Aging News and Research

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Mitochondrial protein structure activates cell's integrated stress response

Often referred to as the "powerhouses of the cell," mitochondria are well known for their role as energy suppliers, but these organelles are also critical for maintaining our overall health.

8 Aug 2023

Impact of age-related alterations in lipid metabolism on general health

Scientists provide a detailed overview on age-related alterations in lipid metabolism and its association with age-related chronic diseases.

8 Aug 2023

SLU research finds link between anxiety disorders, benzodiazepine exposure and dementia in seniors

Research from Saint Louis University School of Medicine finds that among patients 65 and older, a diagnosis of anxiety was significantly associated with an increased risk of dementia diagnosis, and benzodiazepine exposure was associated with a 28% increased risk of dementia.

7 Aug 2023

Air pollution linked to increased use of community mental health services in people with dementia

Exposure to relatively high levels of air pollution is linked to increased use of community mental health services by people with dementia, finds a large long term study focusing on a large area of London with heavy traffic and published in the open access journal BMJ Mental Health.

7 Aug 2023

Air pollution linked to increased risk of non-lung cancer in older adults

Chronic exposure to fine particulate air pollutants (PM2.5) and nitrogen dioxide (NO2) may increase non-lung cancer risk in older adults, according to a study led by Harvard T.H. Chan School of Public Health.

7 Aug 2023

Similarities in gene expression between post-mortem and living human brains

Researchers compare human prefrontal cortex gene expression between living and post-mortem samples.

7 Aug 2023

How does the circulating proteome influence brain health?

Researchers investigate the association between the circulating proteome and brain health.

7 Aug 2023

Exploring human aging via elephant research

Indiana University researcher Daniella Chusyd is studying human aging in an unlikely way: through elephants.

4 Aug 2023

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Neurologist Beau Ances, MD, PhD, talks with his patient, Adam Kloppenberg, who has Down syndrome, at Washington University School of Medicine in St. Louis. People with Down syndrome are at very high risk of developing Alzheimer's disease. Ances is involved in a project led by Jason Hassenstab, PhD, an associate professor of neurology, to develop tools to measure cognitive function in people with Down syndrome-associated Alzheimer's disease.

3 Aug 2023

Researchers discover how aging can lead to chronic metabolic disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

3 Aug 2023

Simple interview technique could help detect early signs of dementia

Research at the Florida State University College of Medicine has identified a potential low-cost method for predicting if a person is at risk of developing dementia.

3 Aug 2023

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors' importance in depression and potential as therapeutic targets.

3 Aug 2023

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has demonstrated that it can predict the outcome of Phase II to Phase III clinical trial success using its proprietary transformer-based AI clinical trial prediction tool called inClinico with a high degree of accuracy.

3 Aug 2023

COST catalyzes collaborative research in transcriptomics for cardiovascular disease

The Action has not only catalyzed research in this area by bringing together almost 300 participants from across Europe and beyond, but it also catalyzed the careers of younger researchers and launched a Horizon 2020 project: COVIRNA.

2 Aug 2023

Moderna vaccine linked to lower risk of adverse events in older adults

While mRNA vaccines against COVID-19 have been found to be safe and effective for the general population, in-depth evidence about safety and effectiveness for older adults and individuals with chronic health conditions is more limited.

2 Aug 2023

Infertility may be a risk factor for some menopause symptoms, study suggests

Not all women experience menopause the same way. The severity of menopause symptoms is influenced by a multitude of behavioral, biological, social, psychological, and demographic factors.

2 Aug 2023

Insilico Medicine uses AI to discover novel SIK2 inhibitors

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

2 Aug 2023

Childhood trauma can lead to physical and cognitive impairments in old age

Adverse childhood experiences have impacts deep into old age, especially for those who experienced violence, and include both physical and cognitive impairments.

2 Aug 2023

The number of deaths attributable to second hand smoke exposure has increased between 1990 and 2019

Researchers estimated the prevalence of and assessed trends in exposure to second-hand smoke (SHS)

2 Aug 2023

Aging News and Research

Mitochondrial protein structure activates cell's integrated stress response

Impact of age-related alterations in lipid metabolism on general health

SLU research finds link between anxiety disorders, benzodiazepine exposure and dementia in seniors

Air pollution linked to increased use of community mental health services in people with dementia

Air pollution linked to increased risk of non-lung cancer in older adults

Similarities in gene expression between post-mortem and living human brains

How does the circulating proteome influence brain health?

Exploring human aging via elephant research

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Researchers discover how aging can lead to chronic metabolic disorders

Simple interview technique could help detect early signs of dementia

GABA-modulating treatments could help tackle cognitive, affective symptoms associated with depression

Insilico Medicine's new AI tool shows promise in predicting clinical trial outcomes

COST catalyzes collaborative research in transcriptomics for cardiovascular disease

Moderna vaccine linked to lower risk of adverse events in older adults

Infertility may be a risk factor for some menopause symptoms, study suggests

Insilico Medicine uses AI to discover novel SIK2 inhibitors

Childhood trauma can lead to physical and cognitive impairments in old age

The number of deaths attributable to second hand smoke exposure has increased between 1990 and 2019

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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