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Drug accumulation alters gut bacterial metabolism and composition

In a research paper recently published in the journal Nature by Klünemann et al. (September 8th, 2021), the interaction of 15 diverse drugs with 25 common strains of gut bacteria is investigated, revealing 70 bacteria-drug interactions that include 29 entirely novel mechanisms not yet reported.

15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Researchers in the United States have developed a new automated approach to detecting variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that have increased growth rates over other lineages.

15 Sep 2021

Impact of prior SARS-CoV-2 infection and vaccine on antibody levels: Texas survey

A collaborative team, led by principal investigator Dr. Eric Boerwinkle, at The University of Texas Health Science Center at Houston, School of Public Health is conducting a survey designed to assess the frequency of antibody-positive individuals across Texas. The TEXAS Coronavirus Antibody REsponse Survey (CARES) aims to look for antibodies in the blood made in response to natural SARS-CoV-2 infection or vaccination.

14 Sep 2021

A review of mesenchymal stem cell therapy for severe COVID-19

Researchers find that MSC treatment is highly tolerated and effective in reducing lung damage in COVID-19 patients and improving their chances of recovery.

13 Sep 2021

COVID-19 lockdown linked to improved glycemic control in type 1 diabetes

A new study looks at changes in the glycemic control in patients with diabetes during the lockdowns implemented to deal with the COVID-19 pandemic.

13 Sep 2021

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

In a recent study, authors explore the relationship between age and immune response to COVID-19.

13 Sep 2021

Does SARS-CoV-2 contamination in operating and birthing room settings pose risks for health care workers?

A new study assesses the risk of contamination in the operating room and birthing suite environment.

13 Sep 2021

Urban and deprived individuals are disproportionately afflicted by COVID-19

In a recent study, scientists at the University of Oxford investigate the risk for SARS-CoV-2 infection in various populations.

13 Sep 2021

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Scientists were inspired by the robust serum nAb responses in people who recovered from natural SARS-CoV-2 infection and were later vaccinated using mRNA vaccine. They isolated and characterized bnAbs from two COVID-19 convalescent donors who were recently vaccinated. These isolated bnAbs were found to be highly potent against sarbecoviruses. This research is available on the bioRxiv* preprint server.

13 Sep 2021

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

A recent study, currently available on the bioRxiv* preprint server, reveals that a specific region of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be targeted by antisense oligonucleotides to potently inhibit viral replication, and consequently the development of coronavirus disease (COVID-19).

12 Sep 2021

School children in Switzerland show willingness to mask-wearing

A school-based survey has revealed that about 60% of students in Zurich perceive mask-wearing at school as a useful intervention for controlling SARS-CoV-2 transmission.

10 Sep 2021

SARS-CoV-2 transmission dynamics in Nordic countries

Scientists have recently assessed the strategies adopted by the Nordic countries to curb the trajectory of the COVID-19 pandemic.

10 Sep 2021

Breastfeeding women and their babies: the outcomes after mRNA COVID-19 vaccination

Scientists evaluated the effect of vaccination in breastfeeding women and its possible effects in infants in a study involving 180 fully vaccinated, breastfeeding women.

10 Sep 2021

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

A group of researchers analyzed the B cell response to SARS-CoV-2 in unexposed individuals.

10 Sep 2021

Study identifies predictors of hospitalizations or emergency department encounters for older people

One in five South Australians will experience an unplanned hospitalization or emergency department presentation within 90 days of undertaking an aged care assessment, according to new research by the University of South Australia and the South Australian Health and Medical Research Institute.

9 Sep 2021

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

Researchers in Japan have warned that the Mu (B.1.621) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – appears to be highly resistant to neutralization by sera from convalescent or vaccinated individuals.

8 Sep 2021

Study finds no serious side effects of mRNA COVID-19 vaccines in lactating women, breastfed infants

In December 2020, two novel messenger RNA (mRNA) vaccines for SARS-CoV-2 received emergency use authorization from the U.S. Food and Drug Administration; however, the early trials excluded lactating women, leading to questions about their safety in this specific population.

8 Sep 2021

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

About a quarter of the world's population is infected with tuberculosis bacteria, according to the World Health Organization, but only about 5 to 10% of those infected will develop symptoms. These pathogens are mycobacteria, which are everywhere, including in chlorine-treated tap water.

8 Sep 2021

Increase in social stress may be connected to global population decline

A University of Massachusetts Amherst environmental health scientist has developed an "overlooked hypothesis" to help explain the projected global population decline beginning in 2064: social stress.

7 Sep 2021

Frequency News and Research

Drug accumulation alters gut bacterial metabolism and composition

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Impact of prior SARS-CoV-2 infection and vaccine on antibody levels: Texas survey

A review of mesenchymal stem cell therapy for severe COVID-19

COVID-19 lockdown linked to improved glycemic control in type 1 diabetes

Age-related differences in immune dynamics in rhesus macaques infected with SARS-CoV-2

Does SARS-CoV-2 contamination in operating and birthing room settings pose risks for health care workers?

Urban and deprived individuals are disproportionately afflicted by COVID-19

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

School children in Switzerland show willingness to mask-wearing

SARS-CoV-2 transmission dynamics in Nordic countries

Breastfeeding women and their babies: the outcomes after mRNA COVID-19 vaccination

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

Study identifies predictors of hospitalizations or emergency department encounters for older people

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

Study finds no serious side effects of mRNA COVID-19 vaccines in lactating women, breastfed infants

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

Increase in social stress may be connected to global population decline

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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