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New class of compounds can stop the reproduction of coronavirus

A human genetic mechanism hijacked by SARS-CoV-2, the coronavirus behind the COVID-19 pandemic, to help it spread also makes it vulnerable to a new class of drug candidates, a new study finds.

24 Jun 2021

New antibody conjugate delivers drugs to bone tumors and inhibits metastasis

Bone cancer is hard to treat and prone to metastasis. Research teams at Rice University and Baylor College of Medicine have a new strategy to attack it.

23 Jun 2021

Molecule derived from tarantula venom may help relieve chronic IBS pain

For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom.

23 Jun 2021

Insilico Medicine receives $255 million to develop AI and drug discovery capabilities

Insilico Medicine, a global leader in end-to-end artificial intelligence for target discovery, small molecule chemistry, and clinical development, announced that it has closed a $255 million from biotechnology experts to progress Insilico Medicine's current therapeutic programs into human clinical trials, initiate multiple new programs for novel and difficult targets, and further develop its AI and drug discovery capabilities.

23 Jun 2021

Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

In a cancer that has not seen new targeted therapies for over 20 years, MUSC Hollings Cancer Center researcher and oncologist Nancy Klauber-DeMore, M.D., is pioneering new discoveries.

22 Jun 2021

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

A new class of drugs that inhibits a "master switch" involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.

22 Jun 2021

Protein blueprint may aid in treatments for infertility and help protect future fertility

Researchers at the University of Cincinnati College of Medicine have developed a blueprint for a protein that plays an important role in the development and regulation of reproductive organs.

22 Jun 2021

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

The RDM Positive Impact Foundation is funding an ambitious $1.25 million research project at the UC Davis MIND Institute to study SYNGAP1.

22 Jun 2021

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor of physiology & biophysics and member of the Institute for Immunology at the University of California, Irvine.

22 Jun 2021

Study determines the mechanism behind respiratory inflammation and finds effective treatment

Applied Biological Laboratories (Applied Bio), a biopharmaceutical company focused on the respiratory disease market, announced that its study published online in Immunology, Inflammation and Disease was able to determine the mechanism behind respiratory inflammation and treat it effectively with Biovanta(TM), a 100% naturally derived, over-the-counter (OTC) drug for cold, cough and sore throat.

22 Jun 2021

Researchers develop new therapeutic approach for treating acute myeloid leukemia

Leukemia stem cells are rare cells that can renew themselves while continuing to generate malignant cells known as leukemic blasts. These cells are difficult to eradicate using chemotherapy drugs and frequently lead to recurrence of leukemia.

22 Jun 2021

Unrepaired DNA damage can increase the speed of aging, study suggests

Every day, our bodies face a bombardment of UV rays, ozone, cigarette smoke, industrial chemicals and other hazards.

21 Jun 2021

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

By the time people with Alzheimer's disease start exhibiting difficulty remembering and thinking, the disease has been developing in their brains for two decades or more, and their brain tissue already has sustained damage. As the disease progresses, the damage accumulates, and their symptoms worsen.

21 Jun 2021

Multivalent antibodies show high potency against SARS-CoV-2 in new study

A new study in the journal Nature Communications describes the process of converting a SARS-CoV-2 antibody into a multivalent form, thus enabling it to bind at various different points with its epitope.

21 Jun 2021

Can convalescent plasma therapy improve COVID-19 outcomes in patients with hematologic cancers?

A recent study discusses the findings of a study on patients with hematologic cancers who received convalescent plasma therapy following their diagnosis of COVID-19.

21 Jun 2021

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Recently, researchers discuss their development of cell membrane-based nanoparticles that successfully delivered dexamethasone directly to inflamed lung cells.

21 Jun 2021

New test is cheaper, easier, and can reliably diagnose SARS-CoV-2 infection

New lateral flow test Vigilant is cheaper, easier to use and as reliable as the current gold standard PCR test for diagnosing SARS-CoV-2 infection.

21 Jun 2021

Gasdermin D plays a key role in the maturation and release of IL-1α

Interluekin-1α (IL-1α) is an important part of the immune response, but until now it has been unclear how this molecule is processed from its precursor, pro-IL-1α, and exits the cell during inflammasome activation.

21 Jun 2021

Study paves the way for development of new therapeutics for C. difficile infection

A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.

18 Jun 2021

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

A new study, released as a preprint on bioRxiv* server, shows that a combination of the biological interferon-α and the small molecule nafamostat are effective against SARS-CoV-2 infection in vitro, as well as in vivo.

18 Jun 2021

Molecule News and Research

New class of compounds can stop the reproduction of coronavirus

New antibody conjugate delivers drugs to bone tumors and inhibits metastasis

Molecule derived from tarantula venom may help relieve chronic IBS pain

Insilico Medicine receives $255 million to develop AI and drug discovery capabilities

Combination of SFRP2 and PD-1 immunotherapy halts aggressive metastatic cancer in preclinical model

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

Protein blueprint may aid in treatments for infertility and help protect future fertility

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

Cancer immunotherapy may self-limit its efficacy in fighting tumors, study finds

Study determines the mechanism behind respiratory inflammation and finds effective treatment

Researchers develop new therapeutic approach for treating acute myeloid leukemia

Unrepaired DNA damage can increase the speed of aging, study suggests

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

Multivalent antibodies show high potency against SARS-CoV-2 in new study

Can convalescent plasma therapy improve COVID-19 outcomes in patients with hematologic cancers?

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

New test is cheaper, easier, and can reliably diagnose SARS-CoV-2 infection

Gasdermin D plays a key role in the maturation and release of IL-1α

Study paves the way for development of new therapeutics for C. difficile infection

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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