Doxorubicin News and Research

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Doxorubicin hydrochloride is approved for use with other drugs as adjuvant therapy for breast cancer that has spread to the lymph nodes, including cancer that is HER-2 positive or has spread after surgery.

In addition to the uses that have been approved by the FDA, doxorubicin hydrochloride is sometimes used alone or with other drugs to treat other types of cancer. The drug continues to be studied in the treatment of many types of cancer.

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

This study shows that vacancy-engineered MoS₂ nanoflowers drive mitochondrial biogenesis in human mesenchymal stem cells by activating SIRT1–PGC-1α signaling and reducing oxidative stress. These treated cells transfer more functional mitochondria to injured recipient cells, restoring energy metabolism and redox balance in multiple in vitro models.

9 Dec 2025

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Most patients with a rare and aggressive form of large B-cell lymphoma can safely receive a less toxic treatment than the intensive chemotherapy often used, according to new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

8 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

Advancements and clinical translation of intelligent nanodrugs for breast cancer treatment

A comprehensive review in "Biofunct. Mater." meticulously details the most recent advancements and clinical translation of intelligent nanodrugs for breast cancer treatment.

24 Oct 2025

A new way to monitor chemotherapy drug behavior inside cells

Scientists have made incredible progress in developing cancer therapies that help patients across cancer types.

22 Oct 2025

Multimodal nanocarriers offer targeted solutions for tumor treatment

Cancer remains a leading cause of global morbidity and mortality. Traditional therapies like chemotherapy and radiotherapy are often limited by their lack of specificity, leading to systemic toxicity and the emergence of drug resistance.

10 Oct 2025

Cyclic peptide nanotubes offer new route to overcome cancer drug resistance

A research team at CiQUS (University of Santiago de Compostela, Spain) has unveiled an innovative molecular approach that enables anticancer drugs to reach the nucleus of tumor cells, where they can exert their therapeutic effect.

10 Oct 2025

Magnetically-powered nanorobots enhance drug uptake in tumors

Spiky nanorobots powered by magnets have been developed to carry drugs and pierce tumor cell membranes, a key barrier to effective cancer treatment. By boosting drug entry, these "microscopic scalpels" improved chemotherapy results in laboratory and animal studies, suppressing tumor growth and extending survival.

22 Sep 2025

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Using tiny particles shaped like bottlebrushes, MIT chemists have found a way to deliver a large range of chemotherapy drugs directly to tumor cells.

10 Sep 2025

Researchers investigate how citrus bioflavonoid naringin could reduce inflammation and heart risk

Researchers reviewed 62 studies on naringin, a citrus flavonoid, and found strong preclinical evidence for its cardioprotective effects, including improved endothelial function, reduced oxidative stress, and protection against myocardial injury.

18 Aug 2025

Nanobody breakthrough offers precise targeting of lung cancer cells

A research team led by Dr. Juyeon Jung at the Bio-Nano Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), has developed a nanobody-based technology that can precisely identify and attack only lung cancer cells, opening new possibilities for cancer therapy.

17 Aug 2025

Lauric acid could be a key cancer-fighting compound in coconut oil

Virgin coconut oil and lauric acid show promise in inhibiting cancer cell growth and mitigating chemotherapy toxicity, paving the way for future therapies.

11 Aug 2025

Chemotherapy treatment linked to lasting cognitive changes in rats

Researchers at The City College of New York have linked chemotherapy treatment to lasting cognitive changes in rats – potentially shading light, for the first time, on cognitive problems some cancer survivors experience long after treatment ends.

31 Jul 2025

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

Researchers engineered a nanobody-conjugated liposome (A5-LNP-DOX) that targets CD155 and delivers doxorubicin directly to lung adenocarcinoma cells, dramatically suppressing tumor growth in preclinical models. This approach not only inhibited cancer cell migration and invasion but also showed strong potential for safer, more precise lung cancer therapy.

14 Jul 2025

Doxorubicin News and Research

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Innovative research reveals FGD3 as a key player in breast cancer cell death

Advancements and clinical translation of intelligent nanodrugs for breast cancer treatment

A new way to monitor chemotherapy drug behavior inside cells

Multimodal nanocarriers offer targeted solutions for tumor treatment

Cyclic peptide nanotubes offer new route to overcome cancer drug resistance

Magnetically-powered nanorobots enhance drug uptake in tumors

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Researchers investigate how citrus bioflavonoid naringin could reduce inflammation and heart risk

Nanobody breakthrough offers precise targeting of lung cancer cells

Lauric acid could be a key cancer-fighting compound in coconut oil

Chemotherapy treatment linked to lasting cognitive changes in rats

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

ALKBH3 regulates glycolysis and doxorubicin resistance in triple negative breast cancer

KAIST scientists develop tool to fight drug resistance in cancer

New genomic test predicts chemotherapy resistance in cancer patients

New nanoparticle system improves drug delivery for cancer treatment

Unmasking Nrf2 as a key driver of treatment resistance in osteosarcoma

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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