Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

New V-UNet model improves efficient medical image segmentation

Segmentation tools help doctors identify and delineate tumors, lesions, and other abnormalities in medical images.

4 Sep 2026

Scientists develop lab-grown heart tissue model for heart failure

Scientists study the underlying causes of a disease or test new potential drugs in animal models or cells obtained from human biopsy specimens before clinical trials.

2 Sep 2026

Insilico Medicine releases frontier AI models for drug discovery

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced the release of a series of frontier specialist models for chemistry and biology, trained through its MMAI Gym for Science framework.

2 Sep 2026

Harvard scientists discover entirely new gene regulation system in mammals

For decades, scientists have understood that each of the roughly 20,000 genes in the human body carries the instructions for a single kind of protein.

2 Sep 2026

New tool amplifies and visualizes tiny protein changes

Imagine a brain teaser where the challenge is to spot the difference between two nearly identical sandcastles.

1 Sep 2026

AI platform uncovers new molecular targets for Alzheimer's disease

Groundbreaking study published in Alzheimer's & Dementia reveals the crucial links between the NAD⁺-mitophagy axis and neurodegeneration.

1 Sep 2026

Funding boost to strengthen Australia's drug discovery pipeline

A WEHI-led project has received $7 million in Australian Government funding to expand the nation’s drug discovery capabilities and accelerate the translation of breakthrough research into new therapies.

26 Aug 2026

Ancient proteins revived to inspire new antimicrobial treatments

University of Oregon biologists have resurrected prehistoric proteins up to 160 million years old that carry natural antimicrobial properties.

25 Aug 2026

Scientists discover how neutrophils travel to infection sites without damaging healthy tissue

UMass Chan Medical School scientist Beth McCormick, PhD, and her team collaborated with researchers at the University of Bath to discover how neutrophils, the body's most abundant type of white blood cells, travel to infection sites without damaging healthy tissue.

25 Aug 2026

Targeting cyclin-dependent kinases offers new pathways for cancer therapy

Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that target the uncontrolled growth of tumor cells, a class of enzymes known as cyclin-dependent kinases (CDKs) has come into focus.

24 Aug 2026

Study confirms benefits of robotic gastric cancer surgery

Surgery remains the primary curative treatment for gastric cancer, with laparoscopic gastrectomy (LG) established as a standard minimally invasive approach.

24 Aug 2026

Glioma microenvironment emerges as key target for future therapies

The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and temozolomide chemotherapy, with median survival rarely exceeding 15 to 18 months.

20 Aug 2026

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The ELRIG Mid-Career Initiative supports scientists in drug discovery, addressing unique challenges and fostering leadership development for career transitions.

20 Aug 2026

AI-driven drug-target interaction prediction moves toward real-world workflows

Drug-target interaction prediction can help researchers explain mechanisms of action, identify candidate targets, reposition existing medicines and prioritize compounds before costly laboratory work.

20 Aug 2026

Researchers map DNA's physical code using large-scale simulations

Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different genes. For regulatory proteins to reach these genes, DNA must be accessible.

20 Aug 2026

Vibration isolation in drug discovery research

Vibration isolation supports high-resolution microscopy in drug discovery, enabling stable imaging environments and reliable data at the nanometer scale.

From TMC Vibration Control 20 Aug 2026

Sino Biological launches European newsletter campaign with exclusive welcome gifts

Sino Biological has launched a special Newsletter Registration Campaign exclusively for customers in Europe, offering researchers and life science professionals an exciting opportunity to stay connected with the latest scientific updates while receiving a complimentary welcome gift, which may be an adorable Snail Plushie Set or an Amazon Gift Card.

From Sino Biological Inc. 13 Aug 2026

Insilico Medicine nominates powerful oral drug candidate for the management of heart risks

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced the nomination of ISM0900, a potent, AI-driven, highly selective, orally available small molecule inhibitor of lipoprotein(a), or Lp(a), as a preclinical candidate (PCC) for the management of cardiovascular risks.

12 Aug 2026

Molecular mapping reveals hidden cellular programs in heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

12 Aug 2026

CN Bio awarded Innovate UK grant to reduce animal use in pharmacokinetic studies

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced it has been awarded £180 k grant funding from Innovate UK.

From CN Bio 12 Aug 2026