Myelin News and Research

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Myelin is the fatty substance that covers and protects nerves.

Low-dose lithium may protect brain networks in early Alzheimer’s disease

This perspective examines whether restoring physiological lithium levels could help protect cognition in early Alzheimer’s disease. It proposes that lithium may support cholinergic signaling and brain connectivity, but emphasizes that rigorous, safety-monitored clinical trials are needed.

21 Jul 2026

Damaged myelin alters sleep brain rhythms in neurological diseases

Scientists have discovered how damage to the myelin sheath – the insulating layer around nerve fibres – affects brain activity during sleep.

9 Jul 2026

Study reveals how glial cells regulate brain injury and recovery

Traumatic brain injury (TBI) affects millions of people worldwide every year and remains a major cause of long-term disability, cognitive decline, and neurological complications.

8 Jul 2026

New gene therapy strategy uses the brain's own glymphatic transport system for drug delivery

A new study describes a gene therapy strategy that uses the brain's own glymphatic transport system to distribute engineered viral vectors throughout the brain.

8 Jul 2026

Study uncovers genetic clues behind sex differences in Parkinson's disease

New research presented today (Wednesday) at the Federation of European Neuroscience Societies (FENS) Forum 2026 has discovered some of the genetic changes in brain cells that may help to explain why more men than women develop Parkinson's disease.

7 Jul 2026

Rare pelvic schwannoma removed with nerve-sparing laparoscopic surgery

Through interdepartmental collaboration, a young woman's quality of life and ability to walk were restored following the laparoscopic removal of a rare, benign tumor of neurological origin in the lesser pelvis, known as a schwannoma (also called a neurinoma).

26 Jun 2026

Pheno Therapeutics granted FDA IND clearance for lead multiple sclerosis therapeutic candidate PTD802

Pheno Therapeutics Limited. (Pheno), a clinical stage biotechnology company focused on the discovery and development of small molecule therapeutics for the treatment of neurological diseases, today announced that the US Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for PTD802, the Company's lead therapeutic candidate.

From Pheno Therapeutics 22 Jun 2026

The cerebellum may help aging brains stay sharper

A large MRI study of more than 47,000 adults found that cerebellar aging is uneven, with posterior association regions and some motor-related areas showing steeper age-related changes. Larger cerebellar volumes were linked to better cognitive performance, supporting a threshold-reserve model in which the cerebellum may help sustain cognition before Alzheimer’s pathology becomes widespread.

11 Jun 2026

The best foods for brain health may change as you age

Investigating brain foods, this review highlights dietary influences on cognition and neurodevelopment, while addressing significant gaps in current research.

3 Jun 2026

New reference models track lifespan changes in brain wiring

Researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have created one of the largest reference models ever developed for the human brain, using diffusion MRI scans from more than 54,000 people to chart how the brain's communication pathways develop, mature, and decline across the lifespan.

2 Jun 2026

Higher-dose ocrelizumab depletes more B cells but does not slow MS progression

Higher-dose ocrelizumab produced greater peripheral B-cell depletion than the approved 600 mg regimen in two phase 3b trials of relapsing and primary progressive multiple sclerosis. However, the higher doses did not significantly delay disability progression, supporting the 600 mg dose as the current standard regimen with a favorable benefit-risk profile.

31 May 2026

New study shows how exercise hormone reduces multiple sclerosis symptoms

A new study offers clues as to why exercise can improve neurological symptoms in people with multiple sclerosis (MS).

21 May 2026

Preclinical models map genetic changes behind multiple sclerosis nerve damage

More than 1 million people across the United States live with multiple sclerosis (MS), a disease that affects the brain, optic nerves and spine.

18 May 2026

Glucose acts as a metabolic signal for myelin development

Researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have uncovered a surprising link between low brain sugar levels and the development of myelin - the protective coating that allows nerve cells to communicate rapidly and efficiently.

30 Apr 2026

Pinecone-inspired conduit enables suture-free repair of nerve injuries

As the authors detail, PNI is a prevalent neurological condition that often causes permanent sensory and motor dysfunction, severely impairing patient's quality of life.

21 Apr 2026

Enriched environments improve stroke recovery and reduce brain inflammation

Stroke is one of the leading causes of death worldwide. Its recovery is often challenging as most of the stroke survivors remain chronically disabled, with motor deficits affecting a significant percentage of patients.

11 Apr 2026

DNA damage in gray matter neurons linked to MS progression

For decades, multiple sclerosis research has focused on myelin, the insulation around the brain's wiring. Scientists paid less attention to another loss that was happening in parallel: neurons in the cortex, the seat of higher thinking and cognition, were quietly dying.

1 Apr 2026