Clinical Trial News and Research

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Clinically relevant biomarker strategies in drug development

In this interview, NewsMedical speaks with Dr. Justin Devine and Dr. Nicholas Woudberg about biomarkers, their importance for drug development as well as the potential they have when it comes to machine learning.

From Synexa Life Sciences 9 Jan 2023

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Newly published research from the University of Cincinnati finds that people with latent tuberculosis infection (LTBI) have more inflammation and could be at a higher risk for cardiovascular disease.

6 Jan 2023

Low-cost intervention can make a difference to America's deadly overdose epidemic

There are no simple solutions to America's deadly overdose epidemic, which costs 100,000 lives each year and is erasing gains in life expectancy.

6 Jan 2023

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Talking, smiling, eating together – these are all social activities that are inherent to the human experience. But for some head and neck cancer survivors, they are dreaded tasks.

6 Jan 2023

Cerba Research is officially a member of Hong Kong Bio-Med Innotech Association (HKBMIA)

Cerba Research announces membership of HKBMIA to act as an advisor on speciality testing and routine clinical trials testing to advance research and health while supporting Asia pacific healthcare companies develop new therapeutics.

From Cerba Research 6 Jan 2023

Researchers take an important step forward in treating combat-related post-traumatic stress disorder

Study findings out today in JAMA Network Open show an important step forward in treating the psychological injuries of war.

5 Jan 2023

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells in and around a tumor, called tumor-infiltrating lymphocytes (TILs), in predicting whether HER2-positive breast cancer responds to treatment.

5 Jan 2023

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Insilico Medicine, a clinical stage, end-to-end artificial intelligence (AI)-driven drug discovery company, held the launch ceremony for Life Star – a 6th generation Intelligent Robotics Drug Discovery Laboratory – in Suzhou BioBAY Industrial Park on Dec. 29.

5 Jan 2023

Acupuncture could be a safe and feasible management option for IBS-D

Researchers preliminarily evaluated the practicality of utilizing the United States (US) Food and Drug Administration (FDA)-advocated endpoints to assess the effectiveness of acupuncture in IBS-D (irritable bowel syndrome with diarrhea) management.

5 Jan 2023

Study assesses microbiome of male genital mucosa

A new study in the journal Microorganisms aimed to identify and analyze studies on the composition of the microbial community on different parts of the healthy and diseased male genital mucosa.

4 Jan 2023

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.

4 Jan 2023

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Newly published research out of the University of Cincinnati and the University of California-Davis shows that direct oral anticoagulant (DOAC) drugs are more effective and are more cost-effective than low molecular weight heparin for treating cancer-associated thrombosis.

4 Jan 2023

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

Researchers conducted a literature review to determine whether platelet-rich plasma therapy could help slow disease progression through lung regeneration in patients with chronic respiratory disease.

4 Jan 2023

RQM+ Launches Clinical Trial Services

RQM+ today announced the launch of its clinical trial services division to complete its full complement of MedTech contract research organization (CRO) services.

From RQM+ 4 Jan 2023

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with poor prognosis and limited treatment options.

3 Jan 2023

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

A clinical trial led by the National Cancer Institute (NCI), part of the National Institutes of Health, has resulted in the first approval of a treatment for advanced alveolar soft part sarcoma (ASPS).

28 Dec 2022

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer's disease neurodegeneration in a blood sample. A study on their results was published today in Brain.

28 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Study compares two non-invasive interventions for spine pain on disability and health care spending

Pain in the back or the neck is extremely common and accounts for more healthcare spending than any other health condition.

23 Dec 2022

Clinical Trial News and Research

Clinically relevant biomarker strategies in drug development

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Low-cost intervention can make a difference to America's deadly overdose epidemic

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Cerba Research is officially a member of Hong Kong Bio-Med Innotech Association (HKBMIA)

Researchers take an important step forward in treating combat-related post-traumatic stress disorder

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Acupuncture could be a safe and feasible management option for IBS-D

Study assesses microbiome of male genital mucosa

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Is platelet-rich plasma therapy beneficial in treating chronic respiratory disease?

RQM+ Launches Clinical Trial Services

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Study compares two non-invasive interventions for spine pain on disability and health care spending

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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