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'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

Age-related macular degeneration is one of the most common causes of vision loss in people over age 65.

10 May 2019

Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogens

Insights into the genes and proteins involved in the predatory behavior of a parasitic yeast species could lead to new strategies for controlling yeast pathogens, according to a study published May 9 in the open-access journal PLOS Pathogens by Jürgen Wendland of the Carlsberg Research Laboratory in Denmark and Vrije Universiteit Brussel in Belgium, and colleagues.

10 May 2019

Computational tool uses patient's genomic data to find best treatment for bladder cancer

When it comes to cancer, one-size-does-not-fit-all.One of the challenges that we have when taking care of patients with bladder cancer is that from one patient to the next, the prognosis, the stage and the response to different kinds of treatment differ.

10 May 2019

Small molecule drug may help overcome ibrutinib resistance in mantle cell lymphona

A study at The University of Texas MD Anderson Cancer Center demonstrated how a small molecule drug discovered at the institution may help overcome resistance to treatment with ibrutinib in patients with mantle cell lymphoma.

9 May 2019

Genomics study reveals five genes linked to treatment resistance in prostate cancer

A new genomics study has found that men are three times more likely to die from prostate cancer if they possess mutations the retinoblastoma 1 (RB1) gene.

8 May 2019

Researchers create ‘mini-guts’ to explore how gut epithelium respond to gluten in celiac patients

In pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Center at Massachusetts General Hospital have validated the use of intestinal organoids.

8 May 2019

Circulating tumor DNA can help detect treatment options for ovarian cancer subtype

According to a new research, circulating tumor DNA can be used detect treatment options for ovarian cancer patients who don't benefit from chemotherapy.

6 May 2019

Genetic test for low birth weight on the horizon

Researchers have successfully identified 190 genetic factors associated with a low birth weight. They hope that this may one day be used to develop a universal genetic test.

3 May 2019

Blocking pro-cancer protein could be 'unexpectedly effective' in treating malignant rhabdoid tumor

Malignant rhabdoid tumor is one of the most aggressive and lethal childhood cancers.

2 May 2019

Biomarker may help predict first treatment option for metastatic colorectal cancer patients

Foundational research by a City of Hope physician-scientist and his colleagues could one day help metastatic colorectal cancer patients decide whether to choose immunotherapy or chemotherapy as their first treatment option.

2 May 2019

Sussex scientists discover new genetic defect that causes intellectual disability

Researchers at the University of Sussex have discovered a new genetic defect which causes a form of intellectual disability; a finding that will improve screening programmes and help to end a 'diagnostic odyssey' for families across the globe.

1 May 2019

Updated ASTRO/AUA Guideline on adjuvant and salvage radiotherapy after prostatectomy

The American Society for Radiation Oncology and the American Urological Association today announced updates to their joint clinical guideline on adjuvant and salvage radiotherapy after prostatectomy in patients with and without evidence of prostate cancer recurrence to include new published research related to adjuvant radiotherapy.

1 May 2019

Children under 3 years old are most vulnerable to the effects of adversity, study finds

A Massachusetts General Hospital study has found evidence that children under 3 years old are most the vulnerable to the effects of adversity - experiences including poverty, family and financial instability, and abuse - on their epigenetic profiles, chemical tags that alter gene expression and may have consequences for future mental health.

1 May 2019

Angiotensin receptor blockers could improve response to cancer immunotherapy

A research team led by investigators at Massachusetts General Hospital and the Massachusetts Institute of Technology has found that combining a specialized version of an antihypertension drug with immune checkpoint blockers could increase the effectiveness of cancer immunotherapies.

30 Apr 2019

Precision medicine for pediatric tumors can now be a reality, shows study

Five years after it was created to serve children and adolescents in Quebec, the TRICEPS team at CHU Sainte-Justice has demonstrated the feasibility of setting up a research program in pediatric oncology precision medicine, as described in a recent article published in the JAMA Network Open journal.

30 Apr 2019

UAB professor honored with the most prestigious prize for research in polycystic kidney disease

Bradley K. Yoder, Ph.D., professor and chair of the Department of Cell, Developmental and Integrative Biology at the University of Alabama at Birmingham, has been awarded with a Lillian Jean Kaplan International Prize for Advancement for his significant research in the polycystic kidney field.

29 Apr 2019

Women pay more for over-the-counter facial moisturizing products, MGH study finds

Over-the-counter facial moisturizers are a widely-used and commonly recommended skin care product, but a new study from dermatologists at Massachusetts General Hospital finds that, when it comes to price, men's and women's products are not considered equal.

29 Apr 2019

Genomic News and Research

'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

Insights into parasitic yeast species could lead to new strategies for controlling yeast pathogens

Computational tool uses patient's genomic data to find best treatment for bladder cancer

Small molecule drug may help overcome ibrutinib resistance in mantle cell lymphona

Genomics study reveals five genes linked to treatment resistance in prostate cancer

Researchers create ‘mini-guts’ to explore how gut epithelium respond to gluten in celiac patients

Circulating tumor DNA can help detect treatment options for ovarian cancer subtype

Genetic test for low birth weight on the horizon

Blocking pro-cancer protein could be 'unexpectedly effective' in treating malignant rhabdoid tumor

Biomarker may help predict first treatment option for metastatic colorectal cancer patients

Sussex scientists discover new genetic defect that causes intellectual disability

Updated ASTRO/AUA Guideline on adjuvant and salvage radiotherapy after prostatectomy

Children under 3 years old are most vulnerable to the effects of adversity, study finds

Angiotensin receptor blockers could improve response to cancer immunotherapy

Precision medicine for pediatric tumors can now be a reality, shows study

UAB professor honored with the most prestigious prize for research in polycystic kidney disease

Women pay more for over-the-counter facial moisturizing products, MGH study finds

New study aims to determine underlying etiology of seizures and reduce morbidities in children

New study describes process to diagnose rare genetic diseases in record time

Oncotype DX-guided treatment could reduce cost for breast cancer care, study suggests

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