Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

From turmeric to fenugreek, scientists examine nature’s potential role in diabetes care

A narrative review examined how curcumin, honey, culinary spices, and traditional remedies may influence oxidative stress, inflammation, mitochondrial function, and insulin signaling in diabetes. Although experimental research and some clinical trials suggest potential metabolic benefits, the authors emphasize that larger, well-controlled studies are needed to establish their effectiveness and safety alongside conventional treatments.

14 Oct 2026

Doctors avoided two common words when talking about weight with patients

Researchers analyzed 123 recorded primary care consultations involving adults with type 2 diabetes and elevated BMI, finding that weight was discussed in just 39% of visits. Clinicians avoided potentially stigmatizing terms such as "overweight" and "obesity," while weight-related conversations occurred more frequently among patients taking GLP-1 receptor agonists.

13 Oct 2026

ACLM launches resources to meet new medical nutrition requirements

The American College of Lifestyle Medicine (ACLM) has launched two resources to help medical schools meet new federal nutrition requirements and to support practicing physicians seeking education relevant to state-level nutrition education requirements.

13 Oct 2026

Women with polyendocrine metabolic ovarian syndrome more likely to have Alzheimer's and dementia

Alzheimer's disease and dementia may be more common in women with polyendocrine metabolic ovarian syndrome (PMOS), formerly known as polycystic ovary syndrome (PCOS), according to a review of existing evidence published in the Journal of the Endocrine Society.

13 Oct 2026

Nearly 400,000 adults, six body measurements, and a surprising result for heart attack risk

A UK Biobank study involving 395,831 adults found that a higher body roundness index (BRI) was associated with an increased risk of myocardial infarction over a median follow-up of 13.3 years. BRI showed slightly better predictive performance than BMI and four other anthropometric measures, although the improvements were modest and require independent validation before clinical adoption.

13 Oct 2026

Three months of yoga before surgery revealed a surprising difference in stress hormones

In a non-randomized study of 40 adults with severe obesity awaiting bariatric surgery, researchers found significantly lower plasma noradrenaline levels in yoga participants than in controls after adjusting for baseline measurements. The researchers detected no significant DNA methylation changes in three inflammatory genes and found no clear psychological or metabolic benefits.

12 Oct 2026

Nutritionally similar meals might not affect your body the same way

Ultra-processed foods trigger distinct metabolic and brain responses, influencing insulin release and nutrient processing despite similar nutritional content.

8 Oct 2026

Does extra protein protect aging muscle during fasting?

A randomized trial found that alternate-day fasting reduced weight in older men, while added protein and leucine did not prevent lean mass loss.

7 Oct 2026

Long-term "Food Is Medicine" program improves cardiometabolic health in adults

Providing people with nutritious foods can improve the management of chronic metabolic diseases such as type 2 diabetes and hypertension.

5 Oct 2026

Tirzepatide cuts fat mass by 35% while preserving skeletal muscle

Tirzepatide cuts body fat while preserving skeletal muscle in real-world study

2 Oct 2026

CBL-514 injection reduces visceral and subcutaneous fat in trials

Details of a new injection that targets fat cells will be released at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

1 Oct 2026

Early-onset type 2 diabetes trial demonstrates significant 24-week fat loss

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Regional Health Americas journal shows that in people who have developed early onset type 2 diabetes (EOT2D) (aged under 45 years), around half these T2D cases can be reversed with a low-energy diet combined with a structured exercise program.

1 Oct 2026

$5.7 million NIH grant supports research on why lean people develop insulin resistance

A Wayne State University research team was awarded a $5.7 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health focused on discovering the biological mechanisms that may help explain why some lean people develop insulin resistance while some people with obesity remain sensitive to insulin.

29 Sep 2026

Exercise may reshape your gut microbiome to support recovery

Research reveals how exercise alters gut microbes, influencing recovery and proposing 'intestinal rehabilitation' for those with limited exercise capacity.

29 Sep 2026

Can’t stop thinking about food? You’re far from alone

Investigating 'food noise', this study reveals its association with diet quality and mental health, emphasizing demographic influences and eating behaviors.

29 Sep 2026

Exam stress significantly raises blood sugar levels in medical students

Exam stress is associated with significant increases in blood sugar levels in medical students both during exams and the days leading up to them, according to new research being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

27 Sep 2026

Gut bacteria signature may predict type 2 diabetes risk

Changes in the composition of bacteria in the gut could provide early warning of type 2 diabetes (T2D), new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) has found.

27 Sep 2026

A chemical used in BPA-free products may have a connection to diabetes control

In adults with type 2 diabetes receiving oral glucose-lowering therapy, higher plasma BPS concentrations were associated with higher HbA1c after accounting for demographic factors, medication adherence, and diet, whereas BPA was not associated with HbA1c. The BPS association was modest and no longer statistically significant after further adjustment for BPA, BMI, and physical fitness, supporting the need for larger studies to determine whether reducing exposure could improve glycemic control.

23 Sep 2026

Higher ultra-processed food intake linked to multiple health risks

A higher ultra processed food (UPF) intake is linked to a heightened risk of several major chronic health issues, such as digestive diseases, high blood pressure, and metabolic syndrome/diabetes, as well as death, finds a pooled data analysis of the available evidence, published in the open access journal Family Medicine and Community Health.

22 Sep 2026

Cancer incidence rises faster among people with type 2 diabetes

A nationwide study being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) has found that people with type 2 diabetes (T2D) have a higher risk of developing cancer, with cancer incidence rising more among people with T2D than those without diabetes over the past 25 years, largely driven by obesity-related cancers.

22 Sep 2026