Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

Aligning your body clock may protect your heart and metabolism, says AHA

A new American Heart Association scientific statement highlights how maintaining circadian health through regular sleep, light exposure, meal timing, and exercise may reduce cardiometabolic disease risk. Disrupting these daily rhythms can impair glucose regulation, blood pressure, and cardiovascular function.

29 Oct 2025

Retaining gonad function could be a potent strategy to fight late-life frailty

Frailty threatens older individuals because it increases their vulnerability to detrimental health outcomes, such as falling, longer hospitalization, or even shortened life expectancy.

29 Oct 2025

AI indelibly transforms solid tumor drug development

Artificial intelligence (AI) is fundamentally reshaping the landscape of solid tumor (ST) drug development.

29 Oct 2025

Flavanol-rich foods offer vascular protection during extended sitting

New research from the University of Birmingham shows that eating flavanol-rich foods-like tea, berries, apples, and cocoa-can protect vascular health in men from the harmful effects of prolonged sitting.

29 Oct 2025

Four distinct subgroups of PCOS open up for more tailored treatments

Four distinct subgroups of polycystic ovary syndrome (PCOS) have been identified in an international study published in Nature Medicine by researchers from Karolinska Institutet, among others.

29 Oct 2025

New mechanism behind potentially fatal type of epilepsy identified

A team led by the UAB Institut de Neurociències (INc-UAB) has for the first time identified the mechanism behind a potentially fatal type of epilepsy, a symptom of mitochondrial diseases.

27 Oct 2025

Mitochondria and lysosomes work together to control regulatory T cell activation

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

24 Oct 2025

Study unravels the genetic shield against winter vomiting disease

Winter vomiting disease is caused by the Norovirus, which is most virulent during the colder half of the year.

24 Oct 2025

Fitness amongst young adults strongly linked to socioeconomic development and gender equality

Fitness amongst young adults varies widely from one country to another, and is strongly associated with both socioeconomic development and gender equality, a new study from Karolinska Institutet published in the Journal of Sport and Health Science reports.

23 Oct 2025

Research opens new avenues for treating asthma and other inflammatory diseases

For decades, scientists have thought they understood the biochemical machinery that causes asthma-inflammation in the lungs that constricts airways and makes it hard to breathe.

23 Oct 2025

New York Regional Diabetes Research Center established with $10.8 million NIH grant

Albert Einstein College of Medicine has received a five-year, $10.8 million grant from the National Institutes of Health (NIH) to create the New York Regional Diabetes Research Center (NYR-DRC), a newly expanded multi-institutional center co-led with the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine.

23 Oct 2025

Physically fit individuals may better cope with dehydration stress

Individuals who are physically fit may be better equipped to handle the negative effects of dehydration, according to research from the University of California, Riverside. In a study using selectively bred "high-runner" mice, the scientists found that fitter animals increased their voluntary running activity when deprived of water - a finding that could have implications for human performance and health under environmental stress.

23 Oct 2025

Study sheds light on how aging unfolds in pets and humans

Scientists have long sought measurable signs in the body, called biomarkers, that reliably reveal our biological age or predict future health issues.

22 Oct 2025

Researchers gain new insights into aging based on studies in dogs

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.

22 Oct 2025

E2F2 protein identified as potential therapeutic target to prevent metabolic fatty liver disease progression

An international collaborative study has identified the E2F2 protein as a potential new therapeutic target to prevent metabolic fatty liver disease from progressing towards more serious conditions, such as cirrhosis or liver cancer.

22 Oct 2025

Scientists question the safety and efficacy of the diet for metabolic health

A study published in Science Advances by University of Utah Health researchers sheds light on the long-term effects of the ketogenic diet, raising important questions about its safety and efficacy for improving metabolic health.

22 Oct 2025

Cyclana Bio raises £5M to advance drug discovery for endometriosis

Cyclana Bio, a biotechnology company pioneering tissue-level approaches to women's health, today announced the close of a £5M pre-seed funding round, co-led by NfX and Eka VC, and including Cocoa VC, Wilbe, and Angel investors.

21 Oct 2025

Researchers discover how a brain circuit allows eating despite anxiety

How do mammals manage to eat in situations that cause anxiety, step into exposed spaces, or slow down when anxiety drives them to keep moving? A new study pinpoints a leptin-sensitive circuit in the lateral hypothalamus that helps to overcome anxiety to perform essential behaviors such as exploring, feeding, and limiting maladaptive hyperactivity.

21 Oct 2025

Can fitness apps and wearables make children healthier? This study says yes - partly

Digital health tools such as apps, wearables, and web platforms can modestly improve children’s physical activity, diet, and weight outcomes. Shorter programs boost activity, while longer ones better support weight management, though effects on sleep and sedentary time remain unclear.

20 Oct 2025

$Yogurt’s impact on bone health falls short of fracture protection, review finds$

Yogurt’s impact on bone health falls short of fracture protection, review finds

This systematic review and meta-analysis found that while yogurt consumption shows a modest positive association with bone health markers, its effect on bone mineral density and fracture prevention in adults is clinically negligible. Current evidence is based solely on observational studies, with low certainty and limited characterization of yogurt products.

19 Oct 2025