Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Astrocytes protect neurons from damaging side effects of overactivity

Astrocytes are overtaxed neurons' pit crew. The brain cells collect damaged lipids secreted by hyperactive neurons, then recycle those toxic molecules into energy, researchers at the Howard Hughes Medical Institute's Janelia Research Campus report May 23, 2019, in the journal Cell.

3 Jun 2019

Alzheimer's Drug Discovery Foundation announces first round of awards of Diagnostics Accelerator initiative

The Alzheimer's Drug Discovery Foundation announced today the first group of researchers who will receive funding through its Diagnostics Accelerator, a new research program that aims to fast-track the development of diagnostic tools and biomarkers for Alzheimer's disease and related dementias.

31 May 2019

Study investigates if remote ischemic preconditioning could be beneficial to the brain

What if wearing a blood pressure cuff could help prevent stroke? In a new study, people who restricted their blood flow by wearing inflated blood pressure cuffs on an arm and leg showed signs of more controlled blood flow to their brain, a process that could be protective if blood flow is more severely restricted in the event of a stroke, according at a study published in the May 29, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology.

30 May 2019

Researchers find link between high LDL cholesterol levels and early-onset Alzheimer's

Researchers with the Atlanta Veterans Affairs Medical Center and Emory University have found a link between high LDL cholesterol levels and early-onset Alzheimer's disease.

29 May 2019

New fluorescent probe specifically labels microglia cells

Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels this type of macrophage. The cells were visualized in cell culture and in the live brains of rodents.

29 May 2019

Study uncovers new oncogenic function of receptor associated with Alzheimer's disease

Common and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease.

28 May 2019

Coat of proteins makes viruses more infectious and facilitates plaque formation in Alzheimer's

New research from Stockholm University and Karolinska Institutet shows that viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface.

27 May 2019

Newly discovered mechanism sheds light on how Parkinson’s disease can spread in the brain

Tiny channels between nerve cells are involved in a newly discovered mechanism of how Parkinson's disease can spread throughout the brain, according to new research from Linköping University, Sweden.

27 May 2019

New neurons continue to form in old age, even in people with Alzheimer's disease

In a new study from the University of Illinois at Chicago, researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age.

25 May 2019

Project promotes dialogue and participation in Alzheimer's research

Alzheimer's research affects many people and groups: patients and families, social organizations, professionals from many fields, companies and administrations.

25 May 2019

Study examines mortality risks among professional athletes

Professional football players appear to have a somewhat elevated risk of death, including higher risk of succumbing to cardiac and neurodegenerative diseases, compared with professional baseball players of similar age, according to new research.

24 May 2019

Rutgers-led study pinpoints key gene linked to impaired memory in Down syndrome

Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.

24 May 2019

Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

Higher education associated with later onset of Alzheimer's-related accelerated cognitive decline

Exercising the brain by learning and thinking is known to improve cognition. Now a new study by Stony Brook University researchers reveals that higher education is associated with later onset of Alzheimer's-related accelerated cognitive declines.

23 May 2019

People with bipolar disorder more likely to later develop Parkinson's disease

People who have bipolar disorder may be more likely to later develop Parkinson's disease than people who do not have bipolar disorder, according at a study published in the May 22, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 May 2019

New blood-based biomarker can detect Alzheimer's in its earliest stages

Alzheimer's disease is the major cause of dementia and so far, no effective treatment can prevent, delay or stop its progression.

22 May 2019

Inhibition of CRMP2 phosphorylation promotes axonal regeneration after optic nerve injury

A new study by Professor Toshio Ohshima of Waseda University has found that the inhibition of phosphorylation of collapsing response mediator protein 2, a microtubule-binding protein, suppresses degeneration of nerve fibers and promotes its regeneration after optic nerve injury.

22 May 2019

Alzheimer's Disease News and Research

Further Reading

Astrocytes protect neurons from damaging side effects of overactivity

Alzheimer's Drug Discovery Foundation announces first round of awards of Diagnostics Accelerator initiative

Study investigates if remote ischemic preconditioning could be beneficial to the brain

Researchers find link between high LDL cholesterol levels and early-onset Alzheimer's

New fluorescent probe specifically labels microglia cells

Study uncovers new oncogenic function of receptor associated with Alzheimer's disease

Coat of proteins makes viruses more infectious and facilitates plaque formation in Alzheimer's

Newly discovered mechanism sheds light on how Parkinson’s disease can spread in the brain

New neurons continue to form in old age, even in people with Alzheimer's disease

Project promotes dialogue and participation in Alzheimer's research

Study examines mortality risks among professional athletes

Rutgers-led study pinpoints key gene linked to impaired memory in Down syndrome

Spatial configuration of the genome is not inherited, but set up during embryogenesis

Higher education associated with later onset of Alzheimer's-related accelerated cognitive decline

People with bipolar disorder more likely to later develop Parkinson's disease

New blood-based biomarker can detect Alzheimer's in its earliest stages

Inhibition of CRMP2 phosphorylation promotes axonal regeneration after optic nerve injury

UNLV study reveals new mechanism in long-term memory retrieval

Researchers explore link between aging fat cells and Alzheimer's

Researchers identify enzymes that protect people from diabetic kidney disease

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