Fertilization News and Research

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Polygenic embryo testing raises ethical concerns beyond disease prevention

For more than four decades, in vitro fertilization (IVF) has helped families have children. Scientists estimate that more than 10 million people worldwide have been born through IVF and related assisted reproductive technologies, according to the International Committee for Monitoring Assisted Reproductive Technologies.

31 Mar 2026

Microgravity reduces the ability of sperm to navigate reproductive tracts

Having a baby in space may require a bit more direction, with new Adelaide University research revealing the navigational abilities of sperm are negatively impacted by a lack of gravity.

26 Mar 2026

Fertility treatments linked to small increases in some cancers

Findings indicate small increases in certain cancers linked to assisted reproduction, though overall cancer incidence aligns with the general female population.

13 Mar 2026

Targeted mRNA delivery restores sperm production and fertility in infertile mice

Researchers have found that targeted delivery of messenger RNA (mRNA) can restore sperm production and fertility in genetically infertile male mice.

5 Mar 2026

Repurposed kidney drug finerenone shows promise in treating premature ovarian insufficiency

Premature ovarian insufficiency (POI) is a clinically significant cause of infertility that affects between 1 to 3% of women of childbearing age.

5 Mar 2026

Optically invisible culture dishes improve embryo imaging in IVF

Selecting the healthiest embryo is one of the most important steps in in‑vitro fertilization (IVF), yet it remains one of the most uncertain.

4 Feb 2026

IVF study finds shorter insemination protects embryo availability without harming success

Short-term sperm–oocyte co-incubation during IVF cycles with only one or two retrieved oocytes produced cumulative live birth rates comparable to conventional overnight insemination. It also improved fertilisation metrics and reduced cancellation or no-embryo cycles, suggesting practical laboratory advantages without improving overall live birth probability.

4 Feb 2026

Natural ovulation offers a safer path to IVF success

Researchers compare the effects of natural ovulation and external hormone replacement regimens for preparing the uterus before frozen embryo transfer.

4 Feb 2026

Targeted uterine mRNA treatment boosts fertility outcomes in mice

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine - which designs nanotechnology-based platforms for clinical translation across specialties - developed a strategy for delivering therapeutic messenger RNA (mRNA) to the inner lining of the uterus (endometrium) in mice via modified lipid nanoparticles (LNPs), which are small capsules made of fatty molecules.

22 Jan 2026

Age-related sperm changes at imprint regions linked to autism risk

A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled "Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring."

16 Jan 2026

Can ketogenic diets help PCOS? New analysis points to weight and insulin gains

A systematic review and meta-analysis of 15 studies found that ketogenic diets were associated with short-term reductions in body weight, waist circumference, insulin resistance, and some reproductive hormones in women with polycystic ovary syndrome, primarily among those with overweight or obesity. However, substantial heterogeneity, low certainty of evidence, limited safety reporting, and short follow-up periods mean the clinical effectiveness and long-term sustainability of ketogenic diets in PCOS remain uncertain.

5 Jan 2026

Private equity firms increasingly dominate fertility clinics in the United States

The rise of private equity firms investing in health care facilities across the United States has been exploding in the last decade.

30 Dec 2025

Engineered womb lining model opens a window into embryo implantation

By engineering a system replicating the womb lining with high biological accuracy, researchers at the Babraham Institute and Stanford University have been able to study the implantation of human embryos, opening up this enigmatic process to investigation.

23 Dec 2025

Trump wants Americans to make more babies. Critics say his policies won’t help raise them.

Maddy Olcott plans to start a career once she graduates from college. But the junior at the State University of New York-Purchase College is so far not planning to start a family — even with the Trump administration dangling inducements like thousand-dollar "baby bonuses" or cheaper infertility drugs.

3 Dec 2025

WHO releases first-ever global guideline for prevention, diagnosis and treatment of infertility

The World Health Organization (WHO) today called on countries to make fertility care safer, fairer and more affordable for all in its first-ever global guideline for the prevention, diagnosis and treatment of infertility.

29 Nov 2025

Study uncovers role of mechanical forces in human gastrulation

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear.

22 Nov 2025

Maternal age drives embryo arrest independently of chromosomal errors

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 10, 2025, titled "Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos."

20 Nov 2025

Study finds increased rates of DNA mutations in mice pups conceived with IVF

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive technologies suggests.

17 Nov 2025

KFF Health News' 'What the Health?': Nutrition programs face their own shutdown

Health programs are feeling the pinch of the ongoing government shutdown. Funding for the Supplemental Nutrition Assistance Program, or SNAP, and the food program for women, infants, and children, WIC, is likely to run out in November, and cuts at the Centers for Disease Control and Prevention are keeping the agency from carrying out some of its primary public health functions.

23 Oct 2025

Study: Common test to assess viability of IVF embryos may be flawed

A test deployed in many fertility clinics to assess the viability of embryos for use in IVF is likely to overestimate the number of embryos with abnormalities, suggests a study published today.

23 Oct 2025