Platelets News and Research

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ACE2 and pattern recognition receptor genes increase with age

A recent study by researchers in California and published on the preprint server bioRxiv* in June 2020 shows that advancing age is associated with increased expression of pattern recognition receptor (PRR) genes and ACE2 receptors, possibly accounting in part for the increased severity of the disease in older adults.

17 Jun 2020

Researchers design new microfluidic device to help detect blood clots

Researchers in the Department of Biomedical Engineering at Texas A&M University are working on an entirely new way to detect blood clots, especially in pediatric patients.

3 Jun 2020

UC physician-researcher explores why TAVR doesn't work well for some patients

A University of Cincinnati physician-researcher says unlocking the key to how platelets function before, after and during transcatheter aortic valve replacement (TAVR) may provide insight as to why some patients undergoing the heart procedure have better outcomes than others.

3 Jun 2020

Blood clotting disorders may explain some of the worst symptoms of COVID-19

The hypothesis that blood clotting disorders may explain some of the worst symptoms of COVID-19, including respiratory failure and pulmonary fibrosis, was suggested in mid-April by researchers in Brazil affiliated with the University of São Paulo's Medical School (FM-USP) via an article accepted for publication by the Journal of Thrombosis.

27 May 2020

A new method to monitor blood damage in real-time

According to the National Kidney Foundation, more than 37 million people are living with kidney disease.

21 May 2020

Study highlights need to focus on medications that address clot formation

Earlier this week, the BBC reported that one-third of COVID-19 patients developed dangerous blood clots.

19 May 2020

Platelets can intensify inflammatory processes, study shows

Platelets not only play a key role in blood clotting, but can also significantly intensify inflammatory processes.

12 May 2020

New tool could help physicians diagnose the cause of blood clots

A new tool using cutting-edge technology is able to distinguish different types of blood clots based on what caused them, according to a study published in eLife.

12 May 2020

More selective elimination of leukemic and hematopoietic stem cells

Acute myeloid leukemia is an aggressive cancer of the blood-forming system. It affects the hematopoietic stem cells, or blood stem cells, of various white blood cells and of the red blood cells and platelets.

8 May 2020

Innovative device could help treat babies with blood disorders

With severe blood disorders, such as leukemia, doctors often rely on leukapheresis, a procedure in which large machines extract whole blood from patients to separate white blood cells from the rest of the blood, which is then returned back to the patient.

8 May 2020

New preclinical study shows promise for treating necrotizing enterocolitis

Necrotizing enterocolitis (NEC), a rare inflammatory bowel disease, primarily affects premature infants and is a leading cause of death in the smallest and sickest of these patients.

6 May 2020

New initiative to speed up development and commercialization of COVID-19 testing technologies

UMass Medical School and UMass Lowell will perform a key role in a new National Institutes of Health initiative aimed at speeding innovation, development and commercialization of COVID-19 testing technologies via their Center for Advancing Point of Care Technologies collaboration.

4 May 2020

New study could improve our understanding about platelets

University of Kentucky College of Medicine researcher Sidney Whiteheart has been awarded a prestigious Outstanding Investigator Award from the National Heart, Blood and Lung Institute for his research on how platelets function in hemostasis and during immune responses.

29 Apr 2020

Her genetic test revealed a microscopic problem — and a jumbo price tag

Michelle Kuppersmith, 32, feels great, works full time and exercises three to four times a week. So she was surprised when a routine blood test found that her body was making too many platelets, which help control bleeding.

31 Mar 2020

Ticagrelor therapy, without aspirin, can benefit patients with acute coronary syndrome

Patients with acute coronary syndrome (ACS) who stopped taking aspirin three months after the insertion of a coronary stent and then took the anti-platelet medication ticagrelor alone for nine months had fewer episodes of bleeding and no increase in heart attacks, stroke or other adverse events caused by blockages in the arteries, compared with patients who took both aspirin and ticagrelor for a year.

31 Mar 2020

Taking ticagrelor alone better for patients with complex heart disease

Patients with complex heart disease who stopped taking aspirin three months after the insertion of one or more coronary stents and then took the anti-platelet medication ticagrelor alone for a year had fewer episodes of bleeding and no increase in heart attacks, stroke or other adverse events caused by blockages in the arteries, compared with patients who took both aspirin and ticagrelor over the same period.

30 Mar 2020

Treatment with ticagrelor alone reduces adverse events in patients with diabetes

Patients with diabetes who stopped taking aspirin three months after the insertion of a coronary stent and then took the anti-platelet medication ticagrelor alone for a year had fewer episodes of bleeding and no increase in heart attacks, stroke or other adverse events caused by blockages in the arteries, compared with patients who took both aspirin and ticagrelor for a year.

30 Mar 2020

Adding antiplatelet therapy to oral anticoagulants raises risk for TAVR patients with atrial fibrillation

Patients with atrial fibrillation who took oral anticoagulants alone after undergoing transcatheter aortic valve replacement had a lower rate of bleeding complications without an increased risk of clotting-related complications compared to patients who took antiplatelet medication in addition to oral anticoagulants, in a trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology.

29 Mar 2020

New 'more effective' stem cell transplant method could improve treatment of blood diseases

Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults.

26 Mar 2020