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SARS-CoV-2 immune memory in mRNA vaccine recipients

Researchers measured SARS-CoV-2–specific antibody, memory B cell, and memory T cell responses in a group of healthy subjects who generated primary immune responses to two doses of mRNA vaccine compared to a group of SARS-CoV-2–recovered vaccines.

6 Dec 2021

Probiotics significantly improve the symptoms of pregnancy-related problems

In a first-of-its-kind study, researchers at the UC Davis School of Medicine found that probiotics significantly improve the symptoms of pregnancy-related nausea, vomiting and constipation. The findings were published in the journal Nutrients.

6 Dec 2021

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

A novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.

5 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021

Study reveals source of the brain's resting energy drain

Pound for pound, the brain consumes vastly more energy than other organs, and, puzzlingly, it remains a fuel-guzzler even when its neurons are not firing signals called neurotransmitters to each other.

4 Dec 2021

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

SARS-CoV-2 causes the pandemic coronavirus disease COVID-19, that is more harmful for elderly people, who show more severe symptoms and are at higher risk of hospitalization and death.

3 Dec 2021

Quantum mechanical model offers insights into SARS-CoV-2 evolution

Researchers used an ab initio full quantum mechanical model to characterize the spike protein RBD interactions with host cells and gain mechanistic insights into SARS-CoV-2 evolution.

3 Dec 2021

CRISPR-based DETECTR® assay for faster SARS-CoV-2 surveillance

Researchers from the USA discuss the development and validation of CRISPR-Cas12-based COVID-19 variant DETECTR® assay for the detection of SARS-CoV-2.

3 Dec 2021

Novel peptide-antibody fusion molecule enhances SARS-CoV-2 variant neutralization

A recent study reports neutralizing efficacy for a fused peptide-antibody molecule against SARS-CoV-2, providing hope that therapeutic neutralizing antibodies may soon be available.

3 Dec 2021

Link between tobacco product use and alcohol consumption with anti-SARS-CoV-2 antibody titers after BNT162b2 vaccine

In a Japanese study, smoking, HNB tobacco products, and alcohol use have been shown to impair the immunological response to the COVID-19 vaccination.

2 Dec 2021

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Researchers investigate the antiviral activities of SSPS extracted from green seaweed Ulva sp. to demonstrate the anti-SARS-CoV-2 activity of ulvans.

2 Dec 2021

New bioinformatics method for viral sgRNA analysis

A recent study discusses a bioinformatics method to help identify and explore sgRNAs uncovered in next-generation sequencing data.

2 Dec 2021

Impact of SARS-CoV-2 infection on testis function

A study published in the journal Nature Reviews Urology discusses the impact of coronavirus disease 2019 (COVID-19) on male fertility.

2 Dec 2021

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

Researchers report antibody cocktails are promising candidate tools for controlling new SARS-CoV-2 variants

Researchers from Academia Sinica in Taiwan have been investigating new antibodies that could have strong effects against SARS-CoV-2 infection.

2 Dec 2021

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

In new studies, researchers concluded that licorice triterpenoids could be candidates for anti-SARS-CoV-2 drug developments.

2 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

Study could lead to new strategies to prevent or slow Alzheimer's disease

A gene mutation linked to Alzheimer's disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new study by scientists at Weill Cornell Medicine.

1 Dec 2021

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Researchers employ a structure-guided approach for the development of a series of ACE2-Fc variants using human IgG1 or IgG3 backbone.

1 Dec 2021

Structure function analysis of potent antibodies against Beta SARS-CoV-2 variant

A team of researchers from UK and US institutions created a large panel of mAbs derived from memory B cells of convalescent Beta subjects to better understand the antigenic landscape of Beta.

1 Dec 2021

Enzyme News and Research

SARS-CoV-2 immune memory in mRNA vaccine recipients

Probiotics significantly improve the symptoms of pregnancy-related problems

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

Study reveals source of the brain's resting energy drain

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

Quantum mechanical model offers insights into SARS-CoV-2 evolution

CRISPR-based DETECTR® assay for faster SARS-CoV-2 surveillance

Novel peptide-antibody fusion molecule enhances SARS-CoV-2 variant neutralization

Link between tobacco product use and alcohol consumption with anti-SARS-CoV-2 antibody titers after BNT162b2 vaccine

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

New bioinformatics method for viral sgRNA analysis

Impact of SARS-CoV-2 infection on testis function

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Researchers report antibody cocktails are promising candidate tools for controlling new SARS-CoV-2 variants

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Study could lead to new strategies to prevent or slow Alzheimer's disease

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Structure function analysis of potent antibodies against Beta SARS-CoV-2 variant

Measuring Drug-Target Residence Times with Biochemical Assays eBook

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