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AP-1 proteins help cancer cells rewire genes to survive treatment

A long-standing mystery in cancer treatment is how tumor cells so often become resistant to drugs, even ones they have never encountered before.

15 Apr 2026

Brain organoids reveal mutation-specific insights for Rett syndrome

Though many studies approach the developmental disorder Rett syndrome as a single condition arising from general loss of function in the gene MECP2, a new study by neuroscientists in The Picower Institute for Learning and Memory at MIT shows that two different mutations of the gene caused many distinct abnormalities in lab cultures.

15 Apr 2026

Ultrasensitive assay uncovers hidden burden of tuberculosis disease

Researchers at Boston University have discovered an unexpectedly high prevalence of Mycobacterium tuberculosis DNA (TB DNA) in patients hospitalized in Boston, suggesting that tuberculosis disease may be significantly underdiagnosed in the United States.

14 Apr 2026

Eardrum perforations and cholesteatoma linked to higher odds of dementia

A new study published in Otolaryngology–Head and Neck Surgery, the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF), finds that two common and treatable causes of conductive hearing loss-eardrum perforations and cholesteatoma, a type of abnormal skin growth in the middle ear-are associated with higher odds of dementia.

13 Apr 2026

Minimally-invasive stenting effectively treats painful post-thrombotic syndrome

A major multi-site clinical trial co-led by researchers at Washington University School of Medicine in St. Louis has shown that post-thrombotic syndrome - a common and often painful complication suffered by many people who have experienced blockages of major veins due to blood clots - can be effectively treated with a minimally invasive procedure.

13 Apr 2026

Microneedle nanoparticle platform improves lymphatic imaging with high resolution

The lymphatic system plays a critical role in pathological conditions such as lymphedema and chronic inflammation to tumor metastasis, venous insufficiency, and impaired wound healing, making accurate evaluation of its structure and function increasingly important.

13 Apr 2026

Researchers identify cellular changes in motor control following spinal injury

Even when people with incomplete spinal cord injuries can walk, everyday functions like standing, balancing or producing steady force may remain difficult. A new study shows why.

13 Apr 2026

Metformin protects neurons after brain injury by restoring mitochondrial health

TBI remains a major cause of death and long-term neurological disability worldwide, yet effective treatments for secondary injury are still lacking.

13 Apr 2026

Obesity health risks differ significantly between men and women

New research being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May), reveals distinct patterns of heart, metabolic, and inflammatory health risks between men and women living with obesity, providing an insight into how clinicians may be able to tailor management approaches.

13 Apr 2026

Novel antibiotic compound shows promise against MRSA skin infections

The development of new antibiotics to treat superbugs and other bacterial infections is a global priority, with the rate of infections that cannot be treated with current antibiotics rising and presenting one of the biggest threats to human health.

11 Apr 2026

PRRDetect algorithm could one day revolutionize the treatment of cancer

Researchers have created a "metal detector" algorithm called PRRDetect to hunt down vulnerable tumors, in a development that could one day revolutionize the treatment of cancer.

11 Apr 2026

Sylvester Comprehensive Cancer Center opens new trial for neuroendocrine tumors

A clinical trial for patients with high-grade neuroendocrine tumors is now open for enrollment at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

10 Apr 2026

Wildlife trade increases risk of disease transmission to humans

From lemurs to fennec foxes, wild animals are bought and sold around the world-legally and illegally, dead and alive-including as pets, for food and for traditional medicinal uses.

9 Apr 2026

FTC drug divestiture policy may reduce competition, study finds

Last month, Novartis completed its $11 billion acquisition of Avidity Biosciences-the latest in a string of major pharmaceutical mergers including Merck's acquisition of Verona Pharma and GSK's acquisition of RAPT Therapeutics.

9 Apr 2026

Low oxygen triggers regenerative programs in mammalian limb cells

Some animals can regrow lost body parts. Salamanders and frog tadpoles can rebuild entire limbs after amputation. Mammals cannot. For decades, biologists have tried to understand why.

9 Apr 2026

AI-powered chemistry accelerates discovery of selective cancer inhibitors

Recently, the Insilico team's research entitled "An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potential and Sub-Family Selective PKMYT1 Inhibitors" was invited for publication as a cover Feature in ChemMedChem.

9 Apr 2026

Korean skincare ingredient emerges as potential antibiotic candidate

Fans of Korean skincare may be familiar with 'hero ingredient' Madecassic acid for its skin-soothing properties, but researchers at the University of Kent have revealed its greater potential for use in the battle against antibiotic resistance.

9 Apr 2026

Preconditioned skin cells enable faster and more effective wound healing

It is well known that students who prepare in advance perform better on exams. Now, it appears that the skin can do the same.

8 Apr 2026

New monoclonal antibody shows promise for preventing Lyme disease

A Phase I clinical trial of a human monoclonal antibody discovered and developed at UMass Chan Medical School for the prevention of Lyme disease in the U.S. was well tolerated and showed lasting serum concentrations in participants, according to data presented by Mark Klempner, MD, at the World Vaccine Congress 2026 in Washington D.C.

8 Apr 2026

Study finds unisex armor can trap more blast energy on female torsos

Researchers used free-field C4 blasts and anatomically representative male and female manikins to test how unisex SAPI body armor changes shock exposure under different blast angles. They found that while armor lowered peak pressure in both, the female torso shape created larger air gaps that trapped energy longer and increased impulse exposure, especially around the underbust region.

6 Apr 2026