Enzyme News and Research

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Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal disease.

30 Dec 2025

Scientists capture real-time action of antiviral drugs on herpes

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

30 Dec 2025

Aptamer Group and Alphazyme execute licensing agreement for synthetic aptamer-based enzyme modulation in hot-start PCR

Aptamer Group plc, a developer of synthetic oligonucleotide-based binding reagents for life sciences applications, and Alphazyme LLC (Alphazyme), a Maravai LifeSciences company specializing in enzymes for molecular biology, have executed a licensing agreement for a proprietary Optimer® binder developed for hot-start polymerase chain reaction (PCR) applications.

From Aptamer Group 24 Dec 2025

Discovery of fat-regulating enzyme points to a new obesity therapy

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD).

23 Dec 2025

Fatty diets reprogram hepatocytes and increase liver cancer risk

One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.

22 Dec 2025

ARB drugs lead to better blood pressure treatment adherence

Patients who start their blood pressure treatment with ARB drugs continue with the same medicine to a greater extent than patients who start out with other drugs.

22 Dec 2025

New insights into how a molecular gatekeeper controls early protein modification

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have now discovered that this complex also contributes a crucial function in ensuring that our DNA is properly processed and “packaged”.

19 Dec 2025

Researchers point to mitochondria as a missing link between mental health and brain function

A stressful year leads to anxiety. Lasting isolation gives way to depression. An old trauma nags until it becomes paralyzing.

18 Dec 2025

RNAConnect launches the UltraMarathonRT Direct RNA‑Seq Kit to advance nanopore-based native RNA sequencing

RNAConnect, a life science company providing next generation tools to the RNA community, today announced the commercial availability of the UltraMarathonRT® Direct RNA‑Seq (uMRT DRS) Kit, a native‑RNA library preparation solution for Oxford Nanopore Technologies® direct RNA sequencing (SQK-RNA004).

From RNAConnect 17 Dec 2025

Baloxavir reduces flu-related hospitalizations more than oseltamivir

A study reveals baloxavir outperforms oseltamivir in reducing hospitalization rates for influenza, highlighting its clinical advantages in outpatient settings.

17 Dec 2025

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance demonstrated in studies in mice that could lay the groundwork for safer, more precise treatments for cancer and other diseases.

16 Dec 2025

Researchers uncover how Bartonella causes deadly Oroya fever

The so-called "Oroya fever" is an extremely severe infectious disease, yet it is classified among the so-called neglected tropical diseases.

15 Dec 2025

New insights into alcohol-related DNA damage and cancer risk

Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA.

15 Dec 2025

Single-pill combination medications may simplify treatment for adults with high blood pressure

Taking one pill that combines two or more blood pressure medications may help adults with high blood pressure (also known as hypertension) lower their blood pressure level faster and more effectively than taking multiple medications separately, and it may also reduce the risk of heart attack and stroke, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

15 Dec 2025

Bioluminescent tool illuminates single-cell activity in living brains

A decade ago, a group of scientists had the literally brilliant idea to use bioluminescent light to visualize brain activity.

12 Dec 2025

Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name - cell migration inducing and hyaluronan-binding protein, or CEMIP - is associated with disorders ranging from multiple sclerosis to stroke to neurodegenerative conditions like Alzheimer's disease.

11 Dec 2025

Researchers discover the enzyme responsible for chromothripsis in cancer

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.

11 Dec 2025

Psoriasis caused by changes in the fat metabolism of skin cells

A research team led by Erwin F. Wagner from the Medical University of Vienna has discovered a previously unknown molecular mechanism that contributes to the development of psoriasis - and at the same time represents a potential biomarker for a new treatment concept.

11 Dec 2025

Pirtobrutinib shows superior outcomes compared to common first-line combination treatment for CLL/SLL

In a new trial, the Bruton tyrosine kinase (BTK) inhibitor pirtobrutinib increased the rate of survival without disease progression and was well tolerated with a more favorable safety profile when compared with bendamustine plus rituximab (BR) in patients with previously untreated chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).

10 Dec 2025

Enzyme News and Research

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Scientists capture real-time action of antiviral drugs on herpes

Aptamer Group and Alphazyme execute licensing agreement for synthetic aptamer-based enzyme modulation in hot-start PCR

Discovery of fat-regulating enzyme points to a new obesity therapy

Fatty diets reprogram hepatocytes and increase liver cancer risk

ARB drugs lead to better blood pressure treatment adherence

New insights into how a molecular gatekeeper controls early protein modification

Researchers point to mitochondria as a missing link between mental health and brain function

RNAConnect launches the UltraMarathonRT Direct RNA‑Seq Kit to advance nanopore-based native RNA sequencing

Baloxavir reduces flu-related hospitalizations more than oseltamivir

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Researchers uncover how Bartonella causes deadly Oroya fever

New insights into alcohol-related DNA damage and cancer risk

Single-pill combination medications may simplify treatment for adults with high blood pressure

Bioluminescent tool illuminates single-cell activity in living brains

Researchers identify enzyme linked to myelin damage and neurodegenerative conditions

Researchers discover the enzyme responsible for chromothripsis in cancer

Psoriasis caused by changes in the fat metabolism of skin cells

Pirtobrutinib shows superior outcomes compared to common first-line combination treatment for CLL/SLL

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo