Anal Cancer News and Research

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Anal cancer is a type of cancer which arises from the anus, the distal orifice of the gastrointestinal tract. It is a distinct entity from the more common colorectal cancer.

HPV-related cancers increase in U.S. counties with low-income, high smoking prevalence

A new paper in JNCI Cancer Spectrum, published by Oxford University Press, finds increases in both men and women for several HPV-related cancers in low-income counties or those with high smoking rates. Increases were slower in the highest-income US counties or those with low smoking rates.

3 Mar 2022

Time of starting antiretroviral therapy can influence tumor development In HIV patients

HIV patients have an increased risk of developing skin and mucosal cancers, even though HIV is no longer detectable in their blood due to antiretroviral therapy.

23 Nov 2021

Removing high-grade squamous intraepithelial lesions reduces chances of progression to anal cancer

In a randomized clinical trial with 4,446 participants, known as the Anal Cancer/HSIL Outcomes Research (ANCHOR) study, researchers found that by removing high-grade squamous intraepithelial lesions (HSIL), chances of progression to anal cancer were significantly reduced.

8 Oct 2021

Mount Sinai awarded more than $4 million to evaluate anal cancer screening in high-risk women

The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million by the National Cancer Institute for a large-scale study to evaluate anal cancer screening in high-risk women who have been previously diagnosed with human papillomavirus (HPV) infection.

10 Aug 2021

Vaccination program reduces HPV-related diseases in gay, bisexual men

A study by Monash University and Alfred Health found a 70 per cent reduction in one type of human papillomavirus (HPV) in gay and bisexual men after the implementation of the school-based HPV vaccination program.

26 May 2021

Study: Anal intraepithelial neoplasia is a precursor lesion for anal squamous cell carcinomas

Oncotarget recently published "PD-1/PD-L1 expression in anal squamous intraepithelial lesions" which reported that the presence and distribution of CD8 lymphocytes and the presence of PD-1 lymphocytes and PD-L1 epithelial cells were assessed.

12 Jan 2021

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

The first randomized phase 3 clinical trial ever to be conducted in patients with advanced cancer of the anal canal is now open and enrolling patients.

16 Nov 2020

Study shows potential of new pinprick blood test for diagnosing HPV-related cancers

A potential breakthrough in the early detection of the neck, head and anal cancers linked to human papilloma viruses has emerged.

12 Nov 2020

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives--but an unfortunate consequence of people living longer with HIV is an increased risk of cancer.

22 Sep 2020

International trial shows better option for treating people with inoperable anal cancer

People with inoperable anal cancer treated with carboplatin-paclitaxel had fewer complications and lived longer than those who received another chemotherapy that has been more often administered.

24 Jun 2020

Study finds carboplatin-paclitaxel as the optimal chemotherapy for anal cancer

Up to now, patients with inoperable anal cancer, a rare disease, have not had a standard-of-care treatment; palliative care has been the routine for them.

19 Jun 2020

Young sexual minority men do not fully understand their risk for HPV infection

Young sexual minority men -- including those who are gay, bisexual, queer or straight-identified men who have sex with men -- do not fully understand their risk for human papillomavirus due to a lack of information from health care providers, according to Rutgers researchers.

11 Feb 2020

NCCN Patient Advocacy Summit closes gaps in perspective of value in cancer care

The National Comprehensive Cancer Network (NCCN) hosted an annual NCCN Patient Advocacy Summit: Delivering Value for Patients across the Oncology Ecosystem in Washington, DC, today.

11 Dec 2019

Anal cancer diagnoses and death rates have increased dramatically over the last 15 years

Rates of new anal cancer diagnoses and deaths related to human papillomavirus, the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston.

19 Nov 2019

Study: Most U.S. adults are unaware that HPV causes anal, penile, and oral cancers

More than 70% of U.S. adults are unaware that human papillomavirus causes anal, penile, and oral cancers, according to an analysis led by researchers at The University of Texas Health Science Center at Houston School of Public Health and published in the current issue of JAMA Pediatrics.

16 Sep 2019

Anal Cancer News and Research

Further Reading

HPV-related cancers increase in U.S. counties with low-income, high smoking prevalence

Time of starting antiretroviral therapy can influence tumor development In HIV patients

Removing high-grade squamous intraepithelial lesions reduces chances of progression to anal cancer

Mount Sinai awarded more than $4 million to evaluate anal cancer screening in high-risk women

Vaccination program reduces HPV-related diseases in gay, bisexual men

Study: Anal intraepithelial neoplasia is a precursor lesion for anal squamous cell carcinomas

First-ever phase 3 advanced anal cancer trial opens for patient enrollment

Study shows potential of new pinprick blood test for diagnosing HPV-related cancers

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

International trial shows better option for treating people with inoperable anal cancer

Study finds carboplatin-paclitaxel as the optimal chemotherapy for anal cancer

Young sexual minority men do not fully understand their risk for HPV infection

NCCN Patient Advocacy Summit closes gaps in perspective of value in cancer care

Anal cancer diagnoses and death rates have increased dramatically over the last 15 years

Study: Most U.S. adults are unaware that HPV causes anal, penile, and oral cancers

New test may improve the ability to diagnose riskiest forms of HPV infection

Prevalence of anal cancer precursors is higher in women living with HIV than previously reported

HPV vaccination rates are low, especially in HIV prone populations

New immune-based therapy eliminates HPV in one-third of women with cervical precancerous lesions

Study finds critically low HPV vaccination rates among younger adolescents in the U.S.

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