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AI system controls brain circuits during social behavior

A male fruit fly in a laboratory chamber extends his wings and vibrates them to produce his species' version of a love song.

12 Feb 2026

Molecular signature of sleeping nociceptors offers new pain targets

Researchers from the Centre for Addiction and Mental Health (CAMH) and the Institute of Neurophysiology at Uniklinik RWTH Aachen in Germany have deciphered the molecular signature of so-called sleeping nociceptors-a type of pain-sensing nerve cell that normally remains quiet and does not respond to touch or pressure, but can become overactive and drive chronic pain.

4 Feb 2026

New research identifies faulty TRPM3 ion channel in ME/CFS immune cells

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), providing long-awaited validation for hundreds of thousands of Australians living with the debilitating illness.

13 Jan 2026

Scientists identify a molecular switch that controls water flow in the gut

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in the U.S. each year, yet scientists have not fully understood what regulates intestinal fluid balance.

9 Jan 2026

Research highlights a potential therapeutic strategy for vascular dementia

A possible new treatment for impaired brain blood flow and related dementias is on the horizon.

22 Dec 2025

Skin and internal organs sense cold through different molecular pathways

A research team led by Félix Viana, co-director of the Sensory Transduction and Nociception laboratory at the Institute for Neurosciences (IN), a joint research centre of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has demonstrated that the body uses different molecular mechanisms to detect cold in the skin and in internal organs.

19 Dec 2025

New research highlights varied cold perception across body tissues

Universidad Miguel Hernández de Elche A research team led by Félix Viana, co-director of the Sensory Transduction and Nociception laboratory at the Institute for Neurosciences (IN), a joint research center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has demonstrated that the body uses different molecular mechanisms to detect cold in the skin and in internal organs.

18 Dec 2025

SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.

12 Dec 2025

Study shines light on how P2X4 receptor can be inhibited

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited.

5 Dec 2025

TRPM1 loss drives rhythmic activity across retinal diseases

Rhythmic electrical activity in the retina (known as pathological oscillations) has been observed in several eye diseases, including congenital stationary night blindness (CSNB) and retinitis pigmentosa (RP).

18 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

New NIH grants fuel research in oral cancer treatment and pain relief

Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have been awarded three multi-year grants totaling $6 million from the National Institutes of Health to address treatment and pain management for oral cancer.

7 Nov 2025

Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects

Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, developed an innovative strategy to construct a series of biodegradable cesium nanosalts.

4 Nov 2025

Researchers visualize how brain network development is altered in rare childhood disorder

Researchers at the VIB-UAntwerp Center for Molecular Neurology have visualized how brain network development is altered in a model of KCNQ2-related developmental and epileptic encephalopathy, a rare childhood brain disorder.

31 Oct 2025

Chiba University study clarifies molecular mechanism driving keloid's unpredictable growth

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic concern; they often cause distressing symptoms such as chronic pain, itching, and restricted movement.

9 Oct 2025

Digital twin of lung cancer cell offers new insights into tumor growth and treatment

An enhanced computer model is now helping to provide fresh insights into cancer-cell growth and how it can be stopped. The digital cell model represents another step towards individualized cancer treatment.

18 Sep 2025

Axxam and B'SYS partner to expand access to validated ion channel cell lines for high-throughput electrophysiology

Axxam S.p.A., a premier provider of integrated early drug discovery services, and B'SYS GmbH, a specialist in ion channel biology, are pleased to announce a strategic collaboration focused on enabling access to validated ion channel cell lines for hit and lead identification through high-throughput electrophysiological screening.

From Axxam S.p.A 8 Sep 2025