Medicinal Chemistry News and Research

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Researchers lab-test molecule that may combat common cold virus

Researchers have lab-tested a molecule that can combat the common cold virus by preventing it from hijacking human cells.

15 May 2018

New compound could offer pain-relieving properties without risk of addiction

Researchers at the University of Michigan have engineered a new compound that animal tests suggest could offer the pain-relieving properties of opioids such as morphine and oxycodone without the risk of addiction.

24 Apr 2018

Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

Nosopharm, a company dedicated to the research and development of new anti-infective drugs, and the University of Illinois at Chicago today announce the publication of a study in Molecular Cell on the mechanism of action of odilorhabdins, a new class of antibiotics to combat antibiotic resistance.

9 Apr 2018

Research team identifies new class of antibiotics to fight drug resistance

Researchers from the University of Illinois at Chicago and Nosopharm, a biotechnology company based in Lyon, France, are part of an international team reporting on the discovery of a new class of antibiotics.

6 Apr 2018

Research uncovers ways to slow down progression of neurodegenerative conditions

A new paper in Bioorganic & Medicinal Chemistry Letters talks about the mechanism of influence of methanofullerenoles on hyperpolarized mitochondria.

30 Mar 2018

Scientists create synthesized antibiotic capable of treating superbugs

A "game changing" new antibiotic which is capable of killing superbugs has been successfully synthesized and used to treat an infection for the first time -- and could lead to the first new class of antibiotic drug in 30 years.

23 Mar 2018

UC Riverside researchers discover way to halt cancer metastasis

A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

23 Feb 2018

Chemist finds how to control blood sugar without usual side effects

Chemist Robert Doyle in the College of Arts and Sciences at Syracuse University has figured out how to control glucose levels in the bloodstream without the usual side effects of nausea, vomiting or malaise.

11 Feb 2018

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

A group of Brazilian scientists achieved promising results using isolated compounds from the venom of the South American rattlesnake in combat of hepatitis C.

8 Feb 2018

UIC scientists identify new chemical compound to stop bacteria from causing sickness

A study published in the Journal of Biological Chemistry is the first to describe a signaling pathway that affects communication -- a process called quorum sensing -- between Streptococcus bacteria cells.

6 Feb 2018

Revolutionary technology could radically change cryopreservation of cells and tissues

Everyone knows that freezing things is an imperfect process. Take frozen food, for example - most have experienced those frozen ice crystals that change the texture and taste of their favorite meal.

6 Feb 2018

Asynt’s DrySyn MAXI heating system used for reproducible scale-up of medicinal chemistry reactions

Asynt reports that medicinal chemistry specialists Charnwood Molecular (Loughborough UK) have been using the DrySyn MAXI heating system to successfully and reproducibly scale up syntheses within their contract research laboratories.

6 Feb 2018

SUTD-NCL team completes phenotypic screening of MMV Malaria Box against pathogenic parasites

A Singapore-India collaborative research project between the Singapore University of Technology & Design and CSIR-National Chemical Laboratories completed phenotypic screening of a large collection of potent chemical inhibitors (known as MMV Malaria Box), against pathogenic parasites Toxoplasma gondii and Plasmodium falciparum, causative agents of human toxoplasmosis and malaria.

27 Jan 2018

Artificial sweetener could lead to development of cancer therapies with less side effects

Artificial sweeteners are used in diet drinks and foods but also could someday be used as treatments targeting carbonic anhydrase IX (CA IX), a protein associated with aggressive cancers.

24 Jan 2018

Potential male birth control pill could be developed from arrow poison

Women have many options for oral contraceptives that are safe, effective and reversible, but despite decades of research, men have none.

18 Jan 2018

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

The University of Kansas' Center for Molecular Analysis of Disease Pathways, a National Institutes of Health Center of Biomedical Research Excellence, recently earned a second phase of grant funding in the amount of $10.8 million for an additional five years.

19 Dec 2017

Researchers receive DoD grant to identify alternatives to opioids for pain management

What does a marine snail's ability to kill prey with two shots of venom have to do with the opioid epidemic ravaging the United States?

29 Nov 2017

Scientists develop potential new antidepressant with unique mechanism of action

A potential new antidepressant and antianxiety treatment with a unique mechanism of action has been developed by scientists at the University of Bath.

6 Nov 2017

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Intriguing antitumor activity is found in a very promising class of natural compounds: cyclic depsipeptides, which have a challenging structure that makes their investigation difficult. Now, Chinese scientists have established the synthesis of a member compound, which is especially promising in killing pancreatic cancer stem cells.

28 Oct 2017

Clarivate Analytics includes eBooks for coverage in Book Citation Index

Clarivate Analytics has recently included the following 16 eBooks for coverage in Book Citation Index. The Book Citation Index in Web of Science™ Core Collection connects a library's book collection to powerful new discovery tools, giving researchers the ability to quickly and easily identify and access the most relevant books.

30 Sep 2017

Medicinal Chemistry News and Research

Researchers lab-test molecule that may combat common cold virus

New compound could offer pain-relieving properties without risk of addiction

Nosopharm and UIC reveal pharmacology of new class of antibiotics to combat drug resistance

Research team identifies new class of antibiotics to fight drug resistance

Research uncovers ways to slow down progression of neurodegenerative conditions

Scientists create synthesized antibiotic capable of treating superbugs

UC Riverside researchers discover way to halt cancer metastasis

Chemist finds how to control blood sugar without usual side effects

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

UIC scientists identify new chemical compound to stop bacteria from causing sickness

Revolutionary technology could radically change cryopreservation of cells and tissues

Asynt’s DrySyn MAXI heating system used for reproducible scale-up of medicinal chemistry reactions

SUTD-NCL team completes phenotypic screening of MMV Malaria Box against pathogenic parasites

Artificial sweetener could lead to development of cancer therapies with less side effects

Potential male birth control pill could be developed from arrow poison

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

Researchers receive DoD grant to identify alternatives to opioids for pain management

Scientists develop potential new antidepressant with unique mechanism of action

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Clarivate Analytics includes eBooks for coverage in Book Citation Index

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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