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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Scientists discover metabolite fueling aggressive brain tumor growth

Virtually all high-grade, aggressive gliomas in adults accumulate massive amounts of a metabolite called guanidinoacetate (GAA) that overstimulates nearby neurons and promotes tumor growth, according to new research from scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cell.

18 Sep 2026

New clues link Long COVID and POTS

Dizziness, fatigue, brain fog and a racing heart. They’re commonly associated with Long COVID, but new Adelaide University research suggests that for some people, these symptoms may also be indications of Postural orthostatic tachycardia syndrome (POTS), a debilitating and difficult-to-diagnose condition.

18 Sep 2026

Transplanted human cortical organoids filled most of a mouse cortex. Then they began to connect

Researchers created xenocortical mice by transplanting human cortical organoids into animals genetically depleted of much of their native cortex, allowing the human tissue to occupy most of the available cortical space and form anatomical connections throughout the host nervous system. The grafts developed diverse cortical cell types, including L5-ET and VEN-like neurons, generated organized neural activity, and produced measurable cellular and behavioral responses to hypoxic injury.

18 Sep 2026

Better fitness was linked to healthier brain structure, but not better memory

Researchers studying 353 cognitively unimpaired adults aged 60 to 94 found that higher muscular capacity was associated with lower basal ganglia perivascular space volume, while greater aerobic fitness was associated with greater gray matter volume and medial temporal lobe thickness. Fitness was not directly associated with global cognition or episodic memory, and evidence for cognitive reserve was limited, although VO₂max explained additional variation in delayed verbal memory beyond tau burden.

18 Sep 2026

Study identifies two opposing molecular patterns in autism models

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they converge on shared biological mechanisms?

17 Sep 2026

Sex-specific biological clocks reveal how aging differs across the body in women and men

Researchers developed 38 sex-specific biological aging clocks across 15 organ systems, finding differences between females and males in genetic architecture, molecular signatures, disease associations, and mortality patterns. Brain aging clocks were linked to progression from mild cognitive impairment to Alzheimer’s disease in both sexes and to sex-dependent cognitive trajectories among solanezumab-treated A4 participants, while the authors stressed that sex-pooled and sex-interaction models remain complementary approaches.

17 Sep 2026

Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see.

17 Sep 2026

Deafness prompts brain rewiring to enhance peripheral vision

The brains of people who are deaf from an early age re-wire to see more of what is happening in their visual periphery, new research has revealed.

17 Sep 2026

New indicators could accelerate development of anti-aging drugs

Twelve candidate indicators, based on studies in mice, could make developing anti-aging interventions faster-while offering new insights into age-related diseases.

17 Sep 2026

Time-restricted eating may slow early-stage Huntington's disease

A simple change in when people eat may offer a promising new approach for Huntington's disease, according to research led by Oregon Health & Science University.

17 Sep 2026

Existing anti-seizure drug slows the growth of diffuse midline gliomas

An existing anti-seizure drug slows the growth of a devastating group of childhood cancers, new Stanford Medicine-led research has shown.

17 Sep 2026

Groundbreaking technology uses quantum sensors to measure heart activity

Physicists at Johannes Gutenberg University Mainz (JGU) have developed a groundbreaking technology that uses quantum sensors to measure biomagnetic signals, such as heart activity.

17 Sep 2026

Post-concussion irritability linked to PTSD, chronic pain, and auditory difficulties

New research from the CU Anschutz Marcus Institute for Brain Health shows that irritability is strongly associated with post-traumatic stress disorder (PTSD) symptoms, chronic pain and difficulty understanding speech in noisy environments among military veterans with chronic mild traumatic brain injury (mTBI), or concussion.

17 Sep 2026

Some mice showed signs of stress resilience before the stress even began

Researchers found that mice later classified as resilient showed stronger coordination between neuronal OFF-periods and slow-wave activity in the prelimbic cortex even before social stress. After social defeat, resilient mice also showed a distinct reorganization of neuronal silence during NREM sleep, linking local sleep dynamics with behavioral resilience.

17 Sep 2026

New MRI measure maps blood flow and cellular organization

Researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have developed a new, noninvasive way to examine how blood flow and cellular organization align across the layers of the living human brain.

17 Sep 2026

High estrogen alters brain circuit causing temporary memory impairment during pregnancy

Many women usually say the same thing during pregnancy: they walk into a room and forget why, misplace their keys or struggle to follow a conversation.

17 Sep 2026

Genetic risk for PTSD varies across different types of trauma

A groundbreaking study reveals that your genes may make you more vulnerable to Post Traumatic Stress Disorder (PTSD) from certain types of trauma-particularly childhood neglect-than from others.

17 Sep 2026

Mindfulness and tai chi practices help cancer survivors manage symptoms

The cancer journey for many patients doesn’t end after treatment. Many live with long-term side effects that affect their ability to sleep and cause pain, impacting daily life.

16 Sep 2026

POTS identified in nearly two-thirds of Long COVID patients

Dizziness, fatigue, brain fog and a racing heart. They're commonly associated with Long COVID, but new Adelaide University research suggests that for some people, these symptoms may also be indications of Postural orthostatic tachycardia syndrome (POTS), a debilitating and difficult-to-diagnose condition.

16 Sep 2026

Military blast exposure associated with long-term health conditions

Exposure to high-level blasts from incoming explosive devices or land mines among military veterans is associated with an increased risk of several conditions such as seizures, neuropathy and stroke years later, according to a study published September 16, 2026, in Neurology, the medical journal of the American Academy of Neurology.

16 Sep 2026