Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Hyponatremia risk varies among individual second-generation antipsychotic drugs

Antipsychotics are used to treat schizophrenia, along with bipolar disorder and major depressive disorder. However, these medications can be associated with hyponatremia, a serious reduction in blood sodium levels.

8 Oct 2026

ELRIG and The Protein Society announce keynote speakers for Protein Sciences in Drug Discovery 2026

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, and The Protein Society, an international, not-for-profit, scholarly society, with the mission to provide forums for the advancement of research into protein structure, function, design and applications, today announced the keynote speakers for Protein Sciences in Drug Discovery 2026.

From ELRIG (UK) Ltd. 8 Oct 2026

Carterra advances lab-in-the-loop drug discovery through new scientific collaboration

Carterra®, a leading provider of high-throughput surface plasmon resonance (HT-SPR™) platforms for antibody and small molecule drug discovery, today announced a research collaboration with AstraZeneca to develop hardware and software aimed at advancing lab-in-the loop drug discovery.

From Carterra Inc. 8 Oct 2026

Scientists discover a novel strategy to unmask cancer cells in high-risk neuroblastoma

High-risk neuroblastoma is one of the most aggressive forms of solid tumors affecting children, originating in the nervous system.

6 Oct 2026

Managing misfolded proteins to prevent Parkinson’s disease

The protein alpha-synuclein is abundant in healthy brains and plays an important role in enabling communication between nerve cells. However, under certain conditions, misfolded alpha-synuclein proteins can accumulate into toxic clumps inside neurons

6 Oct 2026

BioDuro appoints Greg Makara as Senior Vice President Lead Discovery Chemistry to strengthen early drug discovery capabilities

BioDuro, a global integrated contract research, development and manufacturing organization (CRDMO), today announced the appointment of Greg Makara, Ph.D., as Senior Vice President Lead Discovery Chemistry.

From BioDuro 5 Oct 2026

CN Bio announces expert speaker line-up and scientific program for inaugural Organ-on-a-chip e-Symposium

CN Bio, a leading Organ-on-a-chip (OOC) company de-risking drug discovery and development pipelines by enabling earlier, more confident decision-making, today announced the full scientific program for the 2026 'From Insight to Decision' e-Symposium.

From CN Bio 5 Oct 2026

Dr. GPCR and Eurofins Discovery join forces to advance GPCR drug discovery

Dr. GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced a strategic partnership with Eurofins Discovery, the drug discovery services side of the same group behind the Eurofins DiscoverX products many in the community already know.

From Eurofins Discovery 5 Oct 2026

Fluorescent sensors could help researchers see diabetes in action

Researchers from the University of Bath have developed fluorescent molecular probes that can detect changes in glucose levels inside living animals, giving scientists new ways of visualizing sugar uptake, studying diabetes, cancer and other metabolic diseases in whole organisms in real time.

1 Oct 2026

Streamlining CRISPR workflows, from editing to analysis

INTEGRA's automated solutions optimize CRISPR workflows, enhancing gene editing efficiency and accelerating the path to innovative therapeutic developments.

From INTEGRA Biosciences 30 Sep 2026

MolBoolean™ measures free and bound proteins in the same experiment

Atlas Antibodies has launched MolBoolean™, a new in situ proximity assay. It detects free protein A, free protein B, and the A–B complex together in fixed cells and tissue.

From Atlas Antibodies AB 30 Sep 2026

An AI-identified biomarker can look accurate and still fail its biggest test

The review examines how AI combines molecular, imaging, circulating, cellular, and digital data to identify potential disease biomarkers. Its authors argue that independent validation, biological testing, and evidence of better clinical decisions are needed before those candidates enter patient care.

28 Sep 2026

Emerging therapies expand the treatment landscape for coronary artery disease

Announcing a new article publication for Cardiovascular Innovations and Applications. Coronary artery disease (CAD) remains the leading cause of death globally, despite the limited efficacy of current pharmacological therapies.

25 Sep 2026

Screening approved medicines reveals potential treatments for preterm labor

Shajila Siricilla, PhD, Assistant Professor of Pediatrics, and Jennifer Herington, PhD, Associate Professor of Pediatrics, led a team that systematically screened 1,191 FDA-approved drugs and found that several candidates met criteria supporting further evaluation as potential treatments for preterm labor.

23 Sep 2026

New AI tool predicts hydrogen positions to speed up drug discovery

New York University researchers have trained an AI model to learn chemical patterns associated with stability in drug-like molecules and accurately predict where their hydrogen atoms should be positioned.

23 Sep 2026

Marine carbohydrates offer valuable new resources for drug development

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

22 Sep 2026

Researchers identify a rare genetic change linked to neurodevelopmental disorder

Research led by Texas Children's Duncan Neurological Research Institute (Duncan NRI) and Baylor College of Medicine identified a rare genetic change that appears to cause a newly recognized neurodevelopmental disorder.

21 Sep 2026

Researchers create virtual cells to accelerate drug discovery efforts

Mitochondria - tiny structures that convert nutrients into energy - are often depicted as discrete kidney bean-shaped objects.

18 Sep 2026

Nighttime light exposure linked to sleep disruption in people with schizophrenia

Sleep problems are common in people with schizophrenia and can worsen quality of life, psychiatric symptoms, cognition, and daily functioning.

18 Sep 2026

Big Picture Bio founded to identify, design and optimize promising cancer combination therapies

Big Picture Bio Ltd., has been founded to identify, design and optimize promising cancer combination therapies, using a generative world model to understand how tumors, immune cells and surrounding tissue interact across disease sites and patient subgroups.

From Big Picture Bio 18 Sep 2026

Drug Discovery News and Research

Further Reading

Hyponatremia risk varies among individual second-generation antipsychotic drugs

ELRIG and The Protein Society announce keynote speakers for Protein Sciences in Drug Discovery 2026

Carterra advances lab-in-the-loop drug discovery through new scientific collaboration

Scientists discover a novel strategy to unmask cancer cells in high-risk neuroblastoma

Managing misfolded proteins to prevent Parkinson’s disease

BioDuro appoints Greg Makara as Senior Vice President Lead Discovery Chemistry to strengthen early drug discovery capabilities

CN Bio announces expert speaker line-up and scientific program for inaugural Organ-on-a-chip e-Symposium

Dr. GPCR and Eurofins Discovery join forces to advance GPCR drug discovery

Fluorescent sensors could help researchers see diabetes in action

Streamlining CRISPR workflows, from editing to analysis

MolBoolean™ measures free and bound proteins in the same experiment

An AI-identified biomarker can look accurate and still fail its biggest test

Emerging therapies expand the treatment landscape for coronary artery disease

Screening approved medicines reveals potential treatments for preterm labor

New AI tool predicts hydrogen positions to speed up drug discovery

Marine carbohydrates offer valuable new resources for drug development

Researchers identify a rare genetic change linked to neurodevelopmental disorder

Researchers create virtual cells to accelerate drug discovery efforts

Nighttime light exposure linked to sleep disruption in people with schizophrenia

Big Picture Bio founded to identify, design and optimize promising cancer combination therapies

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