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Smartphone data can reveal early dementia risks during real-world navigation

Researchers found that smartphone data from a wayfinding task can reveal cognitive decline patterns in older adults, especially those with subjective cognitive decline (SCD).

8 Oct 2024

Global analysis reveals disparities in access to new cancer drugs

Despite considerable progress in the discovery and development of new cancer drugs, there are significant disparities in both the availability and timeliness of these medicines worldwide, with poorer countries missing out, suggests a global analysis of new drug launches between 1990 and 2022, published in the open access journal BMJ Global Health.

8 Oct 2024

Modified bloodroot compound shows promise against multidrug-resistant tuberculosis

A modified compound taken from bloodroot, a wildflower native to North America, effectively fights multidrug-resistant tuberculosis (TB) bacteria in the test tube, according to a new study.

8 Oct 2024

New triple-targeting pharmacological tool developed for cancer treatment

A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different therapeutic target within the cell.

8 Oct 2024

Revolutionizing drug discovery with SmartCADD

Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects.

8 Oct 2024

Deciphering the Mysteries of the Human Microbiome

The Microsetta Initiative studies human microbiomes, analyzing diverse data to reveal links between microbes, diet, and health for improved public health.

8 Oct 2024

What’s new and what to watch for in the upcoming ACA open enrollment period

It's that time of year again: In most states, the Affordable Care Act's annual open enrollment season for health plans begins Nov. 1 and lasts through Jan. 15.

8 Oct 2024

Environmental factors significantly impact gene expression through epigenetic modifications

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment. The review article "Epigenetics and Environmental Health" provides an in-depth analysis of how epigenetic modifications can influence the onset and progression of various diseases, particularly cancer and cardiovascular diseases.

8 Oct 2024

Unexpected benzene levels in popular acne and rosacea products

Investigators have determined that a substantial portion of topical benzoyl peroxide (BPO) acne and rosacea treatments currently on the market are unstable and contain unacceptably high levels of benzene, a known human carcinogen.

7 Oct 2024

GLP-1 drugs protect brain health by improving neurovascular function and reducing inflammation

Research highlights how GLP-1 receptor agonists may improve brain health by targeting the neurovascular unit, linking metabolic health to cognitive function. It suggests potential therapies for neurodegenerative diseases like Alzheimer's.

7 Oct 2024

Researchers discover effective treatment strategy for lethal glioblastoma

Glioblastoma (GBM) is the most lethal brain tumor, with a median survival rate of merely 12-16 months after diagnosis. Despite surgical, radiation and chemotherapy treatments, the two-year survival rate for GBM patients is less than 10%.

7 Oct 2024

New insights on 5-fluorouracil's mechanism in different cancers

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

7 Oct 2024

Early blood test can predict treatment response and survival prospects in metastatic prostate cancer

A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest.

7 Oct 2024

Epigenetic testing opens new doors for multiple myeloma treatment

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population.

7 Oct 2024

New research highlights the impact of stigma on health equity

A new article published in Nature Reviews Disease Primers underscores the profound role that stigma can play in health care -- and how addressing stigma-related barriers can significantly improve health outcomes for individuals and communities around the world.

7 Oct 2024

Study reveals sponsorship bias in psychiatric drug trials

Psychiatric drugs are reported to be about 50% more effective in clinical trials funded by the drug's manufacturer than when trials of the same drug are sponsored by other groups, new research shows.

7 Oct 2024

New deep-learning framework identifies non-addictive pain relief options

An estimated one in five Americans live with chronic pain and current treatment options leave much to be desired.

7 Oct 2024

Study reveals bias in substance use screening for injured adolescents

Injured adolescents from marginalized groups treated at pediatric trauma centers are more likely to be tested for drugs and alcohol than white adolescents, even when accounting for injury severity, a study led by researchers at UCLA and Children's Hospital Los Angeles suggests.

4 Oct 2024

Women who inject drugs are vulnerable to endocarditis, study shows

People who inject drugs are dying at an alarming rate from endocarditis, a serious but treatable heart-valve infection.

4 Oct 2024

Exploring the venomous potential of marine crustaceans for drug development

Many animals use venoms for self-defense or hunting. The components of such venom, known as toxins, interfere with various physiological processes - which is also the reason why they are so interesting for the development of new pharmacological agents.

4 Oct 2024