Histology News and Research

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New staining method helps analyze 3D tissue samples using Nano-CT system

To date, examining patient tissue samples has meant cutting them into thin slices for histological analysis. This might now be set to change - thanks to a new staining method devised by an interdisciplinary team from the Technical University of Munich.

23 Feb 2018

Scientists gain better understanding of how the intestine repairs itself after injury

Researchers at Baylor College of Medicine, Johns Hopkins University School of Medicine and the University of California, San Francisco have gained new insights into how the small intestine, one of the fastest renewing tissues in the human body, repairs itself after injury caused by intestinal rotavirus infection.

30 Jan 2018

Researchers reveal pathological mechanisms in congenital myotonic dystrophy

Myotonic dystrophy (DM) is the most common form of genetic muscular dystrophy that begins in adulthood. DM is characterized by progressive muscle wasting and weakness. People with this disorder often have prolonged muscle contractions (myotonic) and are not able to relax certain muscles after use.

12 Dec 2017

Researchers explore new method of destroying tumor cells

Researchers from Lomonosov MSU Faculty of Biology have studied the stages of entosis, a process of cell death when one cell invades the other and gets digested inside of it. Entosis could become a new method of destroying cancer cells.

27 Nov 2017

Study finds specific tumor environment that stimulates cancer cells to metastasize

A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

22 Nov 2017

Scientists discover how tumor environment can trigger metastatic behavior in cancer cells

A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells.

22 Nov 2017

Heart injury triggers irreversible dysregulation that alters cardiosplenic and cardiorenal networks

Heart failure after a heart attack is a global epidemic leading to chronic heart failure pathology. About 6 million people in the United States and 23 million worldwide suffer from this end-stage disease.

15 Nov 2017

FDA approves first targeted cancer treatment based on basket study

The US Food and Drug Administration has announced that it has approved the drug vemurafenib for the treatment of patients with BRAF V600-mutant Erdheim-Chester disease (ECD).

7 Nov 2017

Newly developed tool to analyze synovial tissue may lead to better rheumatoid arthritis therapies

A newly developed tool to analyze the cellular and molecular profiles of synovial tissue and peripheral blood may help unlock clues about rheumatoid arthritis and lead to better therapies, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Digital Pathology for Everyone

There are two problems that pathologists face today. The first is, that a pathologist’s diagnosis using tissue sections is becoming more complex. There are many more biomarkers, and clinicians now ask for a more precise diagnosis. Secondly, the number of pathologists worldwide is declining every day, as the profession is often overlooked in favor of other specializations.

From microDimensions - Bramlage Scientific GmbH 27 Oct 2017

Study offers solution to protect against vaccine-enhanced respiratory disease

Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory disease that results when patients given an early form of a vaccine for respiratory syncytial virus (RSV) are exposed to RSV, according to a study led by Georgia State University.

23 Oct 2017

Researchers use novel imaging technique for precise assessment of spinal degeneration

Research by a Barrow Neurological Institute neurosurgery team on novel imaging technique assessment of patients with lumbar spine degeneration was published in the Aug. 28 issue of PLOS ONE.

20 Oct 2017

Factors associated with disparities in breast cancer survival studied

According to a latest study, several factors are responsible for the differences in the survival statistics of the non-elderly women with breast cancer. For example in 2012, the health reports had revealed that black women have a 43% higher risk of death when affected with breast cancer compared to their white counterparts.

16 Oct 2017

Anyslide by microDimensions provides a cloud-based digital pathology platform

Digital Pathology is happening. While the advantages are evident and experts already predict a new generation of pathologists, only few laboratories and institutes have started planning and investing in fully digital work-flows. At the same time, the demand for professional online exchange and a convenient way of sharing educational or rare cases is growing with the aim to support a more precise and profound health care.

From microDimensions - Bramlage Scientific GmbH 5 Sep 2017

CHLA researchers succeed in better defining rare pediatric malignant liver disease

Investigators at Children's Hospital Los Angeles have succeeded in better defining a rare pediatric malignant liver disease -- a necessary step in achieving an optimum treatment.

9 Aug 2017

Stowers researchers solve 3D structure of critical protein complex using microscopy techniques

Researchers at the Stowers Institute for Medical Research have solved the three-dimensional structure of a complex that is essential for the correct sorting of chromosomes into eggs and sperm during reproductive cell division or meiosis.

2 Aug 2017

Researchers develop new method to visualize whole-body cancer metastasis at single-cell level

Researchers at the RIKEN Quantitative Biology Center and the University of Tokyo have developed a method to visualize cancer metastasis in whole organs at the single-cell level.

6 Jul 2017

Viral vectors for gene transfer can travel to distant areas in the brain, study shows

Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells.

16 Jun 2017

Hybrid molecular imaging system detects vulnerable arterial plaques in earliest stages

A new study shows that a hybrid molecular imaging system unites three imaging modalities to map the composition of dangerous arterial plaques before they rupture and induce a major cardiac event.

12 Jun 2017

Gray matter density increases during transition from childhood to young adulthood, study reveals

For years, the common narrative in human developmental neuroimaging has been that gray matter in the brain - the tissue found in regions of the brain responsible for muscle control, sensory perception such as seeing and hearing, memory, emotions, speech, decision making, and self-control -- declines in adolescence, a finding derived mainly from studies of gray matter volume and cortical thickness (the thickness of the outer layers of brain that contain gray matter).

26 May 2017