a century of global aging research

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 25, 2025, titled "A natural language processing–driven map of the aging research landscape."

23 Dec 2025

Neuronal master switch reshapes brain activity during learning

Memories and learning processes are based on changes in the brain's neuronal connections and, as a result, in signal transmission between neurons.

23 Dec 2025

Menopause hormone therapy not linked to dementia risk in women

A major review of prior research has found no evidence that menopause hormone therapy either increases or decreases dementia risk in post-menopausal women, in a new study led by University College London (UCL) researchers.

22 Dec 2025

A senescence-based therapeutic approach for temporal lobe epilepsy

Temporal lobe epilepsy, which results in recurring seizures and cognitive dysfunction, is associated with premature aging of brain cells.

22 Dec 2025

Research highlights a potential therapeutic strategy for vascular dementia

A possible new treatment for impaired brain blood flow and related dementias is on the horizon.

22 Dec 2025

Simple blood test maps hidden Alzheimer’s disease changes

This population-based study used plasma pTau217 to estimate how common Alzheimer’s disease neuropathological changes are across age and cognitive status in a Norwegian community cohort. Prevalence rose steeply with age and was strongly associated with APOE ε4 genotype, education level, and kidney function, with implications for future use of blood biomarkers in clinical practice.

21 Dec 2025

Long-approved drug shows promise in slowing neuron loss in Alzheimer’s disease

Scientists at the University of Colorado Anschutz have discovered that while brain neuron changes, including cell loss, may begin in early life, a drug long-approved for other conditions might be repurposed to slow this damage, offering new hope for those with Alzheimer's disease (AD) and other cognition issues.

19 Dec 2025